News for Leica DM6000 B

Scanning Stage for Leica DM4000-6000 B Upright Research Microscopes

New motorized scanning stage 100x100 mm, developed especially for applications with upright research microscopes Leica DM4000-6000 B for automatic and high-precision positioning of samples

• Flat design due to lowered motor axis
• For reflected light/fluorescence and transmitted light applications
• New stage insert for 2 glass slides 3”x 2” (76 x 52 mm) for precise holding
• Motor cable connection located ergonomically on the back right side
• Integrated in Leica Microsystems Software and control units
  (can be operated by Leica Software/SmartMove/STP6000)
• Adjustable limit switches for individual adjustment of the travel range of the stage

Upright Research Microscopes from Leica Microsystems

Ariol on Leica SCN400 combines leading scanning technology with advanced analysis experience. A perfect pathology workstation for the assessment of clinical brightfield and fluorescent biomarkers.

Leica Microsystems Extends its Product Portfolio in Virtual Microscopy

Wetzlar, Germany. With its unprecedented scanning speed and top-quality on-screen imaging, the Leica SCN400 Slide Scanner has already set new standards in virtual imaging. Through the acquisition of Genetix Ltd. at the beginning of this year, Leica Microsystems is now able to considerably expand its solutions offering. With the software solutions Ariol and SlidePath, Leica Microsystems now adds the ability to store, manage, analyze, and report on digital images created with the Leica SCN400 Slide Scanner or the Leica DM6000 B Research Microscope.

High throughput solution for in vitro diagnostics: Ariol on the Leica SCN400

Combining Ariol with the Leica SCN400 Slide Scanner provides a complete solution for labo­ratories dealing with a high volume of slides. The product is a high throughput solution for biomarker assessment. Ariol on Leica SCN400 combines leading scanning technology with advanced analysis experience, giving the customer the good feeling to get the best product in all respects. From sample to result, Leica Microsystems is striving to provide the total histology solution and be the pathologist’s integrated partner in every step of the process.

Web-enabled image handling and e-learning: SlidePath on the Leica SCN400

SlidePath software on the Leica SCN400 Slide Scanner opens the world of image and data handling in a flexible and powerful web-enabled solution. With the Digital Image Hub (DIH) module from SlidePath, Leica Microsystems provides the complete end-to-end solution for virtual microscopy, especially optimized to provide rapid whole slide imaging coupled with an online management solution that can handle multiple formats including DICOM and other standard imaging formats. DIH is also designed for use in research under the guideline of regulatory bodies, such as preclinical research or toxicological studies, which profit from multiple features especially designed for this customer group.

Furthermore, DIH can be combined with diverse specialized software modules from SlidePath, such as a special module for TMA management – called OpTMA – or the Digital SlideBox, which provides tools for e-learning.

Pathology workstation for in vitro diagnostics: Ariol on the Leica DM6000 B

The in vitro diagnostics software Ariol on the Leica DM6000 B Research Microscope creates a perfect pathology workstation for the assessment of clinical brightfield and fluorescent biomarkers. The system integrates seamlessly into the pathologist’s workflow with the means to digitize whole slides or regions of interest. With this solution customers enter the world of Virtual Microscopy while staying with the highest possible flexibility in terms of hardware configurations. The modules Hersight, ERsight, PRsight and PathVysion are available in the US for in vitro diagnostic use.

• Press Release Virtual Microscopy (English)
• Press Release Virtual Microscopy (German)

Leica Microsystems is a leading global designer and producer of innovative, high-tech, precision optical systems for the analysis of microstructures. It is one of the market leaders in each of its business areas: Microscopy, Confocal Laser Scanning Microscopy with corresponding Imaging Systems, Specimen Preparation, and Medical Equipment.

The company manufactures a broad range of products for numerous applications requiring microscopic imaging, measurement, and analysis. It also offers system solutions for life science including biotechnology and medicine, research and development of raw materials, and industrial quality assurance. The company is represented in over 100 countries with 13 manufacturing facilities in 8 countries, sales and service organizations in 19 countries and an international network of dealers.

The international management is headquartered in Wetzlar, Germany.

