STELLARIS DLS Digital Light Sheet Microscope

Light Sheet Re-Imagined

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Virtual Reality Showcase for STELLARIS Confocal Microscopy Platform

Take a seat directly next to our experts in front of the microscope, configure various multicolor experiments and see immediately the result. Be part of the highly interactive discovery tour of the…
Virtual Reality Showcase for STELLARIS Confocal Microscopy Platform

Confocal Imaging of Immune Cells in Tissue Samples

In this webinar, you will discover how to perform 10-color acquisition using a confocal microscope. The challenges of imaged-based approaches to identify skin immune cells. A new pipeline to assess…
Confocal Imaging of Immune Cells in Tissue Samples

Wt1 Genes Can Induce a Cardiomyocyte to Epicardial-like Cell Fate Transition

From this study, it was concluded that Wt1 plays a yet undescribed role for cardiomyocyte differentiation by repressing chromatin opening at specific genomic loci and that sustained ectopic expression…
Wt1 Genes Can Induce a Cardiomyocyte to Epicardial-like Cell Fate Transition

Gentle 3D Imaging of Biological Samples

For 3D imaging of biological samples, light sheet microscopy is a powerful and sensitive tool allowing you to measure (sub)cellular dynamics over long periods of time. Meanwhile, confocal microscopy,…
Gentle 3D Imaging of Biological Samples

Multicolor 4D Super Resolution Light Sheet Microscopy

The AI Microscopy Symposium offers a unique forum for discussing the latest AI-based technologies and tools in the field of microscopy and biomedical imaging. In this scientific presentation, Yuxuan…
Multicolor 4D Super Resolution Light Sheet Microscopy

Imaging of Anti-Cancer Drug Uptake in Spheroids using DLS

Spheroid 3D cell culture models mimic the physiology and functions of living tissues making them a useful tool to study tumor morphology and screen anti-cancer drugs. The drug AZD2014 is a recognized…
Imaging of Anti-Cancer Drug Uptake in Spheroids using DLS

Effects of Clearing Media on Tissue Transparency and Shrinkage

This study comprehensively evaluates the effects of different clearing media on tissue transparency and shrinkage by comparing freshly dissected dipteran fly brains with their cleared equivalents.…
Effects of Clearing Media on Tissue Transparency and Shrinkage

Analyzing Structural and Functional Testicular Anatomy

Fleck, Kenzler et al. have shown that, in mice, muscle-like cells are located within the walls of seminiferous tubules. Using CLARITY and a Leica digital light-sheet (DLS) microscope, Fleck, Kenzler…
Analyzing Structural and Functional Testicular Anatomy

Fish and Chips Sheet into the Light

The zebrafish larval brain is small and contains about 1 million times less neurons than the human counterpart. The neural circuitry and the general bauplan of the vertebrate brain, however, is…
Fish and Chips Sheet into the Light

Understanding Motor Sequence Generation Across Spatiotemporal Scales

We have developed a microscopy-based pipeline to characterize a developmentally critical behavior at the pupal stage of development, called the ecdysis sequence. We study brain-wide neuronal activity…
Understanding Motor Sequence Generation Across Spatiotemporal Scales

A Quality Metric for the Systematic Evaluation of Clearing Protocols

3D multicellular spheroids are of interest for studying tumor behavior and evaluating the response of pharmacologically active agents, because they mimic the in vivo tumor environment better than…
A Quality Metric for the Systematic Evaluation of Clearing Protocols

Campos de aplicação

Organoides e cultura celular 3D

Um dos recentes avanços mais impressionantes na pesquisa de ciências da vida é o desenvolvimento de sistemas de cultura celular 3D, como organoides, esferoides ou modelos órgão-em-chip. Uma cultura…

Organismos modelo na pesquisa

Um organismo modelo é uma espécie usada pelos pesquisadores para estudar processos biológicos específicos. Eles têm características genéticas similares aos seres humanos e são usados tipicamente em…

Imagens de células vivas

Alterando a perspectiva de componentes únicos de um microscópio a uma solução de imagens de células vivas completamente em funcionamento, a Leica Microsystems integra o microscópio, o software de…
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