Widefield Super-resolution with Ground State Depletion (GSDIM) Leica SR GSD
Resolve down to 20 nm with GSDIM
GSDIM is a scientifically proven method using a wide range of standard fluorochromes.
Leica Microsystems are pioneers in super-resolution microscopy. The 2007 introduction of the Leica TCS STED heralded a new era of products that break the barriers of diffractionlimited imaging.
Based on the highly regarded Leica AM TIRF MC system and the Leica DMI6000 B inverted microscope, the Leica SR GSD harnesses an imaging technique known as Ground State Depletion (GSDIM).
Your Advantages
 |
 |
Maximum resolution down to 20 nmBased on GSDIM technology, the new Leica SR GSD surpasses the resolution limits previously set by other super-resolution systems. GSDIM and STED are patented by Stefan Hell of the Max Planck Institute Göttingen, Germany, and exclusively licensed to Leica Microsystems. Image above: Ptk2-cells. |
Standard fluorochromes can be used – no need to change your protocolsThe workflow for GSD is based on standard immunostaining techniques and integrates perfectly into existing workflows for fluorescence microscopy. Image above: MDCK cells |
The SuMo stage, with suppressed motion technology, minimizes drift for accurate localization of moleculesThe Leica SR GSD introduces brand new technology in drift compensation, which puts the maximum system drift below the resolution during acquisition. This makes it possible to observe the super-resolution image as it is being acquired. |
Online super-resolution image projection – see your results as they are acquiredThe Leica SR GSD offers online image projection of the super-resolution image. During acquisition, the user sees the image building up online. This feature puts you in full control of your experiment – you can decide to stop or continue the image acquisition to achieve a satisfying result. |
 |
 |
Full application flexibility offered by combining super-resolution with TIRF and epifluorescence on a multi-purpose live cell imaging systemThe Leica SR GSD puts the power of high resolution into a user-friendly system, alongside a full range of widefield microscopy applications. The workstation allows you to perform your everyday experiments, from high-speed imaging to time-lapse to TIRF, whilst expanding your imaging into the sphere of super-resolution. |
Direct contact, consulting and support
- Find your local Leica Microsystems partner
- Get quotes - profit from owning a Leica Microsystems product
- Tailored advice - learn about the benefits Leica Microsystems provides for your work situation
Images Leica SR GSD
Related Products
|
|
|
|
| Leica DMI6000 B Fully Automated Inverted Research Microscope for Biomedical Research | Leica TCS STED Super-Resolution Microscope | Leica TCS STED CW The Fast Track to Super-Resolution | Leica AM TIRF MC True MultiColor Laser TIRF |