![[Translate to chinese:] Spheroid stained with Cyan: Dapi nuclear countertain; Green AF488 Involucrin; Orange AF55 Phalloidin Actin; Magenta AF647 CK14.](/fileadmin/_processed_/6/8/csm_Spheroid_stained_with_Cyan_4color_overlay_76cb6e4d04.jpg "[Translate to chinese:] Spheroid stained with Cyan: Dapi nuclear countertain; Green AF488 Involucrin; Orange AF55 Phalloidin Actin; Magenta AF647 CK14.")
![[Translate to chinese:] Hepatocellular Carcinoma with 13 biomarkers shown – Beta-Catenin, CD3D, CD4, CD8a, CD31, CD44, CD163, DAPI, PanCK, PCK26, PD1, SMA, and Vimentin.](/fileadmin/_processed_/5/b/csm_Hepatocellular_Carcinoma_13_Markers_Zoom2_bc27c21cf2.jpg "[Translate to chinese:] Hepatocellular Carcinoma with 13 biomarkers shown – Beta-Catenin, CD3D, CD4, CD8a, CD31, CD44, CD163, DAPI, PanCK, PCK26, PD1, SMA, and Vimentin.")
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Discover how Multiplexed Bioimaging can Advance Cancer Research
Explore multiplexing with up to 60 biomarkers, enabling advanced tumor imaging approaches to gather precise, spatially-resolved single-cell data that helps enhance cancer research and clinical…
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Spatial Biology: Learning the Landscape
Spatial Biology: Understanding the organization and interaction of molecules, cells, and tissues in their native spatial context
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![[Translate to chinese:] Branched organoid growing in collagen where the Nuclei are labeled blue. To detect the mechanosignaling process, the YAP1 is labeled green.](/fileadmin/_processed_/a/e/csm_Branched_organoid_growing_in_collagen_083254eb44.jpg "[Translate to chinese:] Branched organoid growing in collagen where the Nuclei are labeled blue. To detect the mechanosignaling process, the YAP1 is labeled green.")
检查癌症类器官的发展进程
德国慕尼黑工业大学的Andreas Bausch实验室研究细胞和生物体中不同结构和功能形成的细胞和生物物理机制。他的团队设计了新的策略、方法和分析工具，以量化微米和纳米等级的发展机制和动态过程。关键研究领域包括干细胞和类器官，从乳腺类器官到胰腺癌类器官，以更好地了解疾病模型。
![[Translate to chinese:] Cell counts for each biomarker were divided by total number of cells to give a percentage of biomarker positive cells out of total cells for each biomarker.](/fileadmin/_processed_/5/3/csm_Cell_counts_for_biomarkers_with_Cell_DIVE_ee648b397a.jpg "[Translate to chinese:] Cell counts for each biomarker were divided by total number of cells to give a percentage of biomarker positive cells out of total cells for each biomarker.")
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![[Translate to chinese:] PDAC Multiplexed imaging of CST panels enables an examination of immune cell components in pancreatic ductal adenocarcinoma (IPDAC) tissue on a single slide.](/fileadmin/_processed_/a/d/csm_Pancreatic_ductal_adenocarcinoma_tissue_3d61c18a2d.jpg "[Translate to chinese:] PDAC Multiplexed imaging of CST panels enables an examination of immune cell components in pancreatic ductal adenocarcinoma (IPDAC) tissue on a single slide.")
表征肿瘤环境以揭示洞察和空间分辨率
肿瘤环境的表征可以为癌症进展和潜在治疗靶点提供更深入的见解。我们已经使用来自Cell Signaling Technology（CST）的各种IHC验证抗体，在胰腺癌的Cell DIVE研究中验证了30多种偶联抗体。
![[Translate to chinese:] Cancer cells](/fileadmin/_processed_/6/b/csm_Cancer_cells_0188d06359.jpg "[Translate to chinese:] Cancer cells")
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![[Translate to chinese:] Pancreatic ductal adenocarcinoma tissue section imaged with Cell DIVE](/fileadmin/_processed_/f/8/csm_Pancreatic_ductal_adenocarcinoma_tissue_section_teaser_eae5765765.jpg "[Translate to chinese:] Pancreatic ductal adenocarcinoma tissue section imaged with Cell DIVE")
多重成像的类型、优势和应用
与传统显微镜相比，多重成像技术能观察到更多的生物标记物，是一种新兴的、令人兴奋的从人体组织样本中提取信息的方法。通过同时观察多种生物标记物，可以协同探索以前只能单独探索的生物通路，并识别和探测复杂的组织和细胞表型。目前已有许多不同的多重成像方法，每种方法都采用不同的方法来实现更高的复杂性。