STELLARIS STED & STELLARIS 8 STED 共焦点顕微鏡 製品紹介 Home Leica Leica Microsystems

より速く真実にたどり着く

STED 顕微鏡 STELLARIS STED & STELLARIS 8 STED

Caveolae-mediated Tie2 signaling contributes to CCM pathogenesis in a brain endothelial cell-specific Pdcd10-deficient mouse model
Zhou HJ, Qin L, Jiang Q, Murray KN, Zhang H, Li B, Lin Q, Graham M, Liu X, Grutzendler J, Min W.
Nat Commun, 2021
10.1038/s41467-020-20774-0

The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein
Lu S, Ye Q, Singh D, Cao Y, Diedrich JK, Yates JR 3rd, Villa E, Cleveland DW, Corbett KD.
Nat Commun, 2021
10.1038/s41467-020-20768-y

Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin
Bacolla A, Sengupta S, Ye Z, Yang C, Mitra J, De-Paula RB, Hegde ML, Ahmed Z, Mort M, Cooper DN, Mitra S, Tainer JA.
Nucleic Acids Res, 2021
10.1093/nar/gkaa1120

Drosophila female germline stem cells undergo mitosis without nuclear breakdown
Duan T, Cupp R, Geyer PK.
Curr Biol, 2021
10.1016/j.cub.2021.01.033

High-resolution imaging reveals compartmentalization of mitochondrial protein synthesis in cultured human cells
Zorkau M, Albus CA, Berlinguer-Palmini R, Chrzanowska-Lightowlers ZMA, Lightowlers RN.
PNAS, 2021
10.1073/pnas.2008778118

LGI1-ADAM22-MAGUK configures transsynaptic nanoalignment for synaptic transmission and epilepsy prevention
Fukata Y, Chen X, Chiken S, Hirano Y, Yamagata A, Inahashi H, Sanbo M, Sano H, Goto T, Hirabayashi M, Kornau HC, Prüss H, Nambu A, Fukai S, Nicoll RA, Fukata M.
PNAS, 2021
10.1073/pnas.2022580118

Centriole and PCM cooperatively recruit CEP192 to spindle poles to promote bipolar spindle assembly
Chinen T, Yamazaki K, Hashimoto K, Fujii K, Watanabe K, Takeda Y, Yamamoto S, Nozaki Y, Tsuchiya Y, Takao D, Kitagawa D.
J Cell Biol, 2021
10.1083/jcb.202006085

Superresolution characterization of core centriole architecture
Tian Y, Wei C, He J, Yan Y, Pang N, Fang X, Liang X, Fu J.
J Cell Biol, 2021
10.1083/jcb.202005103

NIX initiates mitochondrial fragmentation via DRP1 to drive epidermal differentiation
Simpson CL, Tokito MK, Uppala R, Sarkar MK, Gudjonsson JE, Holzbaur ELF.
Cell Rep, 2021
10.1016/j.celrep.2021.108689

The FUS gene is dual-coding with both proteins contributing to FUS-mediated toxicity
Brunet MA, Jacques JF, Nassari S, Tyzack GE, McGoldrick P, Zinman L, Jean S, Robertson J, Patani R, Roucou X.
EMBO Rep, 2020
10.15252/embr.202050640

Stochastic asymmetric repartition of lytic machinery in dividing CD8(+) T cells generates heterogeneous killing behavior
Lafouresse F, Jugele R, Müller S, Doineau M, Duplan-Eche V, Espinosa E, Puisségur MP, Gadat S, Valitutti S.
Elife, 2021
10.7554/eLife.62691

TRIM37 prevents formation of centriolar protein assemblies by regulating Centrobin
Balestra FR, Domínguez-Calvo A, Wolf B, Busso C, Buff A, Averink T, Lipsanen-Nyman M, Huertas P, Ríos RM, Gönczy P.
Elife, 2021
10.7554/eLife.62640

