Leica TCS SP5 II Confocal Microscopes Leica Leica Microsystems

Leica TCS SP5 II

Publications using Leica TCS SP5 microscopes

  • ZAP-70 enhances migration of malignant B lymphocytes towards CCL21 by inducing CCR7 expression via IgM-ERK1/2 activation.
    Blood 2011 blood-2011-01-333682.Published online before print August 24, 2011. Calpe, et al.
  • Peptidylarginine deiminase type 2 is over expressed in the glaucomatous optic nerve. Mol Vis. 2010 Aug 17;16:1654-8. Cafaro TA, Santo S, Robles LA, Crim N, Urrets-Zavalia JA, Serra HM. CIBICI, Faculty of Chemistry, National University of Córdoba, Argentina. http://www.ncbi.nlm.nih.gov/pubmed/20806090
  • Defective Ca2+ channel clustering in axon terminals disturbs excitability in motoneurons in spinal muscular atrophy.
    J Cell Biol. 2007 Oct 8;179(1):139-49. Jablonka S, Beck M, Lechner BD, Mayer C, Sendtner M. Institute for Clinical Neurobiology, University of Wuerzburg, Wuerzburg D-97078, Germany. http://www.ncbi.nlm.nih.gov/pubmed/17923533

Publications using Leica TCS SP5 AOBS microscopes

  • Liposome-delivered ATP effectively protects the retina against ischemia-reperfusion injury. Mol Vis. 2010 Dec 28;16:2882-90. Dvoriantchikova G1, Barakat DJ2, Hernandez E1, Shestopalov VI1,2, Ivanov D1,3. 1Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, FL; 2Department of Cell Biology and Anatomy, University of Miami Miller School of Medicine, Miami, FL; 3Vavilov Institute of General Genetics RAS, Moscow, Russian Federation. http://www.ncbi.nlm.nih.gov/pubmed/21203410
  • Toll-like receptor 4 contributes to retinal ischemia/reperfusion injury.
    Molecular Vision 2010; 16:1907-1912. Dvoriantchikova G1, Barakat DJ2, Hernandez E1, Shestopalov VI1,2, Ivanov D1,3. 1Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, FL; 2Department of Cell Biology and Anatomy, University of Miami Miller School of Medicine, Miami, FL; 3Vavilov Institute of General Genetics RAS, Moscow, Russian Federation. http://www.molvis.org/molvis/v16/a207/
  • EGF-induced MAPK Signaling Inhibits Hemidesmosome Formation through Phosphorylation of the Integrin β4. J. Biol. Chem. 2010 285: 37650-37662. Evelyne Frijns, Norman Sachs, Maaike Kreft, Kevin Wilhelmsen and Arnoud Sonnenberg. Division of Cell Biology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
  • Facilitated and Site-Specific Assembly of Functional Polystyrene Microspheres on Patterned Porous Films. ACS Appl. Mater. Interfaces; 2010, 2 (12):3759–3765. Ling-Shu Wan, Jie Lv, Bei-Bei Ke, and Zhi-Kang Xu. MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China. http://pubs.acs.org/doi/abs/10.1021/am1009277
  • Central and peripheral neuronal pathways revealed by backfilling with neurobiotin in the optic, tentacular and small labial nerves of Lymnaea stagnalis. Acta Zoologica. First published online: 19 Oct 2010. Tuchina, O. P., Zhukov, V. V. and Meyer-Rochow, V. B. http://onlinelibrary.wiley.com/doi/10.1111/j.1463-6395.2010.00477.x/full
  • Liposome-delivered ATP effectively protects the retina against ischemia-reperfusion injury. Mol Vis. 2010 Dec 28;16:2882-90. Dvoriantchikova G1, Barakat DJ2, Hernandez E1, Shestopalov VI1,2, Ivanov D1,3. 1Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, FL; 2Department of Cell Biology and Anatomy, University of Miami Miller School of Medicine, Miami, FL; 3Vavilov Institute of General Genetics RAS, Moscow, Russian Federation. http://www.ncbi.nlm.nih.gov/pubmed/21203410
