Potential of Multiplex Confocal Imaging for Cancer Research and Immunology

Communications, Corporate

October 23, 2023

Potential of Multiplex Confocal Imaging for Cancer Research and Immunology

Expanding the frontiers of multiplex imaging - webinar on-demand

Application example of hyperspectral imaging TNBC_LeGO_primary_tumor.jpg

About the webinar

In this webinar, Cameron Nowell and his colleagues from Monash Institute of Pharmaceutical Sciences will share their experience in multiplex imaging and the results they were able to achieve through clever confocal imaging acquisition, as well as by utilizing other multiplexing modalities such as FLIM.

What you will learn

Key Learnings

how multiplexed imaging can help to understand the spatial relationship between cancer cells and sympathetic nodes within the tumor and metastatic microenvironment.
how using multiplexed imaging to visualize immune cell populations within the colon of neonatal patients with first run disease.
how new technologies on the STELLARIS confocal platform help to extend multiplexing capabilities for life science research.

Webinar abstract

The first example comes from cancer research. It will demonstrate a unique method used in measuring spatial interactions in a tumor microenvironment of a triple-negative breast cancer.

The second example is about how to harness the power of multiplexed imaging to investigate changes to immune cell population size and location within the intestinal wall in patients who are high risk of developing a potentially lethal infection named Hirschsprung Associated Enterocolitis.

After their presentation, we will go in a detailed account of how the STELLARIS confocal platform enables researchers to extend multiplexing capabilities through new and improved technologies: the next generation of White Light Lasers and Power HyD detectors for optimized excitation and emission including the near infrared range, fully integrated lifetime-based imaging approaches (TauSense) and Stimulated Emission Depletion (STED).

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Webinar

Speakers

Cameron Nowell

Microscopist & Image Analyst

Cameron has led the imaging and flow cytometry capabilities at MIPS since its inception 10 years ago. Bringing experience in imaging (optical and electron) along with a range of other lab …

Ashleigh Gould

Research Student - Pharmaceutical Science Hons.

Ashleigh is a final year PhD TBC student studying in the Integrated Neurogenic Mechanisms lab under the supervision of Dr. Daniel Poole, Dr. Simona Carbone, Dr Emily Eriksson (WEHI) and …

Annabel Manoleras

PhD Candidate at Monash Institute of Pharmaceutical Science

Annabel Manoleras completed a Bachelor of Medicinal Chemistry at the University of Technology Sydney in 2019, followed by her Bachelor of Medicinal Chemistry (Honours) at the Children’s …

Taryn Guinan

Senior Applications Specialist at Leica Microsystems

Taryn has a PhD in Materials Science from University of South Australia. Her post doctoral research at Monash University combined imaging with mass spectrometry for small molecule …

Authors

Corporate Communications

Leica Microsystems

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Potential of Multiplex Confocal Imaging for Cancer Research and Immunology

Expanding the frontiers of multiplex imaging - webinar on-demand

About the webinar

What you will learn

Key Learnings

Webinar abstract