Cabozantinib Unlocks Efficient In Vivo Targeted Delivery of Neutrophil-Loaded Nanoparticles into Murine Prostate Tumors
Chaudagar KK, Landon-Brace N, Solanki A, Hieromnimon HM, Hegermiller E, Li W, Shao Y, Joseph J, Wilkins DJ, Bynoe KM, Li XL, Clohessy JG, Ullas S, Karp JM, Patnaik A.
Mol Cancer Ther, 2021
10.1158/1535-7163.MCT-20-0167

Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds
Kowalczyk I, Lee C, Schuster E, Hoeren J, Trivigno V, Riedel L, Görne J, Wallingford JB, Hammes A, Feistel K.
Development, 2021
10.1242/dev.195008

The nuclear lamina is a hub for the nuclear function of Jacob
Samer S, Raman R, Laube G, Kreutz MR, Karpova A.
Mol Brain, 2021
10.1186/s13041-020-00722-1

SLX4IP Promotes Telomere Maintenance in Androgen Receptor-Independent Castration-Resistant Prostate Cancer through ALT-like Telomeric PML Localization
Mangosh TL, Awadallah WN, Grabowska MM, Taylor DJ.
Mol Cancer Res, 2021
10.1158/1541-7786.MCR-20-0314

EFA6A, an exchange factor for Arf6, regulates early steps in ciliogenesis
Partisani M, Baron CL, Ghossoub R, Fayad R, Pagnotta S, Abélanet S, Macia E, Brau F, Lacas-Gervais S, Benmerah A, Luton F, Franco M.
J Cell Sci, 2021
10.1242/jcs.249565

Intercellular and intracellular cilia orientation is coordinated by CELSR1 and CAMSAP3 in oviduct multiciliated cells
Usami FM, Arata M, Shi D, Oka S, Higuchi Y, Tissir F, Takeichi M, Fujimori T.
J Cell Sci, 2021
10.1242/jcs.257006

LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformation
von Appen A, LaJoie D, Johnson IE, Trnka MJ, Pick SM, Burlingame AL, Ullman KS, Frost A.
Nature, 2020
10.1038/s41586-020-2232-x

Thermus thermophilus Argonaute Functions in the Completion of DNA Replication
Jolly SM, Gainetdinov I, Jouravleva K, Zhang H, Strittmatter L, Bailey SM, Hendricks GM, Dhabaria A, Ueberheide B, Zamore PD.
Cell, 2020
10.1016/j.cell.2020.07.036

A general strategy to develop cell permeable and fluorogenic probes for multicolour nanoscopy
Wang L, Tran M, D'Este E, Roberti J, Koch B, Xue L, Johnsson K.
Nat Chem, 2020
10.1038/s41557-019-0371-1

Microglia and macrophages promote corralling, wound compaction and recovery after spinal cord injury via Plexin-B2
Zhou X, Wahane S, Friedl MS, Kluge M, Friedel CC, Avrampou K, Zachariou V, Guo L, Zhang B, He X, Friedel RH, Zou H.
Nat Neurosci, 2020
10.1038/s41593-020-0597-7

Cell stretching is amplified by active actin remodelling to deform and recruit proteins in mechanosensitive structures
Massou S, Nunes Vicente F, Wetzel F, Mehidi A, Strehle D, Leduc C, Voituriez R, Rossier O, Nassoy P, Giannone G.
Nat Cell Biol, 2020
10.1038/s41556-020-0548-2

Mitochondrial RNA granules are fluid condensates positioned by membrane dynamics
Rey T, Zaganelli S, Cuillery E, Vartholomaiou E, Croisier M, Martinou JC, Manley S.
Nat Cell Biol, 2020
10.1038/s41556-020-00584-8

Combination of metabolic intervention and T cell therapy enhances solid tumor immunotherapy
Hao M, Hou S, Li W, Li K, Xue L, Hu Q, Zhu L, Chen Y, Sun H, Ju C, Zhang C.
Sci Transl Med, 2020
10.1126/scitranslmed.aaz6667

