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THUNDER Imaging Systems

Decode 3D biology in real time*

It’s time to tackle your most pressing scientific problems with more relevant models and better physiology. Until today three-dimensional imaging of model organisms, tissue sections and 3D cell cultures like organoids was not possible with the same ease of use, throughput, speed and sensitivity that you know from two-dimensional imaging with your preferred camera-based fluorescence microscope. The out-of-focus blur introduced by widefield microscopes restricted their use to thin two-dimensional samples.

Leica Microsystems introduces a new class of instrument designed specifically for high-speed, high-quality imaging of thick three-dimensional specimens: THUNDER Imagers

Once you see the results from a THUNDER Imager, you will want to retire any standard fluorescence, structured illumination, or spinning disc confocal microscope in your lab.

*in accordance with ISO/IEC 2382:2015

Simply get in touch!

Our experts on solutions for THUNDER imaging systems are happy to help you with their advice.

See through the haze

THUNDER Imagers remove the out-of-focus blur that comes with three-dimensional samples through Computational Clearing, an exclusive new breakthrough technology. Enjoy image quality which, until now, was only possible with confocal microscopy.

You are enabled to benefit from the ease of use, speed and sensitivity of a widefield system to decode 3D biology of thick specimen in real time.

Standard Fluorescence
THUNDER Imager

HeLa cell spheroid stained with Alexa Fluor 568 Phalloidin (Actin) and YOYO 1 iodide (Nucleus).

High performance for 3D biology

THUNDER imaging systems excel due to:

  • Delivery of benchmark performance and first-rate results for your application
  • Clear view of details in the whole specimen thanks to computational clearing
  • Ease-of-use, speed, and sensitivity, just like with widefield imaging

Very soon you will be able to THUNDER your images!

THUNDER Imager would be especially useful for time lapses, because it allows very fast scanning of big samples in less than 2 minutes, and provides confocal quality images...

Dr. Almary Guerra, Max Planck Institute Bad Nauheim, Germany