  • Visualisation and Quantification of Intracellular Interactions of Neisseria meningitidis and Human α-actinin by Confocal Imaging. JoVE. 44; 2010. Isabel Murillo, Mumtaz Virji. Department of Cellular and Molecular Medicine, University of Bristol, UK. https://www.jove.com/details.stp?id=2045
  • Rab27a Is Required for Human Cytomegalovirus Assembly. PloS ONE. 2010 Dec 8. Alberto Fraile-Ramos1, Victoria Cepeda1, Edo Elstak2, Peter van der Sluijs2. 1 Department of Molecular and Cell Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, Madrid, Spain, 2 Department of Cell Biology, University Medical Center Utrecht, Utrecht, The Netherlands. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0015318#s2
  • Microenvironmental Regulation of Glioblastoma Radioresponse. Clin Cancer Res December 15, 2010 16:6049-6059; Published OnlineFirst October 29, 2010. Muhammad Jamal1, Barbara H. Rath1, Eli S. Williams1, Kevin Camphausen2, and Philip J. Tofilon1.  1Drug Discovery Department, Moffitt Cancer Center, Tampa, Florida; and 2Radiation Oncology Branch, National Cancer Institute, Bethesda, Maryland. http://clincancerres.aacrjournals.org/content/16/24/6049.abstract
  • Focal Ca2+ Transient Detection in Smooth Muscle. JoVE. 28; 2009
    John S. Young, Robert J. Amos, Keith L. Brain. Department of Pharmacology, University of Oxford. https://www.jove.com/Details.stp?ID=1247
  • Potential for Raman spectroscopy to provide cancer screening using a peripheral blood sample. Head Neck Oncol. 2009 Sep 17;1:34. Harris AT, Lungari A, Needham CJ, Smith SL, Lones MA, Fisher SE, Yang XB, Cooper N, Kirkham J, Smith DA, Martin-Hirsch DP, High AS. Oral Biology, Leeds Dental Institute, University of Leeds, Leeds, UK. andrew.harris@doctors.org.uk http://www.ncbi.nlm.nih.gov/pubmed/19761601
  • Novel interactions of CLN5 support molecular networking between Neuronal Ceroid Lipofuscinosis proteins. BMC Cell Biology 2009, 10:83
    Annina Lyly, Carina von Schantz, Claudia Heine, Mia-Lisa Schmiedt, Tessa Sipilä, Anu Jalanko and Aija Kyttälä. http://www.springerlink.com/content/l2pk506j32674201/
  • Live imaging of mammalian retina: rod outer segments are stained by conventional mitochondrial dyes. J Biomed Opt. 2008 Sep-Oct;13(5):054017. Bianchini P, Calzia D, Ravera S, Candiano G, Bachi A, Morelli A, Bruschi M, Pepe IM, Diaspro A, Panfoli I. University of Genoa, Laboratory for Advanced, Microscopy, Bioimaging, and Spectroscopy (LAMBS), MicroSCoBiO Research Center, Department of Physics, Via Dodecaneso 33, 16146, Genoa, Italy. http://www.ncbi.nlm.nih.gov/pubmed/19021397
  • Plasmon resonance coupling of metal nanoparticles for molecular imaging of carcinogenesis in vivo. J Biomed Opt. 2007 May-Jun;12(3):034007. Aaron J, Nitin N, Travis K, Kumar S, Collier T, Park SY, José-Yacamán M, Coghlan L, Follen M, Richards-Kortum R, Sokolov K. University of Texas at Austin, Department of Biomedical Engineering, Austin, Texas 78712, USA. http://www.ncbi.nlm.nih.gov/pubmed/17614715
  • Unloading kinesin transported cargoes from the tubulin track via the inflammatory c-Jun N-terminal kinase pathway. FASEB J. 2006 Dec;20(14):2573-5. Epub 2006 Oct 26. Stagi M, Gorlovoy P, Larionov S, Takahashi K, Neumann H. Neural Regeneration Unit, Institute of Reconstructive Neurobiology, University Bonn Life and Brain Center, University Bonn, Germany. http://www.ncbi.nlm.nih.gov/pubmed/17068110