Cholesterol in the Viral Membrane is a Molecular Switch Governing HIV-1 Env Clustering
Nieto-Garai JA, Arboleya A, Otaegi S, Chojnacki J, Casas J, Fabriàs G, Contreras FX, Kräusslich HG, Lorizate M.
Adv Sci, 2020
10.1002/advs.202003468

Arginine-Enriched Mixed-Charge Domains Provide Cohesion for Nuclear Speckle Condensation
Greig JA, Nguyen TA, Lee M, Holehouse AS, Posey AE, Pappu RV, Jedd G.
Mol Cell, 2020
10.1016/j.molcel.2020.01.025

Regulation of Phosphoribosyl-Linked Serine Ubiquitination by Deubiquitinases DupA and DupB
Shin D, Mukherjee R, Liu Y, Gonzalez A, Bonn F, Liu Y, Rogov VV, Heinz M, Stolz A, Hummer G, Dötsch V, Luo ZQ, Bhogaraju S, Dikic I.
Mol Cell, 2020
10.1016/j.molcel.2019.10.019

The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation
Huo X, Ji L, Zhang Y, Lv P, Cao X, Wang Q, Yan Z, Dong S, Du D, Zhang F, Wei G, Liu Y, Wen B.
Mol Cell, 2020
10.1016/j.molcel.2019.10.001

In Situ, Noncovalent Labeling and Stimulated Emission Depletion-Based Super-Resolution Imaging of Supramolecular Peptide Nanostructures
Kumar M, Son J, Huang RH, Sementa D, Lee M, O'Brien S, Ulijn RV.
ACS Nano, 2020
10.1021/acsnano.0c05029

Neural Stem Cells Direct Axon Guidance via Their Radial Fiber Scaffold
Kaur N, Han W, Li Z, Madrigal MP, Shim S, Pochareddy S, Gulden FO, Li M, Xu X, Xing X, Takeo Y, Li Z, Lu K, Imamura Kawasawa Y, Ballester-Lurbe B, Moreno-Bravo JA, Chédotal A, Terrado J, Pérez-Roger I, Koleske AJ, Sestan N.
Neuron, 2020
10.1016/j.neuron.2020.06.035

Artificial regulation of state transition for augmenting plant photosynthesis using synthetic light-harvesting polymer materials
Zhou X, Zeng Y, Tang Y, Huang Y, Lv F, Liu L, Wang S.
Sci Adv, 2020
10.1126/sciadv.abc5237

MCART1/SLC25A51 is required for mitochondrial NAD transport
Kory N, Uit de Bos J, van der Rijt S, Jankovic N, Güra M, Arp N, Pena IA, Prakash G, Chan SH, Kunchok T, Lewis CA, Sabatini DM.
Sci Adv, 2020
10.1126/sciadv.abe5310

Ribosome-associated vesicles: A dynamic subcompartment of the endoplasmic reticulum in secretory cells
Carter SD, Hampton CM, Langlois R, Melero R, Farino ZJ, Calderon MJ, Li W, Wallace CT, Tran NH, Grassucci RA, Siegmund SE, Pemberton J, Morgenstern TJ, Eisenman L, Aguilar JI, Greenberg NL, Levy ES, Yi E, Mitchell WG, Rice WJ, Wigge C, Pilli J, George EW, Aslanoglou D, Courel M, Freyberg RJ, Javitch JA, Wills ZP, Area-Gomez E, Shiva S, Bartolini F, Volchuk A, Murray SA, Aridor M, Fish KN, Walter P, Balla T, Fass D, Wolf SG, Watkins SC, Carazo JM, Jensen GJ, Frank J, Freyberg Z.
Sci Adv, 2020
10.1126/sciadv.aay9572

