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Confocal Microscopes

Confocal microscopes from Leica Microsystems are partners in top level biomedical research and surface analysis in material science applications, offering unprecedented precision in three-dimensional imaging and exact examination of subcellular structures and dynamic processes.

Modular concept of our confocal microscopes

High-speed imaging supplies the data for a wide range of integrated analytical techniques. Our confocal microscopes are based on a modular concept that enables flexible upgrading and integration of innovative technology all the way to the nano range with STED 3X.

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Contact a local imaging specialist for expert advice on the right Confocal Microscopy system for your needs.

Confocal Microscopes 14

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Confocal Laser Scanning Microscope SP8 LIGHTNING

SP8 LIGHTNING

Super-resolution live cell imaging in multicolor

Histological section from cat eye. Simultaneous spectral (grey) and FLIM (color) confocal imaging reveals contrast by lifetime. Acquisition and visualization using SP8 FALCON and LAS X software.

SP8 FALCON

The contrast is clear. Lifetime imaging in an instant

Maximum information from each specimen with LIGHTNING

LIGHTNING

The maximum of information from each specimen

SP8 DIVE

Deep In Vivo Explorer multiphoton imaging solution with tunable spectral detector

Leica TCS SP8 CARS Confocal Microscope-Label Free Imaging

Leica TCS SP8 CARS

Label-free imaging of native specimens

Leica TCS SP8 DLS

Leica TCS SP8 DLS

Combining Light Sheet and Confocal

Leica TCS SP8 X Spectral Characterization

Leica TCS SP8 X

Optimal excitation of any dye with white light laser covering the full visible spectrum

Leica TCS SPE with Leica DMi8 and climate chamber

Leica TCS SPE

The personal spectral confocal for daily research

Leica HyD for photon counting

Leica HyD

The hybrid detector for super-sensitive imaging and photon counting

High Content Screening Automation-Leica HCS A

Leica HCS A

High content screening automation

Leica motCORR Microscope Objective

Leica motCORR Objectives

Fast adjustment to varying RI for best optical performance in 3D

3D Optical Surface Metrology System

Leica DCM8

Digital microscope for 3D surface measurement in production and research

Smart monitoring and service for scientific instruments RemoteCare

RemoteCare

Smart monitoring and service option for your microscope

Featured image

Mouse embryo mosaic image

High resolution mouse embryo mosaic image of 722 tiles containing 190 Megapixels. FLIM data fitted with four characteristic fluorescence lifetimes, color coded. Acquisition: 1:23 h. Analysis: 1:00 h

SP8 FALCON

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Confocal Microscopes Latest News

Where to go? Cellular Migration requires coordinated Transitions of Actin Cortex

Plants, Bacteria, and Fungi possess a rigid cell wall that protects the cell and gives it shape. Animal cells, such as mammalian cells, have no outer…

Leica Science Lab

Cellular Motility: Microtubules, Motor Proteins and Tau-Proteins

Cellular motility is based on motor-proteins that can bind to filamentous scaffold proteins and – under consumption of ATP – can “crawl” on these…

Leica Science Lab

How FRET/FLIM Biosensors and Lifetime Imaging Helped Identify the Importance of Zinc for Human B-Cell Development

In her latest studies, Dr. Mukta Deobagkar-Lele investigated the role of ZIP7, a zinc transporter protein, in modulating B cell activity and its…

Leica Science Lab
Cavanillesia Arborea 10mm Core

Improved tree-ring visualization using autofluorescence

Autofluorescence can be a very practical tool for the visualization of growth rings in wood, especially when these structures are hard to distinguish,…

Leica Science Lab
Cover glomerulus

The Guide to STED Sample Preparation

This guide is intended to help users optimize sample preparation for stimulated emission depletion (STED) nanoscopy, specifically when using the TCS…

Leica Science Lab

Single-residue bioorthogonal labeling of G protein-coupled receptors (GPCRs) in live cells for quantitative analysis

To perform quantitative studies of membrane bound G protein-coupled receptors (GPCRs) with high-performance microscopy, the proteins must first be…

Leica Science Lab

Coherent Raman Scattering Microscopy Publication List

CRS (Coherent Raman Scattering) microscopy is an umbrella term for label-free methods that image biological structures by exploiting the…

Leica Science Lab
Drosophila melanogaster fruitflies perching on the brim of a bowl of sour dough and waiting for their chance. Image Courtesy: Ursula Gönner, Dolgesheim (Germany).

Visualize developmental patterns in Drosophila

The marvelous complexity of life is perhaps the greatest source of fascination within the biological sciences. Among the most complex subjects within…

Leica Science Lab

Phasor Analysis for FLIM (Fluorescence Lifetime Imaging Microscopy)

The Phasor analysis approach to analyze fluorescence lifetime does not require any fitting. Phasor FLIM (fluorescence lifetime imaging microscopy)…

Leica Science Lab

Coherent Raman Scattering (CRS) Microscopy: A vast and growing range of applications revealed

Leica Microsystems‘ Workshop on Coherent Raman Scattering (CRS) Microscopy attracted 30 enthusiastic participants from all over the world to beautiful…

Leica Science Lab