THUNDER Imager Model Organism
THUNDER Imaging Systems
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Leica Microsystems
THUNDER Imager Model Organism
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Imaging Organoid Models to Investigate Brain Health
Imaging human brain organoid models to study the phenotypes of specialized brain cells called microglia, and the potential applications of these organoid models in health and disease.
How Microscopy Helps the Study of Mechanoceptive and Synaptic Pathways
In this podcast, Dr Langenhan explains how microscopy helps his team to study mechanoceptive and synaptic pathways, their challenges, and how they overcome them.
Central Nervous System (CNS) Development and Activity in Organisms
This article shows how studying central nervous system (CNS) development in Drosophila-melanogaster embryos expressing a GCaMP calcium indicator in the neurons can be improved with a THUNDER Imager.
Going Beyond Deconvolution
Widefield fluorescence microscopy is often used to visualize structures in life science specimens and obtain useful information. With the use of fluorescent proteins or dyes, discrete specimen…
Fast, High Acuity Imaging and AI-assisted Analysis
The use of state-of-the-art AI systems is pushing image analysis into a new generation. Challenges like the conflict between imaging power and sample integrity are being overcome with THUNDER’s…
Create New Options for Live Cell Imaging
The use of state-of-the-art AI systems is pushing image analysis into a new generation. Challenges like the conflict between imaging power and sample integrity are being overcome with THUNDER’s…
Accurately Analyze Fluorescent Widefield Images
The specificity of fluorescence microscopy allows researchers to accurately observe and analyze biological processes and structures quickly and easily, even when using thick or large samples. However,…
Role of Mucins and Glycosylation in Dry Eye Disease
This article shows how fast, high-contrast, and sharp imaging of stratified human corneal epithelial cells with THUNDER imaging technology for dry eye disease (DED) research allows membrane ridges to…
Optimizing THUNDER Platform for High-Content Slide Scanning
With rising demand for full-tissue imaging and the need for FL signal quantitation in diverse biological specimens, the limits on HC imaging technology are tested, while user trainability and…
Physiology Image Gallery
Physiology is about the processes and functions within a living organism. Research in physiology focuses on the activities and functions of an organism’s organs, tissues, or cells, including the…
Neuroscience Images
Neuroscience commonly uses microscopy to study the nervous system’s function and understand neurodegenerative diseases.
Developmental Biology Image Gallery
Developmental biology explores the development of complex organisms from the embryo to adulthood to understand in detail the origins of disease. This category of the gallery shows images about…
Into the Third Dimension with "Wow Effect"- Observe Cells in 3D and Real-Time
Life is fast, especially for a cell. As a rule, cells should be examined under physiological conditions which are as close as possible to their natural environment. New technologies offer tremendous…
Observing 3D Cell Cultures During Development
3D cell cultures, such as organoids and spheroids, give insights into cells and their interactions with their microenvironment. These 3D cell cultures are playing an increasingly important role for…
Download The Guide to Live Cell Imaging
In life science research, live cell imaging is an indispensable tool to visualize cells in a state as in vivo as possible. This E-book reviews a wide range of important considerations to take to…
Studying Cell Division
Cell division is a biological process during which all cellular components must be distributed among the daughter cells. The division process requires firm coordination for success. Microscopy is…