The chaperonin CCT controls T cell receptor-driven 3D configuration of centrioles
Martin-Cofreces NB, Chichon FJ, Calvo E, Torralba D, Bustos-Moran E, Dosil SG, Rojas-Gomez A, Bonzon-Kulichenko E, Lopez JA, Otón J, Sorrentino A, Zabala JC, Vernos I, Vazquez J, Valpuesta JM, Sanchez-Madrid F.
Sci Adv, 2020
10.1126/sciadv.abb7242

A Multi-responsive Fluorescent Probe Reveals Mitochondrial Nucleoprotein Dynamics with Reactive Oxygen Species Regulation through Super-resolution Imaging
Yang G, Liu Z, Zhang R, Tian X, Chen J, Han G, Liu B, Han X, Fu Y, Hu Z, Zhang Z.
Angew Chem Int Ed Engl, 2020
10.1002/anie.202005959

Designing Sub-2 nm Organosilica Nanohybrids for Far-Field Super-Resolution Imaging
Liang L, Yan W, Qin X, Peng X, Feng H, Wang Y, Zhu Z, Liu L, Han Y, Xu Q, Qu J, Liu X.
Angew Chem Int Ed Engl, 2020
10.1002/anie.201912404

Endosome motility defects revealed at super-resolution in live cells using HIDE probes
Gupta A, Rivera-Molina F, Xi Z, Toomre D, Schepartz A.
Nat Chem Biol, 2020
10.1038/s41589-020-0479-z

A HaloTag-TEV genetic cassette for mechanical phenotyping of proteins from tissues
Rivas-Pardo JA, Li Y, Mártonfalvi Z, Tapia-Rojo R, Unger A, Fernández-Trasancos Á, Herrero-Galán E, Velázquez-Carreras D, Fernández JM, Linke WA, Alegre-Cebollada J.
Nat Commun, 2020
10.1038/s41467-020-15465-9

A set of monomeric near-infrared fluorescent proteins for multicolor imaging across scales
Matlashov ME, Shcherbakova DM, Alvelid J, Baloban M, Pennacchietti F, Shemetov AA, Testa I, Verkhusha VV.
Nat Commun, 2020
10.1038/s41467-019-13897-6

A signaling hub of insulin receptor, dystrophin glycoprotein complex and plakoglobin regulates muscle size
Eid Mutlak Y, Aweida D, Volodin A, Ayalon B, Dahan N, Parnis A, Cohen S.
Nat Commun, 2020
10.1038/s41467-020-14895-9

Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging
Li H, Yang J, Tian C, Diao M, Wang Q, Zhao S, Li S, Tan F, Hua T, Qin Y, Lin CP, Deska-Gauthier D, Thompson GJ, Zhang Y, Shui W, Liu ZJ, Wang T, Zhong G.
Nat Commun, 2020
10.1038/s41467-020-19510-5

Cytokinetic bridge triggers de novo lumen formation in vivo
Rathbun LI, Colicino EG, Manikas J, O'Connell J, Krishnan N, Reilly NS, Coyne S, Erdemci-Tandogan G, Garrastegui A, Freshour J, Santra P, Manning ML, Amack JD, Hehnly H.
Nat Commun, 2020
10.1038/s41467-020-15002-8

Light microscopy of proteins in their ultrastructural context
M'Saad O, Bewersdorf J.
Nat Commun, 2020
10.1038/s41467-020-17523-8

Mitochondrial dynamics quantitatively revealed by STED nanoscopy with an enhanced squaraine variant probe
Yang X, Yang Z, Wu Z, He Y, Shan C, Chai P, Ma C, Tian M, Teng J, Jin D, Yan W, Das P, Qu J, Xi P.
Nat Commun, 2020
10.1038/s41467-020-17546-1

