Leica EM UC7 Ultramicrotomes & Cryo-Ultramicrotomes Sample Preparation for Electron Microscopy Products Home Leica Leica Microsystems
For Perfect Sectioning at Room Temperature and Cryo

Ultramicrotomo per il sezionamento perfetto a temperatura ambiente e criogenico Leica EM UC7

  • Micro- and nano-tubules built from loosely and tightly rolled up thin sheets†, Luisa Losensky,a Björn Goldenbogen,b Gudrun Holland,c Michael Laue,c Anca Petran,d Jürgen Liebscher,d Holger A. Scheidt,e Alexander Vogel,e Daniel Huster,e Edda Klippb and Anna Arbuzova*a, a Molecular Biophysics, Institute of Biology, Humboldt-Universität zu Berlin, Invalidenstr. 42, 10115 Berlin, Germany. E-mail: arbuzova(at) b Theoretical Biophysics, Institute of Biology, Humboldt-Universita¨t zu Berlin, Invalidenstr. 42, 10115 Berlin, Germany c Robert Koch Institute, ZBS 4, Seestr. 10, 13353 Berlin, Germany d National Institute of Research and Development for Isotopic and Molecular Technologies, Donat 67-103, RO-400293 Cluj-Napoca, Romania e Institute of Medical Physics and Biophysics, University of Leipzig, Härtelstr. 16–18, 04107 Leipzig, Germany † Electronic supplementary information (ESI) available: CholAU-d6 synthesis procedure, and additional light, electron and atomic force microscopy images. See DOI: 10.1039/c5cp06084b,

  • Features of the Antitumor Effect of Vaccinia Virus Lister Strain, Evgeniy Zonov1, Galina Kochneva2, Anastasiya Yunusova1, Antonina Grazhdantseva2, Vladimir Richter1 and Elena Ryabchikova1, 1 Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences (ICBFM SB RAS), 8 Lavrentiev Avenue, Novosibirsk 630090, Russia, 2 State Research Center of Virology and Biotechnology “Vector”, Koltsovo 630559, Russia, * Correspondence: Tel.: +7-383-363-51-63; Fax: +7-383-363-51-53,
  • PEDF and PEDF-derived peptide 44mer stimulate cardiac triglyceride degradation via ATGL,  Hao Zhang1,2†, Teng Sun2†, Xia Jiang2, Hongli Yu3, Meng Wang3, Tengteng Wei2, Huazhu Cui2, Wei Zhuang3, Zhiwei Liu3, Zhongming Zhang1,2* and Hongyan Dong3*, †Equal contributors, 1Department of Thoracic and Cardiovascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China, 2Department of Thoracic Cardiovascular Surgery, Affiliated Hospital of Xuzhou Medical College, Xuzhou 221006, China, 3Research Facility Center for Morphology, Xuzhou Medical College, Xuzhou 221004, China, Zhang et al. Journal of Translational Medicine (2015) 13:68
  • Aberrant DNA hypermethylation reduces the expression of the desmosome-related molecule periplakin in esophageal squamous cell carcinoma, Takeshi Otsubo1*, Teruki Hagiwara1*, Miwa Tamura-Nakano2, Takuhito Sezaki1, Oki Miyake3, Chihaya Hinohara3, Toshio Shimizu3, Kazuhiko Yamada3, Taeko Dohi1† & Yuki I. Kawamura1; 1Department of Gastroenterology, Research Center for Hepatitis and Immunology, Research Institute, National Center for Global Health and Medicine, 1-7-1 Kohnodai, Ichikawa, Chiba 272-8516, Japan, 2Communal Laboratory, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan, 3Department of Surgery, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan, Cancer Medicine 2015, 4(3):415–425

  • Morphology Control of Polymer Microspheres Containing Block Copolymers with Seed Polymerization, Hossein Taherzadeh, Shunsuke Sotowa, Kenji Ogino*,Graduate School of Bio-Applications and Systems Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo, Japan, Scientific Research Publishing Inc., Open Journal of Organic Polymer Materials, 2015, 5, 43-50

