The term photomanipulation encompasses a range of techniques that utilize the properties of fluorescent molecules to initiate events and observe how dynamic complexes behave over time in living cells.
Whether bleaching, activating, converting, ablating or combining techniques, researchers need to have a system fully capable of performing and capturing events in high resolution.
Leica Photomanipulation Products
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Scientific CMOS camera - For Life Science Imaging Applications and Analysis
sCMOS Microscope Camera
THUNDER Imagers provide you with a solution for advanced 3D cell culture assays, whether you want to study stem cells, spheroids, or organoids.
Fluorescence Recovery After Photobleaching (FRAP) experiments require fast yet gentle and accurate bleaching of specific regions of interest (ROIs).
FRAP experiments typically are used in biological studies of cellular kinetics, such as membrane diffusion and protein binding.
Leica offers two solutions for FRAP experiments with the DMi8 inverted microscope
Utilize the latest advances in photoswitchable fluorescent proteins.
By selectively activating regions of your cells, you can precisely follow how specific molecules behave in cells over time.
The Infinity Scanner gives you full flexibility to choose the wavelength, size, and shape of your activation regions.
Full integration into LAS X microscope software
With full integration into LAS X software, you can design and perform photoactivation experiments with the ease of a fully integrated system.