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AI-Powered Hi-Plex Spatial Analysis Tools for Breast Cancer Research
Breast cancer (BC) is the leading cause of cancer-related deaths in women. Investigating the tumor microenvironment (TME) is crucial to elucidate the mechanisms of tumor progression. Systematic…
Focus on Long-Term Imaging in 3D with Light Sheet Microscopy
Long-term 3D imaging reveals how complex multicellular systems grow and develop and how cells move and interact over time, unlocking critical insights into development, disease, and regeneration.…
How AR Fluorescence Imaging Supports Neurovascular Surgery
In this article, we explain how fluorescence imaging works in vascular neurosurgery and explain the benefits of the GLOW800 Augmented Reality fluorescence application.
Ultramicrotome Sectioning of Polymers for TEM Analysis
We demonstrate the capabilities of the UC Enuity ultramicrotome from Leica Microsystems for preparing ultrathin sections of polymer samples under both ambient and cryogenic conditions. By presenting…
Polarizing Microscope Image Gallery
How polarization microscope images can be used for analysis is shown in this gallery. Polarized light microscopy (also known as polarizing microscopy) is an important method for different fields and…
Biomarker Discovery with Laser Microdissection
Explore the potential of spatial proteomics workflows, such as Deep Visual Proteomics (DVP), to decipher pathology mechanisms and uncover druggable targets.
Altered protein expression, abundance, or…
Faster & Deeper Insights into Organoid and Spheroid Models
Gain deeper, more translatable, insights into organoid and spheroid models for drug discovery and disease research by overcoming key imaging challenges. In this eBook, explore advanced microscopy…
Volume EM and AI Image Analysis
The article outlines a detailed workflow for studying biological tissues in three dimensions using volume-scanning electron microscopy (volume-SEM) combined with AI-assisted image analysis. The focus…
A Guide to C. elegans Research – Working with Nematodes
Efficient microscopy techniques for C. elegans research are outlined in this guide. As a widely used model organism with about 70% gene homology to humans, the nematode Caenorhabditis elegans (also…
How a Breakthrough in Spatial Proteomics Saved Lives
Toxic epidermal necrolysis (TEN) is a rare but devastating reaction to common medications like antibiotics or gout treatments. It begins innocuously, often as a rash, but can escalate rapidly into…
