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Learn & Share: White Confocal

Confocal microscopy has brought a major turning point for the imaging techniques in biology and medicine. In contrast to material applications, biomedical research uses, in most cases, fluorescent stains to visualize specific structures and components of biological samples. Typically, three to five different fluorochromes are used for simultaneous detection. The fluorochromes vary significantly, to match the specific requirements for the given experiment. Consequently, the excitation and emission colors also vary and call for a maximum of spectral flexibility. A series of ingenious inventions has finally lead to a fully tunable confocal microscope. The design concept leaves no spectral limitations, and is hence called the “White Confocal”. It combines a white light laser source, tunable excitation filtering, tunable beam-splitting and tunable emission-detection – with full access to the keys for all colors.

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Communities and Web Sources network for scientists Microscopy Mailing List, University of Minnesota tools, video lectures on biology and microscopy

bitesizebio.comOnline magazine and community for molecular and cell biology researchers

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www.cellimagelibrary.orgPublic resource database of images, videos, and animations of cells meta search engine for genes and proteins

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Journals of open access journals EMBO Journal

www.lifescied.orgCBE-Life Sciences Education – an ASCB online journal publication of exceptional research articles of Cell Science Journal of Experimental Biology Disease Models & Mechanisms Journal of Life Science Methods of Journals and Proceedings in Optics and Photonics - peer-reviewed journals on applied research in optics and photonics of Biophotonics, peer-reviewed, open-access, online publication B - the Royal Society's biological research journal Journal for microscopists

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