The Power of Pairing Adaptive Deconvolution with Computational Clearing
Learn how deconvolution allows you to overcome losses in image resolution and contrast in widefield fluorescence microscopy due to the wave nature of light and the diffraction of light by optical…
Improvement of Imaging Techniques to Understand Organelle Membrane Cell Dynamics
Understanding cell functions in normal and tumorous tissue is a key factor in advancing research of potential treatment strategies and understanding why some treatments might fail. Single-cell…
Image Gallery: THUNDER Imager
To help you answer important scientific questions, THUNDER Imagers eliminate the out-of-focus blur that clouds the view of thick samples when using camera-based fluorescence microscopes. They achieve…
From Organs to Tissues to Cells: Analyzing 3D Specimens with Widefield Microscopy
Obtaining high-quality data and images from thick 3D samples is challenging using traditional widefield microscopy because of the contribution of out-of-focus light. In this webinar, Falco Krüger…
Studying Human Brain Development and Disease
Neural spheroids created from human induced pluripotent stem cells (iPSCs) provide effective and novel tools for studying brain development, as well as the underlying pathological mechanisms of…
An Introduction to Computational Clearing
Many software packages include background subtraction algorithms to enhance the contrast of features in the image by reducing background noise. The most common methods used to remove background noise…
Computational Clearing - Enhance 3D Specimen Imaging
This webinar is designed to clarify crucial specifications that contribute to THUNDER Imagers' transformative visualization of 3D samples and improvements within a researcher's imaging-related…
THUNDER Imagers: High Performance, Versatility and Ease-of-Use for your Everyday Imaging Workflows
This webinar will showcase the versatility and performance of THUNDER Imagers in many different life science applications: from counting nuclei in retina sections and RNA molecules in cancer tissue…
Drosophila Testis Niche Stem Cells – Three Color Computational Clearing
Differentiated living beings such as humans, but also a fruit fly or a plant, possess not only the differentiated cells which form specific tissues, but also those cells whose fate is not yet (or only…
Alzheimer Plaques: fast Visualization in Thick Sections
More than 60% of all diagnosed cases of dementia are attributed to Alzheimer’s disease. Typical of this disease are histological alterations in the brain tissue. So far, there is no cure for this…
Real Time Images of 3D Specimens with Sharp Contrast Free of Haze
THUNDER Imagers deliver in real time images of 3D specimens with sharp contrast, free of the haze or out-of-focus blur typical of widefield systems. They can even image clearly places deep inside a…
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라이브 셀 이미징
Leica Microsystems는 단일 현미경 구성 요소에서 완전한 라이브 셀 이미징 솔루션으로 관점을 전환해 현미경, LAS X 이미징 소프트웨어, 카메라 및 전용 타사 구성요소를 완전한 라이브 셀 이미징 시스템에 통합합니다.
형광 현미경법
형광은 주로 높은 감도와 높은 특이성 때문에 생물학적 및 분석적 현미경법에서 가장 일반적으로 사용되는 물리적 현상 중 하나입니다. 연구에 형광 현미경이 어떻게 활용될 수 있는지 확인해보세요.
제브라피시 연구
선별, 분류, 조작 및 이미징 중 최상의 결과를 얻으려면 세부 사항과 구조를 관찰해 다음 연구 단계를 위한 올바른 결정을 내려야 합니다.
탁월한 광학 성능과 우수한 해상도로 유명한 Leica 실체 현미경과 투과광 베이스는 전 세계 연구자들이 선택하는 제품입니다.
신경과학 연구
신경변경 질환에 대해 더 잘 이해하기 위해 노력하고 있거나 신경계 기능을 연구하고 계십니까? 라이카마이크로시스템즈의 이미지 솔루션을 통해 발전을 이룰 수 있는 방법을 알아보세요.
연구 분야의 모델 유기체
모델 유기체는 연구자들이 특정한 생물학적 과정을 연구하기 위해 사용하는 종입니다. 이들은 인간과 유사한 유전적 특성을 가지고 있으며, 유전학, 발달생물학, 신경과학 같은 연구 분야에서 일반적으로 사용됩니다. 유기체 모델은 일반적으로 실험실 환경에서 쉬운 유지와 번식, 짧은 세대 주기 또는 특정 형질이나 질병을 연구하기 위한 돌연변이 생성 능력 때문에…
바이러스 연구
연구의 관심 분야가 바이러스 감염과 질병에 집중되어 있습니까? 라이카마이크로시스템즈의 이미징 및 샘플 준비 솔루션을 통해 바이러스학에 관한 통찰력을 얻는 방법을 알아보세요.
암시야 현미경
암시야 대비법은 재료 시료의 불균일한 특징부 또는 생물학적 표본의 구조로부터 광의 회절 또는 산란을 이용합니다.
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