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Kinetochore Assembly during Mitosis with TauSTED on 3D

TauSTED: pushing STED beyond its limits with lifetime


Three-dimensional organization of the mitotic spindle together with the distribution of CENP-C and BUB1 based on TauSTED with multiple STED lines (592, 660 and 775 nm) can provide insights on kinetochore assembly. 

TauSTED Video

*Details of how this sample is used to understand kinetochore assembly can be read in Sacristan, C. et al. Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis. Nat. Cell Biol. 20, 800–810(2018).

Further reading

Application note in Pushing STED beyond its limits with TauSTED

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