Plasma-derived extracellular vesicles from Plasmodium vivax patients signal spleen fibroblasts via NF-kB facilitating parasite cytoadherence
Toda H, Diaz-Varela M, Segui-Barber J, Roobsoong W, Baro B, Garcia-Silva S, Galiano A, Gualdrón-López M, Almeida ACG, Brito MAM, de Melo GC, Aparici-Herraiz I, Castro-Cavadía C, Monteiro WM, Borràs E, Sabidó E, Almeida IC, Chojnacki J, Martinez-Picado J, Calvo M, Armengol P, Carmona-Fonseca J, Yasnot MF, Lauzurica R, Marcilla A, Peinado H, Galinski MR, Lacerda MVG, Sattabongkot J, Fernandez-Becerra C, Del Portillo HA.
Nat Commun, 2020
10.1038/s41467-020-16337-y

Resolution of R-loops by INO80 promotes DNA replication and maintains cancer cell proliferation and viability
Prendergast L, McClurg UL, Hristova R, Berlinguer-Palmini R, Greener S, Veitch K, Hernandez I, Pasero P, Rico D, Higgins JMG, Gospodinov A, Papamichos-Chronakis M.
Nat Commun, 2020
10.1038/s41467-020-18306-x

Systemic brain tumor delivery of synthetic protein nanoparticles for glioblastoma therapy
Gregory JV, Kadiyala P, Doherty R, Cadena M, Habeel S, Ruoslahti E, Lowenstein PR, Castro MG, Lahann J.
Nat Commun, 2020
10.1038/s41467-020-19225-7

The role of Mediator and Little Elongation Complex in transcription termination
Takahashi H, Ranjan A, Chen S, Suzuki H, Shibata M, Hirose T, Hirose H, Sasaki K, Abe R, Chen K, He Y, Zhang Y, Takigawa I, Tsukiyama T, Watanabe M, Fujii S, Iida M, Yamamoto J, Yamaguchi Y, Suzuki Y, Matsumoto M, Nakayama KI, Washburn MP, Saraf A, Florens L, Sato S, Tomomori-Sato C, Conaway RC, Conaway JW, Hatakeyama S.
Nat Commun, 2020
10.1038/s41467-020-14849-1

T-Plastin reinforces membrane protrusions to bridge matrix gaps during cell migration
Garbett D, Bisaria A, Yang C, McCarthy DG, Hayer A, Moerner WE, Svitkina TM, Meyer T.
Nat Commun, 2020
10.1038/s41467-020-18586-3

Two-color nanoscopy of organelles for extended times with HIDE probes
Chu L, Tyson J, Shaw JE, Rivera-Molina F, Koleske AJ, Schepartz A, Toomre DK.
Nat Commun, 2020
10.1038/s41467-020-17859-1

Wipi3 is essential for alternative autophagy and its loss causes neurodegeneration
Yamaguchi H, Honda S, Torii S, Shimizu K, Katoh K, Miyake K, Miyake N, Fujikake N, Sakurai HT, Arakawa S, Shimizu S.
Nat Commun, 2020
10.1038/s41467-020-18892-w

PLA2G1B is involved in CD4 anergy and CD4 lymphopenia in HIV-infected patients
Pothlichet J, Rose T, Bugault F, Jeammet L, Meola A, Haouz A, Saul F, Geny D, Alcami J, Ruiz-Mateos E, Teyton L, Lambeau G, Thèze J.
J Clin Invest, 2020
10.1172/JCI131842

Chloride intracellular channel 1 cooperates with potassium channel EAG2 to promote medulloblastoma growth
Francisco MA, Wanggou S, Fan JJ, Dong W, Chen X, Momin A, Abeysundara N, Min HK, Chan J, McAdam R, Sia M, Pusong RJ, Liu S, Patel N, Ramaswamy V, Kijima N, Wang LY, Song Y, Kafri R, Taylor MD, Li X, Huang X.
J Exp Med, 2020
10.1084/jem.20190971

