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A Shift of Perspective

The Leica DMi8

Researchers know that a shift of perspective often leads to the most exciting insights. So do we. The Leica DMi8 is the reinvention of inverted microscopy. It is as universal as your ideas, and as individual as your tasks. Find out how a shift to Leica DMi8 will inspire your work.

Life sciences are constantly evolving. At Leica Microsystems, we have created a unique platform that grows with researchers’ needs. The Leica DMi8 tailor-made solutions leave preconfigured microscopes in the past.

JULIAN BURKE PhDChief Scientific Officer, Leica Microsystems

By the way: See more in one go with the Leica DFC9000 sCMOS camera mounted on the Leica DMi8: Together they are a matched set with 19mm field of view on both.

One Platform to Match the Future of Life Sciences

From basic microscopy to high-end imaging – Leica DMi8 grows with your ever-changing needs.

As Universal as Your Ideas

With our Leica DMi8 platform we reinvented inverted microscopy. From simple documentation to advanced imaging – one microscope stand meets all of your research needs. Facilitated by its modular and upgradable design, the Leica DMi8 portfolio goes from manual operation up to fully automated systems capable of advanced imaging.

As Individual as Your Tasks

Your sample is at the center of our focus. The Leica DMi8 is perfectly adapted to the needs of your work. With optimized microscope features, your individual sample will always stay in the spotlight.

Infinity Port Designed for Flexibility

From observation to interaction – Leica DMi8 opens new dimensions for your research

One fluorescence port is good, but two are better. If your scientific interest exceeds standard imaging methods, a single fluorescence port is not enough. The Leica DMi8 enables you to couple a second light source via an additional access point:

The Infinity Port.

Direct access to the infinite light path allows you to connect an additional light source for techniques like FRAP, photo activation, laser ablation, laser tweezing, or optogenetics.

The Solution for Live Cell Experiments

From easy handling to sophisticated analysis – Leica DMi8 and LAS X software team up perfectly with your living samples.

The Leica DMi8 incubation system keeps your cells happy during imaging, while LAS X software controls all acquisition and environmental parameters and makes 3D image analysis, tracking or any other experimental parameters easy to manage.

The Perfect Synergy of Hardware ...

... and Powerful Software.

A Microscope Platform for all Applications –
From Advanced Routine Microscopy to Cutting Edge Research

Come with us on a journey. Find out how the Leica DMi8 will shift your perspective on your application.

Leica DMi8 for Live Cell Imaging

Leica DMi8 for Live Cell Imaging

To get the most information, observation of living samples requires special care and fast image acquisition. Find out more about our configurations for live cell imaging.

Leica DMi8 for Advanced Imaging

Leica DMi8 for Advanced Imaging

Advanced imaging methods call for advanced products. The Leica DMi8 is capable of endlessly sophisticated solutions. Find out more.

Leica DMi8 for Super Resolution

Leica DMi8 for Super Resolution

Our super-resolution system Leica SR GSD 3D utilizes localization microscopy to break the diffraction barrier. With it, lateral and axial resolution are minimized down to 20 nm and 50 nm, respectively.

Leica DMi8 for TIRF

Leica DMi8 for TIRF

Do you want to analyze cellular events at plasma membranes with unprecedented signal-to-noise-ratios? Then TIRF microscopy is the best choice. Click to find out more.

Leica DMi8 for Adherent Cell Injection, Transgenics & IVF

Leica DMi8 for Adherent Cell Injection, Transgenics & IVF

Physical interaction with a cell requires outstanding optical and mechanical quality. See the Leica DMi8 solutions concerning adherent cell injection, transgenics and IVF here.

Leica DMi8 for Screening

Leica DMi8 for Screening

Would you like to screen a large number of samples or conditions? This Leica DMi8 configuration gives you the opportunity to speed up your discoveries and standardize your biological applications easily.

Leica DMi8 for Ratio Imaging

Leica DMi8 for Ratio Imaging

Are you interested in a deeper understanding of life? The Leica DMi8 is suitable for all kinds of quantitative imaging experiments and can shed light on undiscovered physiological phenomena.

Leica DMi8 for Documentation

Leica DMi8 for Documentation

Do you think documentation is tiresome? Let the Leica DMi8 convince you that the opposite is true.

Leica DMi8 for FRAP

Leica DMi8 for FRAP

The Leica DMi8 plus the Leica WF FRAP is an outstanding combination of high speed imaging and fast, accurate FRAP capabilities.

Leica DMi8 for Industry

Leica DMi8 for Industry

No matter if you work in metallography, medical device manufacturing or materials research, speed is essential. Tailor Leica DMi8 to your needs.

Continuity in Quality

The Leica DMi8 is designed and manufactured with the quality you expect from a Leica Microsystems microscope. Brilliant optics, high-grade materials, robust design, ease-of-use down to the smallest details, and a customer-centered service deliver outstanding performance.