Leica Science Lab - Tag : Glioma https://www.leica-microsystems.com//science-lab/tag/tags/glioma/show/Tag/ Article tagged with Glioma en-US https://www.leica-microsystems.com/16544 Optical Coherence Tomography Handheld Optical Coherence Tomography During Sedation in Young Children With Optic Pathway Gliomas Monitoring young children with optic pathway gliomas (OPGs) for visual deterioration can be difficult owing to age-related noncompliance. Optical coherence tomography (OCT) measures of retinal nerve fiber layer (RNFL) thickness have been proposed as a surrogate marker of vision but this technique is also limited by patient cooperation. To determine whether measures of circumpapillary RNFL thickness, acquired with handheld OCT (HH-OCT) during sedation, can differentiate between young children with and without vision loss from OPGs. https://www.leica-microsystems.com//science-lab/handheld-optical-coherence-tomography-during-sedation-in-young-children-with-optic-pathway-gliomas/ Mon, 09 Nov 2015 13:13:00 +0000 https://www.leica-microsystems.com/14774 Laser Microdissection Neuroscience Identification of Molecular Pathways Facilitating Glioma Cell Invasion In Situ Gliomas are mostly incurable secondary to their diffuse infiltrative nature. Thus, specific therapeutic targeting of invasive glioma cells is an attractive concept. As cells exit the tumor mass and infiltrate brain parenchyma, they closely interact with a changing micro-environmental landscape that sustains tumor cell invasion. https://www.leica-microsystems.com//science-lab/identification-of-molecular-pathways-facilitating-glioma-cell-invasion-in-situ/ Mon, 22 Dec 2014 09:35:00 +0000 https://www.leica-microsystems.com/10286 Live-Cell Imaging Multiphoton Microscopy Direct In Vivo Evidence for Tumor Propagation by Glioblastoma Cancer Stem Cells Cancer research using multiphoton microscopy. High-grade gliomas (World Health Organization grade III anaplastic astrocytoma and grade IV glioblastoma multiforme), the most prevalent primary malignant brain tumors, display a cellular hierarchy with self-renewing, tumorigenic cancer stem cells (CSCs) at the apex. While the CSC hypothesis has been an attractive model to describe many aspects of tumor behavior, it remains controversial due to unresolved issues including the use of ex vivo analyses with differential growth conditions. https://www.leica-microsystems.com//science-lab/direct-in-vivo-evidence-for-tumor-propagation-by-glioblastoma-cancer-stem-cells/ Fri, 12 Jul 2013 13:21:00 +0000