Contact & Support

Sample Preparation for Electron Microscopy

When it comes to great results, stunning performance or breakthrough discoveries, you will find one thing that all of them have in common: their precise and careful preparation.

In the field of electron microscopy, perfect sample preparation is a prerequisite and crucial step. Leica Microsystems offers a comprehensive product portfolio for preparation of biological, medical and industrial samples. Concentrating on workflow solutions we provide a product range that is perfectly aligned to all your needs for precise sample preparation in TEM, SEM, and AFM investigations. Each Leica solution consists of several instruments that are perfectly geared to one another to form a seamless workflow for your sample.

Be prepared – for great results in EM Sample Preparation!

Perfect preparation makes the difference between trying and achieving, between failure and success, between results and excellent results. So be prepared for great results with Leica Microsystems!

Electronmicroscopy Sample Preparation Products 22

Filter by Area of Application
EM Cryo CLEM

EM Cryo CLEM

Correlative Light and Electron Microscopy System

EM GP2

EM GP2

Automatic Plunge Freezer

Leica EM VCT500

Leica EM VCT500

Cryo Transfer System

Leica EM ACE200

Leica EM ACE200

Low vacuum sputter and carbon thread coater

Leica EM ACE900

Leica EM ACE900

High-End EM Sample Preparation Freeze Fracture System

Leica EM CTD

Leica EM CTD

Fast, Reliable Cryo Tool Drying for Efficient Cryo EM workflow

Leica EM FC7

Leica EM FC7

Cryochamber for Leica EM UC7 and EM UC6

Leica EM AFS2

Leica EM AFS2

Freeze Substitution and Low Temperature Embedding System for Light and Electron Microscopy

Leica EM TP

Leica EM TP

Automated routine tissue processor

Leica EM AC20

Leica EM AC20

Automatic contrasting instrument for ultrathin sections

Featured image

Cross Section Surface

Cross Section Surface, Pre Paid Card RuO4stained, sectioned with diamond knife at room temperature, treated with a special plasma etching device, SEM image.

Follow us on Instagram

News

Latest Science Lab Articles

18. April 2019 Image Gallery: THUNDER Imager

To help you answer important scientific questions, THUNDER Imagers eliminate the out-of-focus blur that clouds the view of thick samples when using…

15. October 2018 High Resolution Array Tomography with Automated Serial Sectioning

The optimization of high resolution, 3-dimensional (3D), sub-cellular structure analysis with array tomography using an automated serial sectioning…

03. May 2018 Visualization of DNA Molecules

Precise low angle rotary shadowing with heavy metals (like platinum) can be used in transmission electron microscopy (TEM) to observe molecular…

11. December 2017 Free Webinar On-Demand: Mechanical pre-preparation and ion milling for SEM observation

See how the unique combination of pre-preparation system and ion milling system makes fast site specific sample preparation for Scanning Electron…

13. December 2016 Correlative Cryo-Fluorescence and Cryo-Scanning Electron Microscopy as a Straightforward Tool to Study Host-Pathogen Interactions

Correlative light and electron microscopy is an imaging technique that enables identification and targeting of fluorescently tagged structures with…

01. March 2016 Imaging of Host Cell-bacteria Interactions using Correlative Microscopy under Cryo-conditions

Pathogenic bacteria have developed intriguing strategies to establish and promote infections in their respective hosts. Most bacterial pathogens…

04. June 2015 Correlative In-Resin Super-Resolution and Electron Microscopy Using Standard Fluorescent Proteins

We introduce a method for correlative in-resin super-resolution fluorescence and electron microscopy (EM) of biological structures in mammalian…

28. May 2015 Correlative Light and Electron Microscopy – Get Your Free CLEM e-Book for Download

The urge to go deeper into the microscopic world has led researchers to combine the versatility of the light microscopy (LM) with the resolution power…

24. April 2015 Correlating Intravital Multi-Photon Microscopy to 3D Electron Microscopy of Invading Tumor Cells Using Anatomical Reference Points

Cancer research unsing multiphoton microscopy and 3D electron microscopy. Correlative microscopy combines the advantages of both light and electron…

06. March 2015 Customized Patterned Substrates for Highly Versatile Correlative Light-Scanning Electron Microscopy

Correlative light electron microscopy (CLEM) combines the advantages of light and electron microscopy, thus making it possible to follow dynamic…