Publications using Leica TCS SP2  microscopes

  • Intrarenal Renin Angiotensin System Revisited: Role Of Megalin-dependent Endocytosis Along The Proximal Nephron. Biol. Chem. 2010 285: 41935-41946. First Published on October 21, 2010. Marcus Pohl1, Henriette Kaminski1, Hayo Castrop2, Michael Bader3, Nina Himmerkus‖, Markus Bleich4, Sebastian Bachmann1 and Franziska Theilig1. 1Institute of Anatomy, Charité Universitätsmedizin, 10115 Berlin, Germany, 2Institute of Physiology, University Regensburg, 93053 Regensburg, Germany, 3Max-Delbrück-Center for Molecular Medicine, 13092 Berlin, Germany, and  4Institute of Physiology, 24118 Kiel, Germany. http://www.jbc.org/content/285/53/41935.abstract
  • Hydrogen protects vestibular hair cells from free radicals. Acta Oto-Laryngologica. 2010; 130: 95–100. Akiko Taura1, Yayoi S Kikkawa2, Takyuki Nakagawa1 & Juichi Ito1. 1Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto and 2Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan. http://www.sciencenet.cn/upload/blog/file/2010/12/20101222192453754498..pdf
  • Endocytic trafficking of Rac is required for the spatial restriction of signaling in cell migration. Cell. 2008 Jul 11;134(1):135-47.Palamidessi A, Frittoli E, Garré M, Faretta M, Mione M, Testa I, Diaspro A, Lanzetti L, Scita G, Di Fiore PP.IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20139 Milan, Italy. http://www.ncbi.nlm.nih.gov/pubmed/18614017
  • Functionally unequal centrosomes drive spindle orientation in asymmetrically dividing Drosophila neural stem cells. Dev Cell. 2007 Mar;12(3):467-74. Rebollo E, Sampaio P, Januschke J, Llamazares S, Varmark H, González C. Cell Division Group, Institute for Research in Biomedicine, Parc Científic Barcelona, C/ Josep Samitier 1-5, 08028 Barcelona, Spain. http://www.ncbi.nlm.nih.gov/pubmed/17336911
  • Involvement of the actin cytoskeleton and homotypic membrane fusion in ER dynamics in Caenorhabditis elegans. Mol Biol Cell. 2005 May; 16(5):2139-53. Epub 2005 Feb 16. Poteryaev D, Squirrell JM, Campell JM, White JG, Spang A. Friedrich Miescher Laboratorium, Max Planck Gesellschaft, D-72076 Tübingen, Germany. http://www.ncbi.nlm.nih.gov/pubmed/15716356

Publications using Leica TCS SP2 AOBS microscopes

  • Tissue Factor Regulates Microvessel Formation and Stabilization by Induction of Chemokine (C-C motif) Ligand 2 Expression. Arterioscler Thromb Vasc Biol. 2011;31:2607-2615, published online before print August 25 2011. Gemma Arderiu, Esther Peña, Rosa Aledo, Oriol Juan-BabotLina Badimon http://atvb.ahajournals.org/content/suppl/2011/08/25/ATVBAHA.111.233536.DC1/Arderiu_et_al._Supplemental_Material._ATVB2011233536-1.pdf
  • Profilin II Regulates the Exocytosis of Kainate Glutamate Receptors. J. Biol. Chem. 2010 285: 40060-40071. First Published on October 11, 2010. Magali Mondin, Mario Carta, Elisabeth Normand, Christophe Mulle, Françoise Coussen. Laboratoire Physiologie Cellulaire de la Synapse, CNRS UMR 5091, University of Bordeaux, 146 rue Léo Saignat, 33077 Bordeaux, France. http://www.jbc.org/content/285/51/40060.abstract
  • The Plk1 Inhibitor BI 2536 Temporarily Arrests Primary Cardiac Fibroblasts in Mitosis and Generates Aneuploidy In Vitro. PloS ONE. 2010 Sep 24.1Bo Lu, Hasan Mahmud, 1Alexander H. Maass, 2Bo Yu, 1Wiek H. van Gilst, 1Rudolf A. de Boer, 1Herman H. W. Silljé. 1Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, 2Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Key Laboratories of Education Ministry for Myocardial Ischemia Mechanism and Treatment, Harbin, China. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0012963#abstract0
  • Overexpression of E-cadherin on melanoma cells inhibits chemokine-promoted invasion involving p190RhoGAP/p120ctn-dependent inactivation of RhoA. J Biol Chem. 2009 May 29;284(22):15147-57. Epub 2009 Mar 17. Molina-Ortiz I, Bartolomé RA, Hernández-Varas P, Colo GP, Teixidó J. Department of Cellular and Molecular Physiopathology, Centro de Investigaciones Biológicas, 28040 Madrid, Spain. http://www.ncbi.nlm.nih.gov/pubmed/19293150
  • Abnormal autophagy, ubiquitination, inflammation and apoptosis are dependent upon lysosomal storage and are useful biomarkers of mucopolysaccharidosis VI. Pathogenetics. 2009 Jun 16;2(1):4. Tessitore A, Pirozzi M, Auricchio A. Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy. http://www.ncbi.nlm.nih.gov/pubmed/19531206
  • MT1-MMP proinvasive activity is regulated by a novel Rab8-dependent exocytic pathway. EMBO J. 2007 Mar 21;26(6):1499-510. Epub 2007 Mar 1. Bravo-Cordero JJ, Marrero-Diaz R, Megías D, Genís L, García-Grande A, García MA, Arroyo AG, Montoya MC. Confocal Microscopy and Cytometry Unit, Biotechnology Programme, Spanish Nacional Cancer Research Center (CNIO), Madrid, Spain. http://www.jbc.org/content/285/51/40060.abstract
  • High-content microscopy identifies new neurite outgrowth regulators. Mol Biol Cell. 2007 Jan;18(1):242-52. Epub 2006 Nov 8. Laketa V, Simpson JC, Bechtel S, Wiemann S, Pepperkok R. Cell Biology and Biophysics Unit, European Molecular Biology Laboratory-Heidelberg, 69117 Heidelberg, Germany. http://www.ncbi.nlm.nih.gov/pubmed/17093056
  • NMSU’s Core University Research Resources Laboratory Supports Regional Collaborative Research and Exploration. NMSU RESEARCH NEWS, Newsletter of the Office of the Vice President for Research. Vol. 3,11.  Rad, Hamid M. NMSU’s Core University Research Resources Laboratory, New Mexico State University, Las Cruces, N.M. http://research.nmsu.edu/nl/ovpr_newsletter_v3_n11.pdf

