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Life Science Research

Leica Microsystems’ Life Science Research Division supports the imaging needs of the scientific community with advanced innovation and technical expertise for the visualization, measurement and analysis of microstructures.

Our strong focus on understanding scientific applications puts Leica Microsystems’ customers at the leading edge of science.

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Microscopes and Imaging systems for Life Science Research 54

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THUNDER Imager Model Organism

The THUNDER Imager Model Organism allows fast and easy 3D exploration of whole organisms for developmental or molecular biology research.

THUNDER Imager 3D Live Cell & 3D Cell Culture & 3D Assay

THUNDER Imagers provide you with a solution for advanced 3D cell culture assays, whether you want to study stem cells, spheroids, or organoids.

Leica EM Cryo CLEM set based on Leica DM6 FS

EM Cryo CLEM

Correlative Light and Electron Microscopy System

THUNDER Imager Tissue

The THUNDER Imager Tissue allows real-time fluorescence imaging of 3D tissue sections typically used in neuroscience and histology research.

High Speed High Resolution Monochrome Fluorescence sCMOS Camera Leica DFC9000

Leica DFC9000

4.2 MP cooled monochrome fluorescence scmos camera for advanced applications like high-speed live cell imaging, FRAP, and ratio measurement

2.8 MP Color Microscope Camera Leica DFC7000 T

DFC7000 T and DFC7000 GT

Cooled 2.8 megapixel digital microscope cameras

Confocal Laser Scanning Microscope SP8 LIGHTNING

SP8 LIGHTNING

Super-resolution live cell imaging in multicolor

Histological section from cat eye. Simultaneous spectral (grey) and FLIM (color) confocal imaging reveals contrast by lifetime. Acquisition and visualization using SP8 FALCON and LAS X software.

SP8 FALCON

The contrast is clear. Lifetime imaging in an instant

Maximum information from each specimen with LIGHTNING

LIGHTNING

The maximum of information from each specimen

Software platform for life science applications

LAS X Life Science

Software platform for life science applications

Automatic Plunge Freezer EM GP2

EM GP2

Automatic Plunge Freezer

Leica M205 FCA & Leica M205 FA

(Semi)-automated fluorescence stereo microscopes

Leica TCS SP8 DLS

Leica TCS SP8 DLS

Combining Light Sheet and Confocal

Leica DM4 B & DM6 B

Increase work efficiency with Leica DM4 B & DM6 B upright digital research microscopes.

Ergonomic microscope system Leica DM2500 LED for demanding tasks in life science applications

Leica DM2500 & DM2500 LED

Ergonomic optical microscope systems for routine and research applications

The Leica DM1000 LED combines the advantages of a fully ergonomic system microscope with innovative LED illumination, and unlimited possibilities in mobile use.

Leica DM1000 LED

Uniquely ergonomic system microscope with LED illumination

EM Sample Preparation Freeze Fracture System Leica EM ACE900

Leica EM ACE900

High-End EM Sample Preparation Freeze Fracture System

Leica EM CTD (accessories not included)

Leica EM CTD

Fast, Reliable Cryo Tool Drying for Efficient Cryo EM workflow

Fluorescence Microscope Camera Leica DFC3000 G

Leica DFC3000 G

1.3 MP monochrome camera for basic fluorescence applications such as documentation of fixed, immunostained samples

Leica HyD for photon counting

Leica HyD

The hybrid detector for super-sensitive imaging and photon counting

Infinity Scanner

Multispectral Photomanipulation Module

Infinity TIRF

Multicolor advanced TIRF module

Inverted Microscope for Cell and Tissue Culture

Leica DMi1

Entry level inverted microscope

Leica motCORR Microscope Objective

Leica motCORR Objectives

Fast adjustment to varying RI for best optical performance in 3D

Inverted Laboratory Microscope with LED Illumination

Leica DM IL LED

Inverted Laboratory Microscope with LED Illumination

Leica EM FC7 ‐ Cryochamber for Leica EM UC7 and EM UC6

Leica EM FC7

Cryochamber for Leica EM UC7 and EM UC6

Uniquely Ergonomic System Microscope Leica DM1000

Leica DM1000

Uniquely Ergonomic System Microscope

The Leica EM TP Automated Routine Tissue Processor

Leica EM TP

Automated routine tissue processor

Laser Microdissection Microscope Leica LMD6 & Leica LMD7

Leica LMD6 & LMD7

Laser Microdissection enables users to isolate specific single cells or entire areas of tissue.

Leica DM6 FS fixed stage fluorescence microscope

Leica DM6 FS

Fixed Stage Microscope for Electrophysiology and in vivo Imaging

Leica TL4000 BFDF

Transmitted Light Base For Brightfield and Darkfield Applications Absorbs Shock and Vibrations for High Quality Imaging

Simultaneous use of 1X stereo objective and 10X or 20X compound objective for high resolution imaging.

