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Découvrez de nouvelles applications en combinant microscopie confocale et à feuille de lumière

Microscope Digital Light Sheet STELLARIS DLS

  • Organoïdes et culture cellulaire en 3D

    L’une des avancées récentes les plus passionnantes de la recherche en sciences de la vie est le développement de systèmes de culture cellulaire en 3D, tels que les organoïdes, les sphéroïdes ou les…
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  • Organismes modèles dans la recherche

    Un organisme modèle désigne une espèce utilisée par les chercheurs pour étudier des processus biologiques spécifiques. Ils présentent des caractéristiques génétiques similaires à celles de l’homme et…
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    Imagerie des cellules vivantes

    Passant de la perspective basée sur des composants de microscopes individuels à la solution d'imagerie des cellules vivantes parfaitement fonctionnelle, Leica Microsystems intègre le microscope, le…
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  • Science Lab Topic: Light Sheet Microscopy

    Effects of Clearing Media on Tissue Transparency and Shrinkage

    This study comprehensively evaluates the effects of different clearing media on tissue transparency and shrinkage by comparing freshly dissected dipteran fly brains with their cleared equivalents.…
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  • Science Lab Topic: Light Sheet Microscopy

    Following Ca²⁺ Changes in Acutely Stimulated Spheroids

    Spheroids are easy and cost-effective 3D cell cultures, useful for fundamental and applied research. They can bridge the gap between 2D and in vivo experiments and can be used for high-throughput…
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  • Science Lab Topic: Light Sheet Microscopy

    Analyzing Structural and Functional Testicular Anatomy

    Fleck, Kenzler et al. have shown that, in mice, muscle-like cells are located within the walls of seminiferous tubules. Using CLARITY and a Leica digital light-sheet (DLS) microscope, Fleck, Kenzler…
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  • Science Lab Topic: Light Sheet Microscopy

    Fish and Chips Sheet into the Light

    The zebrafish larval brain is small and contains about 1 million times less neurons than the human counterpart. The neural circuitry and the general bauplan of the vertebrate brain, however, is…
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  • Science Lab Topic: Light Sheet Microscopy

    Understanding Motor Sequence Generation Across Spatiotemporal Scales

    We have developed a microscopy-based pipeline to characterize a developmentally critical behavior at the pupal stage of development, called the ecdysis sequence. We study brain-wide neuronal activity…
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  • Science Lab Topic: Light Sheet Microscopy

    A Quality Metric for the Systematic Evaluation of Clearing Protocols

    3D multicellular spheroids are of interest for studying tumor behavior and evaluating the response of pharmacologically active agents, because they mimic the in vivo tumor environment better than…
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