Publications using Leica TCS SP2 RS microscopes


  • Properties of basal dendrites of layer 5 pyramidal neurons: a direct patch-clamp recording study. Nature Neuroscience 10, 206 - 214 (2007). Thomas Nevian1,2,4, Matthew E Larkum1,4, Alon Polsky3 & Jackie Schiller3. 1Department of Physiology, University of Berne, Bühlplatz 5, 3012 Berne, Switzerland. 2Department of Cell Physiology, Max Planck Institute for Medical Research, Jahnstrasse 29, 69120 Heidelberg, Germany. 3Department of Physiology, Technion Medical School, Bat-Galim, Haifa 31096, Israel. 4These authors contributed equally to this work. http://www.nature.com/neuro/journal/v10/n2/abs/nn1826.html
  • Spine Ca2+ signaling in spike-timing-dependent plasticity. J Neurosci. 2006 Oct 25;26(43):11001-13. Nevian T, Sakmann B. Department of Cell Physiology, Max-Planck Institute for Medical Research, D-69120 Heidelberg, Germany. http://www.ncbi.nlm.nih.gov/pubmed/17065442
  • MRT letter: high speed scanning has the potential to increase fluorescence yield and to reduce photobleaching. Microsc Res Tech. 2006 Sep;69(9):689-92. Borlinghaus RT. Leica Microsystems CMS, Am Friedensplatz 3, 68165 Mannheim, Germany. Rolf.Borlinghaus(at)Leica-microsystems(dot)comhttp://www.ncbi.nlm.nih.gov/pubmed/16878313
  • Cutting edge: Membrane nanotubes connect immune cells.
    J Immunol. 2004 Aug 1;173(3):1511-3. Onfelt B, Nedvetzki S, Yanagi K, Davis DM. Department of Biological Sciences, Imperial College, London, United Kingdom. http://www.ncbi.nlm.nih.gov/pubmed/15265877
  • No role for a voltage sensitive release mechanism in cardiac muscle.
    J Mol Cell Cardiol. 2003 Feb;35(2):145-51. Trafford AW, Eisner DA.

Publications using Leica TCS Multiphoton microscopes

  • Synaptic integration in tuft dendrites of layer 5 pyramidal neurons: a new unifying principle. Science. 2009 Aug 7; 325(5941):756-60. Larkum ME, Nevian T, Sandler M, Polsky A, Schiller J. Department of Physiology, University of Berne, Buehlplatz 5, 3012 Berne, Switzerland. http://www.ncbi.nlm.nih.gov/pubmed/19661433
  • Multi-photon excitation microscopy. Biomed Eng Online. 2006 Jun 6;5:36. Diaspro A, Bianchini P, Vicidomini G, Faretta M, Ramoino P, Usai C.
    LAMBS-MicroScoBio Research Center, Department of Physics, University of Genoa, Via Dodecaneso 33, 16146 Genova, Italy. http://www.ncbi.nlm.nih.gov/pubmed/16756664
  • Anthrax toxin receptor 2 mediates Bacillus anthracis killing of macrophages following spore challenge. Cell Microbiol. 2005 Aug;7(8):1173-85. Banks DJ, Barnajian M, Maldonado-Arocho FJ, Sanchez AM, Bradley KA. Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, USA. http://www.ncbi.nlm.nih.gov/pubmed/16008584