A historically close collaboration with the scientific, medical, and industrial communities is the key to Leica Microsystems’ tradition of innovation. Drawing on users’ ideas and developing solutions tailored to meet their requirements, the company continually sets new standards in markets it serves. This also applies to the services Leica Microsystems provides customers with: The company offers expert technical services, but also application support for all application-related questions.
170 Years of Leica History
The history of Leica Microsystems is closely related to the world-renowned brands Leitz and Leica. The origin of the company dates back to 1849 when a family business for optics was founded in Wetzlar, Germany. Over the last century it has developed into a global success story with a worldwide reputation. For 170 years, Leica Microsystems has helped shape the future and continues to do so today with its latest digital innovations enabling new insights for research, medical, and industrial applications.
Widefield Visualization of 3D Biologically Relevant Specimens Transformed
The THUNDER Imagers enable users to visualize clearly in real time fine details even deep inside thick specimens of biologically relevant models, e.g., model organisms, tissue sections, and 3D cell cultures. The Imagers eliminate the out-of-focus haze that clouds the view of thick specimens when using camera-based fluorescence microscopes. This performance advantage is achieved with a new opto-digital method created by Leica Microsystems called Computational Clearing.
Redefining the Detection Limit for Confocal Imaging
LIGHTNING extracts valuable image information from previously unseen or inaccessible fine structures and details, expanding imaging capabilities both in the classic confocal range and beyond the diffraction limit, down to 120 nm.
Lifetime imaging in an instant
The SP8 FALCON (FAst Lifetime CONtrast) system can record lifetime contrast 10x faster than previous solutions. This lifetime information lets researchers monitor interactions between proteins in living cells. Additionally, it provides extra contrast to clearly separate a multitude of fluorophores.
Augmenting intraoperative reality
The ARveo digital augmented reality neurosurgical microscope provides surgeons with extensive visual information to empower their intraoperative decision-making. The microscope features groundbreaking GLOW AR digital technology, which combines white light with fluorescence for a single, precise view of the surgical site. GLOW800 AR fluorescence, the first AR modality powered by GLOW AR technology is available fully integrated into ARveo. In combination with ICG, GLOW800 allows surgeons to observe cerebral anatomy in natural color, augmented by a real-time view of blood flow. This is particularly useful in AVM or aneurysm surgeries. The ARveo also integrates digital imaging from IGS systems and endoscopes, as well as allowing surgeons to work “heads-up” looking at a large 4K 3D monitor.
Routine tasks in the cell culture lab become digitized
PAULA (Personal AUtomated Lab Assistant) helps to speed up daily cell culture tasks and standardize the results to improve the downstream workflow. It is configured to stay by your cells on any lab bench or even directly in an incubator.
Get Quality Serial Sections for Array Tomography Fast
ARTOS 3D marks a new level of quality and speed for ultramicrotome sectioning. ARTOS 3D automatically produces ribbons of extremely consistent, thin sections (nanometer range thickness) for array tomographic 3D image reconstruction of the specimen.
Helping surgeons see more, simply
With the launch of the PROvido multidisciplinary microscope Leica Microsystems enhances intraoperative visualization in a broad range of surgical applications. PROvido features exclusive FusionOptics technology from Leica Microsystems, which was previously only available in premium microscope solutions. Surgeons can now see a larger area in full focus and benefit from less interruptions through time consuming refocusing. The top-of-the-line optics and illumination combined for the first time in a responsive, stable floor stand, allow surgeons to see more, simply.
The world‘s first tunable deep imaging solution
With the launch of the all new SP8 DIVE system Leica Microsystems offers the world’s first spectrally tunable solution for multi-color, multiphoton deep tissue imaging. Equipped with 4Tune, a tunable, non-descanned detection system, the SP8 DIVE offers you unlimited flexibility and enables you to develop new multicolor deep in vivo experiments. DIVE stands for Deep In Vivo Explorer and enables researchers to capture up to four fluorophores simultaneously and an unlimited number of fluorophores sequentially. The ability to visualize complex biological processes in living tissues over time is key for driving research in the fields of neurosciences, cancer and inflammatory diseases.
Find, observe and interact with living cells like never before
Whether you need to precisely follow the development of a single cell in a dish, screen through multiple assays, obtain single molecule resolution, or tease out behaviors of complex processes, a DMi8 S system will enable you to see more, see faster, and find the hidden to find the missing link. The DMi8 S imaging solution from Leica provides 5x more speed, and an increased viewing area up to 10,000x. This can be combined with the new photomanipulation scanner to activate, ablate, and bleach within one experiment. For super resolution and nanoscopy, the Infinity TIRF has been added allowing simultaneous multi-color imaging with single molecule resolution. Opening up the next chapter in widefield imaging.