  • High levels of TopBP1 induce ATR-dependent shut-down of rRNA transcription and nucleolar Segregation, Miiko Sokka1,2,*, Kirsi Rilla2, Ilkka Miinalainen3, Helmut Pospiech4,5 and Juhani E. Syväoja2; 1Department of Biology, University of Eastern Finland, FI-80101 Joensuu, Finland, 2Institute of Biomedicine, University of Eastern Finland, FI-70211 Kuopio, Finland, 3Biocenter Oulu, University of Oulu, FI-90014 Oulu, Finland, 4Leibniz Institute for Age Research–Fritz Lipmann Institute, D-07745 Jena, Germany and 5Faculty of Biochemistry and Molecular Medicine, University of Oulu, FI-90014 Oulu, Finland, Oxford University Press, Nucleic Acids Research, 2015 1

  • Morphological study of Insoluble Organic Matter from carbonaceous chondrites: Correlation with petrologic grade, Hitesh G. Changela *, George Washington University, Department of Physics, 725 21st Street NW, Washington, DC 20052, USA, Naval Research Laboratory, 4555 Overlook Ave. SW, Washington, DC 20375, USA, Elsevier Ltd, Geochimica et Cosmochimica Acta, Volume 159, 15 June 2015, Pages 285–297

  • Spider's super-glue: thread anchors are composite adhesives with synergistic hierarchical organization†,  Jonas O. Wolff,*a, Ingo Grawe,ab, Marina Wirth,a , André Karstedt a and Stanislav N. Gorba; a Department of Functional Morphology and Biomechanics, University of Kiel, Am Botanischen Garten 1-9, D-24098 Kiel, Germany. bDepartment of Mechanical Engineering, Westphalian Institute for Biomimetics, University of Applied Sciences, Münsterstrasse 265, 46397 Bocholt, Germany, The Royal Society of Chemistry 2015,  Soft Matter, 2015, 11, 2394–2403

  • Insect-Specific Viruses Detected in Laboratory Mosquito Colonies and Their PotentialImplications for Experiments Evaluating Arbovirus Vector Competence, Bethany G. Bolling,* Nikos Vasilakis, Hilda Guzman, Steven G. Widen, Thomas G. Wood, Vsevolod L. Popov, Saravanan Thangamani, and Robert B. Tesh, Department of Pathology, University of Texas Medical Branch, Galveston, Texas, Am. J. Trop. Med. Hyg., 92(2), 2015, pp. 422–428
  • High-Performance and Moisture-Stable Cellulose−Starch Nanocomposites Based on Bioinspired Core−Shell Nanofibers, Kasinee Prakobna,†,‡ Sylvain Galland,†,‡ and Lars A. Berglund*,†,‡; †Department of Fibre and Polymer Technology and ‡Wallenberg Wood Science Centre, KTH Royal Institute of Technology, SE-10044 Stockholm, Sweden, ACS Publications, DOI: 10.1021/bm5018194

    Biomacromolecules 2015, 16, 904−912

  • Correlation of two-photon in vivo imaging and FIB/SEM microscopy, L. BLAZQUEZ-LLORCA∗, E. HUMMEL†, H. ZIMMERMAN†, C. ZOU∗, S. BURGOLD∗, J . RIETDORF† & J . HERMS∗, ‡, ∗Center for Neuropathology and Prion Research (ZNP) and German Center for Neurodegenerative Diseases (DZNE) – siteMunich, Ludwig-Maximilians-University Munich,Munich, Germany, †Carl ZeissMicroscopy,Munich, Germany, ‡Munich Cluster of Systems Neurology (SyNergy), Ludwig-Maximilians-University,Munich,Munich, Germany, Journal ofMicroscopy, Vol. 000, Issue 00 2015, pp. 1–8

