Implementing Ergonomic Design for Microscope Workstations
This study evaluated the effect of an occupational therapy ergonomics intervention on the workstation design and body positioning of microscope workers at a fiber optics facility.Read article
Beware of "Empty" Magnification
This article explains how to avoid the phenomen of "empty magnification" in microscopy.Read article
Digital Cameras
Manufacturers digital cameras race to outdo each other with ever-increasing numbers of megapixels. The world record for professional medium format digital cameras has now surpassed 60 megapixels per…Read article
How Sharp Images Are Formed
In microscopy, depth of field is often seen as an empirical parameter. In practice it is determined by the correlation between numerical aperture, resolution and magnification. For the best possible…Read article
Fluorescence in Microscopy
Fluorescence microscopy is a special form of light microscopy. It uses the ability of fluorochromes to emit light after being excited with light of a certain wavelength. Proteins of interest can be…Read article
Polarization Contrast
Polarization microscopy is routinely applied in material sciences and geology to identify minerals on the basis of characteristic refraction properties and colors. In biology, polarization microscopy…Read article
Photo Effects of Light
Molecules and atoms can exist in different quantum states. These states are dedicated to different energy levels; the quantum state with the lowest energy is called the ground state. Every state of…Read article
An Introduction to Fluorescence
Fluorescence is widely used in microscopy and an important tool for observing the distribution of specific molecules. Most molecules in cells do not fluoresce. They therefore have to be marked with…Read article
Integrated Modulation Contrast (IMC)
Hoffman modulation contrast has established itself as a standard for the observation of unstained, low-contrast biological specimens. The integration of the modulator in the beam path of themodern…Read article
Differential Interference Contrast (DIC)
Differential interference contrast (DIC) microscopy is a good alternative to brightfield microscopy for gaining proper images of unstained specimens that often only provide a weak image in…Read article
Phase Contrast
Phase contrast is an optical contrast technique for making unstained phase objects (e.g. flat cells) visible under the light microscope. Cells that appear inconspicuous and transparent in brightfield…Read article
Optical Contrast Methods
Optical contrast methods give the potential to easily examine living and colorless specimens. Different microscopic techniques aim to change phase shifts caused by the interaction of light with the…Read article
Basic Principles of Luminescence
There are a lot of light-emitting processes occurring in nature. Luminescence is an umbrella term for those kinds of events where light emission is not the result of high temperatures. This article…Read article
Scientific Illustration and Animation for Research Scientists
One of the crucial tasks of a research scientist is reporting and communicating about his work. This is vital for cutting edge research; it is crucial to gain insights from other experts, to get a…Read article
Optical Microscopes – Some Basics
The optical microscope has been a standard tool in life science as well as material science for more than one and a half centuries now. To use this tool economically and effectively, it helps a lot to…Read article
How to Clean Microscope Optics
Clean microscope optics are essential for obtaining good microscope images. If they are dirty, the microscope should be cleaned to avoid a loss of quality. If you decide to do this yourself, you…Read article
Video Tutorial: How to Change the Bulb of a Fluorescence Lamp Housing
When applying fluorescence microscopy in biological applications, a lamp housing with mercury burner is the most common light source. This video tutorial shows how to change the bulb of a traditional…Read article
Video Tutorial: How to Align the Bulb of a Fluorescence Lamp Housing
The traditional light source for fluorescence excitation is a fluorescence lamp housing with mercury burner. A prerequisite for achieving bright and homogeneous excitation is the correct centering and…Read article
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