Preparing the ground for future innovations:
Leica Microsystems exclusively licensed SCAPE microscopy for Life Science applications from Columbia University, a technique for fast 3D imaging of living samples with a sheet of light – which complements own IP and developments as well as its exclusive license of Oblique Plane Microscopy (OPM) from Imperial College.
Worlddidac Award for Leica EZ4 W educational stereo microscope:
The Leica EZ4 W which transfers HD images directly to students' mobile devices has been recognized with the prestigious Worlddidac Award, an award that honors outstandingly innovative educational products or solutions.
New image injection technology guides surgeons:
CaptiView technology injects images from image-guided surgery (IGS) software into the microscope eyepieces. Surgeons can fully concentrate on their patient, have all the data in front of their eyes and do not need to look up during the procedure.
Helping researchers understand life-sustaining processes:
The first High Pressure Freezer with integrated light stimulation is a technology so precise that researchers can start asking new questions – and will be able to get answers.
Leica Microsystems acquires Optical Coherence Tomography (OCT) company Bioptigen:
The contact-free imaging method aids ophthalmologists and researchers in the diagnosis of physiological and pathologic conditions of the eye.
Wi-Fi-capable microscopy instruments help increase student learning time:
The Leica EZ4 W educational stereo microscope with built-in wireless camera and the Leica ICC50 W digital camera transfer HD images directly to students' mobile devices.
Nobel Prize for Stefan Hell, father of super-resolution microscopy:
Stefan Hell was awarded the Nobel Prize in Chemistry for the development of super-resolved fluorescence microscopy. In collaboration with Leica Microsystems, this principle was translated into the first commercially available STED microscope.
Two awards for the Leica TCS SP8 STED 3X:
The Scientist Top 10 Innovations Award and R&D 100 Award recognize the super-resolution microscope as one of the innovations that will change the way life scientists work.
Supporting surgeons in visualization:
The surgical microscope Leica M530 OH6 is equipped with technology to enable surgeons to see better into deep, narrow cavities.
Building-block concept for inverted research microscope:
Researchers can build their Leica DMi8 microscope fully modularly. The platform can be adapted to their needs any time – a big difference to former instruments.
Microscopy in Outer Space:
Astronaut Koichi Wakata of the Japan Aerospace Exploration Agency used the inverted research microscope Leica DMI6000 B to carry out live cell experiments at the International Space Station.
Award for Leica SR GSD 3D super-resolution microscope
Enabling scientists to visualize and study cellular structures and processes down to the molecular level, the instrument was voted among the Top 10 Innovations 2013 for laboratories and research.
Integrated 3D visualization for neurosurgeons:
First surgical microscopes with integrated TrueVision 3D technology enable an entire operating team to see what the surgeon sees without the need for a separate cart, thus saving space in the operating room.
Leica Biosystems and Leica Microsystems strengthen market position in Brazil:
Acquisition of Aotec, distributor for more than 25 years moves presence in Latin America forward.
2012 MX Award for Leica Microsystems headquarters:
For its switchover to Kanban systems, Leica Microsystems Operations in Wetzlar, Germany, won the Manufacturing Excellence award for logistics and operational management.
Three awards for Leica GSD super-resolution microscope:
R&D magazine with its R&D100 awards for excellence in technological innovation, one of the three related "Editor's Choice Awards", and the Top Ten Innovations Awards 2012 by US American magazine Microscopy Today.
Enabling new discoveries:
The Leica TCS SP8 confocal microscope combines high-performance optics, the fastest true confocal scanner and the most sensitive detection system available, to enable researchers to uncover life's secrets.
Learn, share, contribute. Science Lab goes live:
Science Lab is the knowledge portal on microscopy and EM sample preparation. Articles, interviews, tutorials, and webinars help users with interesting and hands-on information. By 2016, Science Lab has grown to an online resource with more than 600 articles.
2011 MX Award for Leica Biosystems Nussloch:
Leica Biosystems scores in the customer focus category of the Manufacturing Excellence (MX) Award 2011.
Classroom in HD:
Students and teachers can now view microscope images in HD quality during microscopy classes which enables them to detect more detail in the images.
Award for Remote Care Service Concept:
Leica Microsystems received a gold M2M Value Chain award with Axeda Corporation honored as its enabler at the annual Connected World Conference.
Kavo Dental and Leica Microsystems cooperate for dental microscopes.
Frost & Sullivan Tissue Diagnostics award:
Leica Biosystems receives the North American Product Strategy Award in Tissue Diagnostics by research and consulting firm Frost & Sullivan.
Exclusive license for a new generation of optical microscopes:
Max Planck Innovation grants exclusive license for the new