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Microscope Cameras for Fluorescence Microscopy

Insights into the structures and dynamics of life

Fluorescence microscopy is essential technique for studying biological processes. Fluorescence can be used to visualize specific subcellular structures in fixed cells, and reveal connections between dynamic processes in live cells and tissues. Without fluorescence labeling, few cellular process can be visualized since most biological samples are almost transparent. A broad range of advanced Live-cell Imaging Techniques can be employed by researchers to probe the complexities of cellular processes. Fluorescence imaging is central to many of these imaging techniques. 

To obtain excellent fluorescence images you need a highly sensitive camera delivering a high signal-to-noise ratio and a large dynamic range resulting in a crisp fluorescence signal. Live-cell imaging often requires a high acquisition speed to capture fast dynamic processes. 

Need Assistance?

Contact a local imaging specialist for expert advice on the right microscope camera for your needs and budget.


Why Fluorescence Cameras from Leica Microsystems?

We base our range of fluorescence cameras on highly sensitive CCD or sCMOS sensors that are ideally suited for low light applications that will capture even weak signals. The majority of our cameras are actively cooled to help reduce noise. We also use sensors with high quantum efficiency so that you can reduce exposure times, protecting your samples from photo-damage.

Monochrome and Color Microscope Cameras

Our monochrome and color cameras are designed for a broad range of applications, from basic tasks such as documentation of immuno-stained samples to advanced demanding live cell imaging applications such as fast time-lapse and FRAP. Our Leica Application Suite (LAS) X software seamlessly integrates our cameras into the microscope system, supporting high-speed triggering.


Jellyfish Aequorea Victoria. Source: Ssblakely, via Wikimedia Commons

The origin of fluorescent proteins

The discovery of fluorescent proteins revolutionized the world of life sciences in the last century and was the key breakthrough technology that permitted the discovery and study of numerous cellular processes. The article traces the history of the fluorescent proteins.

Fluorescent proteins

Introduction to fluorescent proteins and their photospectral characteristics

In the beginning, there was GFP, today there is a whole pallet of fluorescent proteins to work with. Get an introduction to fluorescent proteins and their spectral characteristics in this Science Lab article.