  • Extended Ultrastructural Characterization of Chordoma Cells: The Link to New Therapeutic Options, Dagmar Kolb1,2, Elisabeth Pritz2, Bibiane Steinecker-Frohnwieser3, Birgit Lohberger4, Alexander Deutsch5, Thomas Kroneis2, Amin El-Heliebi2, Gottfried Dohr2, Katharina Meditz1, Karin Wagner1, Harald Koefeler1, Gerd Leitinger2, Andreas Leithner4, Bernadette Liegl-Atzwanger6, Dagmar Zweytick7, Beate Rinner1*; 1 Center for Medical Research, Medical University of Graz, Graz, Austria, 2 Institute of Cell Biology, Histology & Embryology, Medical University of Graz, Graz, Austria, 3 Ludwig Boltzmann Institute for Rehabilitation of Internal Diseases, Ludwig Boltzmann Cluster for Rheumatology, Balneology and Rehabilitation, Saalfelden, Austria, 4 Department of Orthopaedic Surgery, Medical University of Graz, Graz, Austria, 5 Division of Hematology, Department of Internal Medicine, Medical University of Graz, Graz, Austria, 6 Institute of Pathology, Medical University of Graz, Graz, Austria, 7 Biophysics Division, Institute of Molecular Biosciences, University of Graz, Graz, Austria; PLOS ONE | DOI:10.1371/journal.pone.0114251;
  • Intracellular accumulation and immunological properties of fluorescent gold nanoclusters in human dendritic cells, Tahia D. Fern_andez a, 1, John R. Pearson b, Manuel Pernia Leal c, Maria J. Torres a, d, Miguel Blanca a, d, Cristobalina Mayorga a, d, 1, Xavier Le Gu_evel e, *; a Research Laboratory and Allergy Service, IBIMA, Regional University M_alaga Hospital, UMA, M_alaga, Spain; b The Andalusian Centre for Nanomedicine and Biotechnology (BIONAND) Nano-imaging Unit (Junta de Andalucía-Universidad de Malaga), M_alaga, Spain; c Diagnostic Area, The Andalusian Centre for Nanomedicine and Biotechnology, BIONAND (Junta de Andalucia-Universidad de Malaga), M_alaga, Spain; d Allergy Service, Carlos Haya Hospital, M_alaga, Spain; e Therapeutic Nanosystems, The Andalusian Centre for Nanomedicine and Biotechnology, BIONAND, M_alaga, Spain; 2014 Elsevier Ltd;
  • Hydrogen sulfide is essential for Schwann cell responses to peripheral nerve injury, Byung Sun Park1, Hyun-Wook Kim2, Im Joo Rhyu2, Chan Park1, Seung Geun Yeo3, Youngbuhm Huh1, Na Young Jeong4,* and Junyang Jung1,*; 1 Department of Anatomy and Neurobiology, School of Medicine, Biomedical Science Institution, Kyung Hee University, Seoul, Korea; 2 Department of Anatomy, College of Medicine, Korea University, Seoul, Korea; 3 Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, Seoul, Korea; 4 Department of Anatomy and Cell Biology, College of Medicine, Dong-A University, Busan, Korea; *Address correspondence and reprint requests to Junyang Jung, Department of Anatomy and Neurobiology, School of Medicine, Kyung Hee University, Seoul 130-701, Korea;  2014 International Society for Neurochemistry, DOI: 10.1111/jnc.12932;;jsessionid=0827DFEB81035C36548B27083234CEE5.f01t03?deniedAccessCustomisedMessage=&userIsAuthenticated=false
  • STEM-in-SEM high resolution imaging of gold nanoparticles and bivalve tissues in bioaccumulation experiments†, C. A. García-Negrete,*a M. C. Jiménez de Haro,a J. Blasco,b M. Sotoc and A. Fernández*a; a Instituto de Ciencia de Materiales de Sevilla (CSIC - Univ. Sevilla), Avda. Américo Vespucio nr. 49, CIC Cartuja, 41092 Sevilla, Spain; bInstituto de Ciencias Marinas de Andalucía (ICMAN-CSIC), Campus Universitario Río San Pedro, 11519 Puerto Real (Cádiz), Spain; cZoology and Cell Biology Dept., Science and Technology Faculty & Research Centre in Experimental Marine Biology and Biotechnology (PiE-UPV/EHU) University of the Basque Country, Sarriena auzoa Z/G, 48940 Leioa-Bizkaia, Basque Country, Spain; The Royal Society of Chemistry 2015, DOI: 10.1039/c4an01643b;