Kidney section (mouse). Maximum projection of a stack of 65 single images. Green: Glomeruli and convoluted tubules (wheat germ agglutinin Alexa Fluor® 488); blue: cell nuclei (DAPI).

The Smart Solution for Superior Contrast in Fluorescence Imaging

Wetzlar, Germany. Resolution and contrast are crucially important for fluorescence applications in widefield microscopy. Undesired haze effects that reduce contrast can be minimized by using the smart principle of structured illumination. The result: fluorescence images with excellent contrast, superb axial resolution and ultra-sharp 2D sections of the specimen.

Intelligent Structured Illumination Microscopy from Leica Microsystems uses the proven OptiGrid® technique. Working in harmony with Leica’s superior quality optics, the aperture diaphragm integrated with the fluorescence light path also enhances contrast. The automatic focus function of the OptiGrid® keeps the grid structure in focus, from UV to IR light.

A unique feature of this development is that the same OptiGrid® module can be used both for upright and for inverted Leica research microscopes. Furthermore, there is no need to change the grid, as one optimized grid covers all magnifications from 10x to 100x, which offers convenience, avoids errors, and saves valuable time.

Intelligent Structured Illumination Microscopy from Leica Microsystems gives you a complete system from a single source: The OptiGrid® module integrated with Leica research microscopes is controlled by intuitive Leica MM AF software and complemented by a wide selection of fluorescence cameras.

Leica Structured Illumination is available for the inverted research microscopes Leica DMI4000 B and DMI6000 B, and the upright research microscopes Leica DM5000 B, DM5500 B and DM6000 B.

• Leica Structured Illumination product webpage
• Press Release Leica Structured Illumination (English)
• Press Release Leica Structured Illumination (German)

The perfect imaging solution for all scientific research: the new generation Leica Digital Microscopes for biological and materials sciences

The perfect imaging solution for all scientific research: the new generation Leica Digital Microscopes for biological and materials sciences

Wetzlar, Germany. Leica Microsystems introduces an enhanced imaging solution for biological and materials sciences. Quickly and easily capture excellent images and achieve reliable, reproducible research results with the new generation Leica Digital Microscopes. The Leica DM4000 B through DM6000 B series for biological sciences, and the Leica DM4000 M and Leica DM6000 M Digital Microscopes for material sciences and industrial quality analysis, streamlines important work processes. The image brilliance and operational speed of the integrated imaging system are unparalleled in this class of microscope. Leica’s Intelligent Automation, made possible via the most sophisticated control electronics, ensures reproducible, reliable results. New components, such as the external Leica STP6000 SmartTouch Panel, give the researcher a new level of convenient microscope control.

Convenient microscope control

The Leica DM4000 is the only microscope of its class with a status display that shows all settings at a glance and allows individual function modes for specific applications. With the Leica DM5000 through DM6000, the user can set the automated functions using the new Leica SmartTouch color touchscreen, which is built into the stand. As a result, different user profiles can be saved and recalled at the push of a button. With the new, optional Leica STP6000 SmartTouch Panel, the Leica Digital Microscopes can also be operated via remote control. These convenient controls feature the same user interface for direct, intuitive operation as the Leica Application Suite Software (LAS). All motorized modules of the microscopes can also be controlled on the PC via the LAS software.

Save precious time

Working with microscopes has never been so easy. Complex processes can be automated according to individual specifications. In this way the user not only saves a great deal of time during familiarization, but also during his or her daily work. The microscopes can be operated intuitively, and all parameters can be automatically set and reproduced at any time. Leica’s unique method of changing contrast with the push of a button and the fully automated Differential Interference Contrast (DIC) make switching contrast techniques a fast and reliable process.

The perfect integrated system

Each research task has its own unique requirements. The microscope, camera, and LAS software modules for image processing and documentation integrate seamlessly and can be configured to best meet the scientist’s research needs, now and in the future. Due to the harmonized integration of the microscope, digital camera and software, Leica Microsystems offers an all-inclusive solution.

• Press Release Leica DM4000-DM6000 (English)
• Press Release Leica DM4000-DM6000 (German)