Leica FluoCombi III

Fluorescence stereomicroscope accessory

LED Multi Contrast Illumination LED3000 MCI

Leica LED3000 MCI

LED Multi Contrast Illumination for Routine Stereo Microscopes

The Leica LAS X Widefield System performs workflow-guided advanced image analysis and includes a full range of image enhancement tools.

LAS X Widefield Systems

Fluorescence Microscope System for Advanced Imaging and Analysis

The uniquely ergonomic system microscope Leica DM3000 boosts cytology and pathology workflows thanks to its intelligent automation.

Leica DM3000 & DM3000 LED

Uniquely Ergonomic System Microscopes With Intelligent Automation

Featured image

Tile mouse scan

Tile scan image of mouse brain tissue section with multicolor immunofluorescent labeling acquired with the DMi8 S system.

Light Microscopes

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Wound healing with PAULA

How can PAULA help streamline the workflow for my wound healing assay?

Application for wound healing assays

LMD Software

New LMD Software 8.2.1 for Laser Microdissection

Leica Microsystems has now released version 8.2.1 of the LMS software for Laser Microdissection microscopes. Laser Microdissection is used to dissect...

MDCK cells, Phase Contrast, red outlines are marking the cell borders. Courtesy of Prof. Ralf Jacob, University of Marburg, Germany

Confluency Check with PAULA Cell Imager

Monitor your cell culture around the clock with PAULA and know the perfect time-point for your experiment

Leica Microsystems and University Mainz cooperate for a Microscopy Reference Center

New center with focus on innovation for light microscopy is located at University Medical Center in Mainz, Germany

Free Booklet: EM Sample Preparation Workflow Solutions for Life Science

Find out how Leica supports your workflow and learn about other similar workflows. This publication provides a collection of most frequently used...

SP8 LIGHTNING confocal microscope

Next generation confocal platform for super-resolution live cell imaging in multicolor

Detailed observations of fast biological processes with the SP8 LIGHTNING

Save time for 2D and 3D analysis

LAS X.next, a streamlined software user interface for the DVM6 digital microscope

Cleanliness Expert software - New user interface

Easy to use and fast to adapt. Learn about the new user interface for the Cleanliness Expert software. You will see that this software interface is...

UC San Diego and Leica Microsystems Establish Center of Excellence in Microscopy

The new Center will support a combined mission to educate the next generation of scientists and drive new scientific discoveries

Winners of the Human Protein Atlas Image Classification Announced

Kaggle Competition Prize Money Sponsored by Leica Microsystems

Laser Microdissection Publication List

This monthly updated reference list demonstrates the major application fields for laser microdissection in life science research.

Leica Science Lab

Where to go? Cellular Migration requires coordinated Transitions of Actin Cortex

Plants, Bacteria, and Fungi possess a rigid cell wall that protects the cell and gives it shape. Animal cells, such as mammalian cells, have no outer…

Leica Science Lab
Cover glomerulus

The Guide to STED Sample Preparation

This guide is intended to help users optimize sample preparation for stimulated emission depletion (STED) nanoscopy, specifically when using the TCS…

Leica Science Lab

Image Gallery: THUNDER Imager

To help you answer important scientific questions, THUNDER Imagers eliminate the out-of-focus blur that clouds the view of thick samples when using…

Leica Science Lab

Analysis of Tissue Sections Assisted by Fluorescence Laser Microdissection

Lectin microarray (LMA) is a highly sensitive technology used to obtain the global glycomic profiles of endogenous glycoproteins in biological samples…

Leica Science Lab

How can PAULA help streamline the workflow for my wound healing assay?

The wound healing assay, often used as a synonym for scratch assay or migration assay, is an important tool for the evaluation and measurement of cell…

Leica Science Lab

THUNDER Technology Note

So far, widefield microscopy was not suitable to image larger volumes, since the contrast of the recorded fluorescence image is reduced by the…

Leica Science Lab
MDCK cells, Phase Contrast, red outlines are marking the cell borders. Courtesy of Prof. Ralf Jacob, University of Marburg, Germany

Confluency Check with PAULA Cell Imager

Many cell-based experiments require cells in a certain state. This can include their morphology,  fluorescent protein expression, and the confluency…

Leica Science Lab

Extending Nanoscopy Possibilities with STED and exchangeable fluorophores

When it comes to STED Nanoscopy, keeping high signal-to-noise is key to achieve the best possible resolution in fixed and living cells. This can be…

Leica Science Lab

Webinar: See More Than Just Your Image

Despite the emergence of new imaging methods in recent years, true 3D resolution is still achieved by Confocal Laser Scanning Microscopy (CLSM).…

Leica Science Lab