
High Pressure Freezer Leica EM ICE
High pressure freezing with the possibility of light and electrical stimulation
High pressure freezing is key for the study of intricate changes in fine structure or cellular dynamics.
- Cryo-immobilize your aqueous samples under high pressure with a unique freezing principle and uncover secrets of the cellular process.
- Capture and resolve highly dynamic processes at the nanometer scale with millisecond precision.
The EM ICE solution, combining superior high pressure freezing with the possibility of light and electrical stimulation, is the platform for your discoveries.
Superior cryo-fixation quality
Currently cryo-fixation is the only way to fix cellular constituents without introducing significant structural alterations.
The EM ICE solution uses a unique, alcohol-free freezing principle to allow a superior cryo-fixation of the specimen enabling better quality results to be obtained:
- No alcohol in the chamber leads to a faster pressure increase and immediate cooling of the specimen
- No alcohol residue on the carrier or the specimen
- Precisely define the timing for light and electrical stimulation

Micrographs courtesy of Drs Syed (NIH/NIDCR) and Bleck (NIH/NHLBI).