Détecter les détails dissimulés
Outil de photomanipulation multispectrale Infinity Scanner

Imagerie des cellules vivantes
Passant de la perspective basée sur des composants de microscopes individuels à la solution d'imagerie des cellules vivantes parfaitement fonctionnelle, Leica Microsystems intègre le microscope, le…
Read article
![Photomanipulation [Translate to french:] Leica photomanipulation](https://webcdn.leica-microsystems.com/fileadmin/_processed_/3/8/csm_photomanipulation-res_8c946c07f1.jpg)
Photomanipulation
Le terme de photomanipulation se réfère à une série de techniques qui utilisent les propriétés des molécules fluorescentes pour déclencher des événements et observer comment les ensembles dynamiques…
Read article

Science Lab Topic:
Fluorescence Microscopy
What is Photomanipulation?
The term photomanipulation describes a wide range of techniques that enable the microscopist the transition from passive observer to instigator of events by offering a way of interacting with their…
Read article

Science Lab Topic:
Fluorescence Microscopy
Photoactivatable, photoconvertible, and photoswitchable Fluorescent Proteins
Fluorescent proteins (FPs) such as GFP, YFP or DsRed are powerful tools to visualize cellular components in living cells. Nevertheless, there are circumstances when classical FPs reach their limits.…
Read article

Science Lab Topic:
Neuroscience
Clap On, Clap Off. Protein On, Protein Off
Unlike genetic or pharmacological manipulation, light-controlled proteins respond immediately, can be temporally and spatially triggered, are reversible, and are specific to the protein of interest.…
Read article

Science Lab Topic:
Neuroscience
Video Talk by Karl Deisseroth: Optogenetics
Optogenetics is a combination of genetics and optics to achieve a gain or loss of function of biochemical events such as action potentials in a particular neuron or tissue. Opsin genes encode proteins…
Read article

Science Lab Topic:
Neuroscience
Optogenetic Toolkit Goes Multicolor
Optogenetics is a technique that allows scientists to control neurons’ electrical activity with light by engineering them to express light-sensitive proteins. Within the past decade, it has become a…
Read article

Science Lab Topic:
Neuroscience
Optogenetics
Optogenetics is a technique that allows light-controlled responses of transfected cells. The cells are genetically modified by introduction of genes that code for light-induced channels or ion pumps.…
Read article

Science Lab Topic:
Confocal Microscopy
Live-cell Imaging Techniques
The understanding of complex and/or fast cellular dynamics is an important step for exploring biological processes. Therefore, today’s life science research is increasingly focusing on dynamic…
Read article

Science Lab Topic:
Confocal Microscopy
Fluorescence Recovery after Photobleaching (FRAP) and its Offspring
FRAP (Fluorescence recovery after photobleaching) can be used to study cellular protein dynamics: For visualization the protein of interest is fused to a fluorescent protein or a fluorescent dye. A…
Read article