Loading...
![[Translate to chinese:] Multicolor fixed STED image. Inner ear section, mouse, TauSTED Xtend 589 on AF488 and TauSTED Xtend 775 on AF633-Phalloidin. Sample courtesy of Dennis Derstrof, Klinik für Hals-, Nasen und Ohrenheilkunde, Universität Marburg & Prof. Dr. Dominik Oliver aus dem Institut für Physiologie und Pathophysiologie, Abteilung für Neurophysiologie, Universität Marburg.](/fileadmin/_processed_/c/a/csm_Inner_ear_section_mouse_multicolor_fixed_TauSTED_Xtend_1a1a0b424b.jpg "[Translate to chinese:] Multicolor fixed STED image. Inner ear section, mouse, TauSTED Xtend 589 on AF488 and TauSTED Xtend 775 on AF633-Phalloidin.")
细胞活成像的纳米级扩展
新的STED显微技术方法——TauSTED Xtend，使得在纳米级别下对活体完整样本进行扩展多色成像成为可能。通过结合空间和寿命信息，TauSTED Xtend提供了额外一层信息，允许在极低的光剂量下分辨小细节并在整体结构中解析它们。
![[Translate to chinese:] Five-color FLIM-STED](/fileadmin/_processed_/a/3/csm_5-color_FLIM-STED_9d88340e60.jpg "[Translate to chinese:] Five-color FLIM-STED")
Loading...
A Versatile Palette of Fluorescent Probes
Researchers at the Max Planck Institute for Medical Research in Heidelberg have developed a general strategy to synthesize live-cell compatible fluorogenic probes, and the result are the new MaP (Max…
Loading...
Benefits of Combining STED and Lifetime
In this interview, Professor Alberto Diaspro talks about the advantages of the White Light Laser and the TauSTED capabilities of STELLARIS 8 STED. He speaks about his experience with the confocal…
Loading...
癌细胞中的DNA复制
DNA复制机制和共转录R环之间发生冲突时，会导致癌细胞基因组不稳定性，进而影响DNA合成。本文中，我们展示了ATP依赖性染色质重构INO80复合体可以促进R环解析，防止癌细胞中的复制相关的DNA损伤。
我们使用STED超高分辨率显微镜进行测量，INO80和R环之间具有前所未有的精密共定位。
Loading...
Kinetochore Assembly during Mitosis with TauSTED on 3D
Three-dimensional organization of the mitotic spindle together with the distribution of CENP-C and BUB1 based on TauSTED with multiple STED lines (592, 660 and 775 nm) can provide insights on…
Loading...
Regulators of Actin Cytoskeletal Regulation and Cell Migration in Human NK Cells
Dr. Mace will describe new advances in our understanding of the regulation of human NK cell actin cytoskeletal remodeling in cell migration and immune synapse formation derived from confocal and…
Loading...
使用 LIGHTNING 可从样本中获得丰富的信息
LIGHTNING 是一个自适应的信息提取过程，可以完全自动化地呈现原本不可见的微小结构和细节。 与为整个图像使用全局参数集的传统技术不同，LIGHTNING 为每一个像素计算一个适当的参数集，尽力还原细节。