  • Significant correlation between refractive index and activity of mitochondria: single mitochondrion study, Keisuke Haseda,1 Keita Kanematsu,1 Keiichi Noguchi,2 Hiromu Saito,3 Norihiro Umeda,4 and Yoshihiro Ohta1,*; 1Division of Biotechnology and Life Sciences, Institute of Engineering, Tokyo University of Agriculture and Technology, Nakacho 2-24-16, Koganei, Tokyo 184-8588, Japan; 2Instrumentation Analysis Center, Tokyo University of Agriculture and Technology, Nakacho 2-24-16, Koganei, Tokyo 184-8588, Japan; 3Division of Organic and Polymer Materials Chemistry, Tokyo University of Agriculture and Technology, 2-24-16 Nakacho, Koganei, Tokyo 184-8588, Japan; 4Division of Mechanical Systems Engineering, Institute of Engineering, Tokyo University of Agriculture and Technology, Nakacho 2-24-16, Koganei, Tokyo 184-8588, Japan; 2015 Optical Society of America, DOI:10.1364/BOE.6.000859,
  • Long-term follow-up of post hematopoietic stem cell transplantation for Hurler syndrome: Clinical, biochemical, and pathological improvements, Eriko Yasuda a,b,1,William G. Mackenzie a,1, Kristen D. Ruhnke a, Tsutomu Shimada a, Robert W. Masona, Jozef Zustin d, Paul L.Martine, Mihir M. Thacker a, Tadao Orii c, Yoshimichi Sai b, Shunji Tomatsu a,c,1,*; a Nemours/Alfred I. duPont Hospital for Children, Wilmington, DE, United States; b Department of Medical Informatics, Graduate School of Medical Sciences, Kanazawa University, Japan; c Department of Pediatrics, Gifu University, Gifu, Japan; d Institute of Pathology, University Medical Center Muenster, Germany; e Division of Pediatric Blood and Marrow Transplant, Children's Health Center, Duke University Medical Center, United States; Elsevier Inc,
  • Cell type dependent changes in CdSe/ZnS quantum dot uptake and toxic endpoints,  Bella B. Manshian, †‡ Stefaan J. Soenen, ‡ Abdullah Al-Ali, † Andy Brown, § Nicole Hondow, § John Wills,† Gareth J.S. Jenkins,† Shareen H. Doak.*; †Institute of Life Science, College of Medicine, Swansea University, Singleton Park, Swansea SA2 8PP, UK; ‡Biomedical NMR unit-MoSAIC, Department of Medicine, KU Leuven, B-3000 Leuven, Belgium; §Institute for Materials Research, SCaPE, University of Leeds, Leeds LS2 9JT, UK; ToxSci Advance Access published January 19, 2015;
  • Synthesis and electrical properties of In2O3(ZnO) superlattice nanobelt*, Tang Xin-Yue(唐欣月)a), Gao Hong(高红)a)†, Wu Li-Li(武立立)b), Wen Jing(温静)a), Pan Si-Ming(潘思明)a), Liu Xin(刘欣)a), and Zhang Xi-Tian(张喜田)a)‡; a)Key Laboratory for Photonic and Electronic Bandgap Materials, Ministry of Education, School of Physics and Electronic Engineering, Harbin Normal University, Harbin 150025, China; b)Center for Engineering Training and Basic Experimentation, Heilongjiang University of Science and Technology, Harbin 150022, China; 2015 Chinese Physical Society and IOP Publishing Ltd, DOI: 10.1088/1674-1056/24/2/027305;
  • Imaging the Drosophila retina: zwitterionic buffers PIPES and HEPES induce morphological artifacts in tissue fixation, Jing Nie1,2, Simpla Mahato1 and Andrew C Zelhof1*; 1Department of Biology, Indiana University, 1001 East Third St, Bloomington, IN 47405, USA; 2015 Nie et al.; licensee BioMed Central, DOI 10.1186/s12861-015-0056-y;