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Confocal Microscopes

Confocal microscopes from Leica Microsystems are partners in top level biomedical research and surface analysis in material science applications, offering unprecedented precision in three-dimensional imaging and exact examination of subcellular structures and dynamic processes.

Modular concept of our confocal microscopes

High-speed imaging supplies the data for a wide range of integrated analytical techniques. Our confocal microscopes are based on a modular concept that enables flexible upgrading and integration of innovative technology all the way to the nano range with STED 3X.

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Contact a local imaging specialist for expert advice on the right Confocal Microscopy system for your needs.

Confocal Microscopes 14

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Confocal Laser Scanning Microscope SP8 LIGHTNING

SP8 LIGHTNING

Super-resolution live cell imaging in multicolor

Histological section from cat eye. Simultaneous spectral (grey) and FLIM (color) confocal imaging reveals contrast by lifetime. Acquisition and visualization using SP8 FALCON and LAS X software.

SP8 FALCON

The contrast is clear. Lifetime imaging in an instant

SP8 DIVE

The first multiphoton microscope with spectrally tunable detection.

Maximum information from each specimen with LIGHTNING

LIGHTNING

The maximum of information from each specimen

Leica TCS SP8 CARS Confocal Microscope-Label Free Imaging

Leica TCS SP8 CARS

Label-free imaging of native specimens

Leica TCS SP8 DLS

Leica TCS SP8 DLS

Combining Light Sheet and Confocal

Leica TCS SP8 X Spectral Characterization

Leica TCS SP8 X

Optimal excitation of any dye with white light laser covering the full visible spectrum

Leica TCS SPE with Leica DMi8 and climate chamber

Leica TCS SPE

The personal spectral confocal for daily research

Leica HyD for photon counting

Leica HyD

The hybrid detector for super-sensitive imaging and photon counting

High Content Screening Automation-Leica HCS A

Leica HCS A

High content screening automation

Leica motCORR Microscope Objective

Leica motCORR Objectives

Fast adjustment to varying RI for best optical performance in 3D

3D Optical Surface Metrology System

Leica DCM8

Digital microscope for 3D surface measurement in production and research

Smart monitoring and service for scientific instruments RemoteCare

RemoteCare

Smart monitoring and service option for your microscope

Featured image

Mouse embryo mosaic image

High resolution mouse embryo mosaic image of 722 tiles containing 190 Megapixels. FLIM data fitted with four characteristic fluorescence lifetimes, color coded. Acquisition: 1:23 h. Analysis: 1:00 h

SP8 FALCON

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Confocal Microscopes Latest News

New Light Shed on the Nanodomain Organization of the Endoplasmic Reticulum (ER)

The endoplasmic reticulum (ER) is a continuous membrane organelle in charge of protein synthesis, lipid synthesis and detoxification. The ER structure…

Leica Science Lab

Image Gallery: THUNDER Imager

To help you answer important scientific questions, THUNDER Imagers eliminate the out-of-focus blur that clouds the view of thick samples when using…

Leica Science Lab

Stimulated Raman Scattering Microscopy Probes Neurodegenerative Disease

Despite decades of research, the molecular mechanisms underlying some of the most severe neurodegenerative diseases, such as Alzheimer’s or…

Leica Science Lab

Imaging Intracellular Temperature using Fluorescence Lifetime Imaging Microscopy (FLIM)

This video shows the presentation of Dr. Kohki Okabe given at the 9th Congress of the Federation of Asian and Oceanian Physiological Society (FAOPS)…

Leica Science Lab

Chat with Dr. Thomas Mathivet about In Vivo Cardiovascular Imaging of the Brain

Dr. Thomas Mathivet, working at the Cardiovascular Institute in Paris, France, was interviewed by Dr. Luis Alvarez, Product Application Manager,…

Leica Science Lab

Pore Scale Visualization of Drainage in 3D Porous Media by Confocal Microscopy

This work reports new interesting findings concerning porous media infiltration which have direct implications for the fields of energy (oil recovery)…

Leica Science Lab

SP8 FALCON: a novel concept in fluorescence lifetime imaging enabling video-rate confocal FLIM

SP8 FALCON (FAst Lifetime CONtrast) is a fast and completely integrated fluorescence lifetime imaging microscopy (FLIM) confocal platform. SP8 FALCON…

Leica Science Lab

Coherent Raman Scattering Microscopy Publication List

CRS (Coherent Raman Scattering) microscopy is an umbrella term for label-free methods that image biological structures by exploiting the…

Leica Science Lab

Development of fluorescence lifetime imaging microscopy (FLIM) and its relevance for functional imaging

Prof. Ammasi Periasamy, Director, Keck Center for Cellular Imaging, University of Virginia, was interviewed by Dr. Giulia Ossato, Product Manager…

Leica Science Lab
Human Kidney Organoid, hESC-derived Podocytes

Multiphoton imaging bolsters findings on in vitro differentiation of pluripotent stem cell-derived podocyte

The renal corpuscle of the kidney comprises a glomerular vasculature embraced by podocytes and supported by mesangial myofibroblasts. Their combined…

Leica Science Lab