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Science Lab
Science Lab
The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!
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![Stereo microscopes are often considered the workhorses of laboratories and production sites. Stereo microscopes are often considered the workhorses of laboratories and production sites.](/fileadmin/_processed_/f/2/csm_Ivesta_3_series_6f1b8e9b73.jpg)
Key Factors to Consider When Selecting a Stereo Microscope
This article explains key factors that help users determine which stereo microscope solution can best meet their needs, depending on the application.
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![Strain from using a microscope can lead to musculoskeletal pain. Strain from using a microscope can lead to musculoskeletal pain.](/fileadmin/_processed_/b/1/csm_AdobeStock_musculoskeletal_pain_893e89f2c0.jpg)
Microscope Ergonomics
This article explains microscope ergonomics and how it helps users work in comfort, enabling consistency and efficiency. Learn how to set up the workplace to keep good posture when using a microscope.
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![Inspection microscope image of a printed circuit board (PCB) taken with a ring light (RL) and near vertical illumination (NVI). Inspection microscope image of a printed circuit board (PCB) taken with a ring light (RL) and near vertical illumination (NVI).](/fileadmin/_processed_/2/7/csm_PCB_taken_with_a_ring_light_and_near_vertical_illumination_744697ca43.jpg)
Microscope Illumination for Industrial Applications
Inspection microscope users can obtain information from this article which helps them choose the optimal microscope illumination or lighting system for inspection of parts or components.
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![Electronic component Electronic component](/fileadmin/_processed_/a/1/csm_Electronic_component_1081697df6.jpg)
Top Challenges for Visual Inspection
This article discusses the challenges encountered when performing visual inspection and rework using a microscope. Using the right type of microscope and optical setup is paramount in order to…
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![Visual inspection of a PCBA with the Ivesta 3 Greenough stereo microscope. Visual inspection of a PCBA with the Ivesta 3 Greenough stereo microscope.](/fileadmin/_processed_/a/a/csm_Ivesta_3_integrated_monitor_users_2_fc7f6bf183.jpg)
How to Select the Right Solution for Visual Inspection
This article helps users with the decision-making process when selecting a microscope as a solution for routine visual inspection. Important factors that should be considered are described.
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![Comparison when observing a rodent model organism with a Greenough versus CMO (common main objective) stereo microscope for a task like surgery. Comparison when observing a rodent model organism with a Greenough versus CMO (common main objective) stereo microscope for a task like surgery.](/fileadmin/_processed_/b/9/csm_Observing_rodent_model_organism_Greenough_vs_CMO_stereo_microscope_f818eec9a5.jpg)
Rodent and Small-Animal Surgery
Learn how you can perform rodent (mouse, rat, hamster) and small-animal surgery efficiently with a microscope for developmental biology and medical research applications by reading this article.
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![Gene editing with Cas9 Gene editing with Cas9](/fileadmin/_processed_/4/2/csm_Gene_editing_with_Cas9_teaser_01_c307b7d38c.jpg)
Gene Editing with CRISPR/Cas9 - Breakthrough in Genome Engineering
The CRISPR/Cas9 system is one of several different bacterial systems for defense against viral attacks. It consists of two main components. One is a small piece of RNA which binds to the viral target…
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![Transgenic zebrafish larva where fluorescent proteins label the heart muscle blue, blood and blood vessels red, and all circulatory system cells green. Image recorded with a M205 FA microscope. Transgenic zebrafish larva where fluorescent proteins label the heart muscle blue, blood and blood vessels red, and all circulatory system cells green. Image recorded with a M205 FA microscope.](/fileadmin/_processed_/e/6/csm_Zebrafish_Stereo-Report_02_9a4b0c50e5.jpg)
Imaging and Analyzing Zebrafish, Medaka, and Xenopus
Discover how to image and analyze zebrafish, medaka, and Xenopus frog model organisms efficiently with a microscope for developmental biology applications from this article.
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![Fluorescence stereo microscope image of anesthetized Mediterranean fruit flies recorded with a M205 stereo microscope. Fluorescence stereo microscope image of anesthetized Mediterranean fruit flies recorded with a M205 stereo microscope.](/fileadmin/_processed_/4/9/csm_Mediterranean_fruit_flies_recorded_with_a_Leica_M205_FA_02_dfa6422e24.jpg)
Investigating Fruit Flies (Drosophila melanogaster)
Learn how to image and investigate Drosophila fruit fly model organisms efficiently with a microscope for developmental biology applications from this article.