A comparative analysis of the mobility of 45 proteins in the synaptic bouton
Reshetniak S, Ußling JE, Perego E, Rammner B, Schikorski T, Fornasiero EF, Truckenbrodt S, Köster S, Rizzoli SO.
EMBO J, 2020
10.15252/embj.2020104596

Covalent Self-Labeling of Tagged Proteins with Chemical Fluorescent Dyes in BY-2 Cells and Arabidopsis Seedlings
Iwatate RJ, Yoshinari A, Yagi N, Grzybowski M, Ogasawara H, Kamiya M, Komatsu T, Taki M, Yamaguchi S, Frommer WB, Nakamura M.
Plant Cell, 2020
10.1105/tpc.20.00439

Mechanisms of Motor-Independent Membrane Remodeling Driven by Dynamic Microtubules
Rodríguez-García R, Volkov VA, Chen CY, Katrukha EA, Olieric N, Aher A, Grigoriev I, López MP, Steinmetz MO, Kapitein LC, Koenderink G, Dogterom M, Akhmanova A.
Curr Biol, 2020
10.1016/j.cub.2020.01.036

Microtubule Minus-End Binding Protein CAMSAP2 and Kinesin-14 Motor KIFC3 Control Dendritic Microtubule Organization
Cao Y, Lipka J, Stucchi R, Burute M, Pan X, Portegies S, Tas R, Willems J, Will L, MacGillavry H, Altelaar M, Kapitein LC, Harterink M, Hoogenraad CC.
Curr Biol, 2020
10.1016/j.cub.2019.12.056

UBAP2L Forms Distinct Cores that Act in Nucleating Stress Granules Upstream of G3BP1
Cirillo L, Cieren A, Barbieri S, Khong A, Schwager F, Parker R, Gotta M.
Curr Biol, 2020
10.1016/j.cub.2019.12.020

Chlamydia-induced curvature of the host-cell plasma membrane is required for infection
Hänsch S, Spona D, Murra G, Köhrer K, Subtil A, Furtado AR, Lichtenthaler SF, Dislich B, Mölleken K, Hegemann JH.
PNAS, 2020
10.1073/pnas.1911528117

The structure of helical lipoprotein lipase reveals an unexpected twist in lipase storage
Gunn KH, Roberts BS, Wang F, Strauss JD, Borgnia MJ, Egelman EH, Neher SB.
PNAS, 2020
10.1073/pnas.1916555117

LIM-Nebulette Reinforces Podocyte Structural Integrity by Linking Actin and Vimentin Filaments
Ge X, Zhang T, Yu X, Muwonge AN, Anandakrishnan N, Wong NJ, Haydak JC, Reid JM, Fu J, Wong JS, Bhattacharya S, Cuttitta CM, Zhong F, Gordon RE, Salem F, Janssen W, Hone JC, Zhang A, Li H, He JC, Gusella GL, Campbell KN, Azeloglu EU.
J Am Soc Nephrol, 2020
10.1681/ASN.2019121261

Arginase 2 is a mediator of ischemia-reperfusion injury in the kidney through regulation of nitrosative stress
Hara M, Torisu K, Tomita K, Kawai Y, Tsuruya K, Nakano T, Kitazono T.
Kidney Int, 2020
10.1016/j.kint.2020.03.032

A modified lysosomal organelle mediates nonlytic egress of reovirus
Fernández de Castro I, Tenorio R, Ortega-González P, Knowlton JJ, Zamora PF, Lee CH, Fernández JJ, Dermody TS, Risco C.
J Cell Biol, 2020
10.1083/jcb.201910131

Distinct roles for luminal acidification in apical protein sorting and trafficking in zebrafish
Levic DS, Ryan S, Marjoram L, Honeycutt J, Bagwell J, Bagnat M.
J Cell Biol, 2020
10.1083/jcb.201908225

GRAF2, WDR44, and MICAL1 mediate Rab8/10/11-dependent export of E-cadherin, MMP14, and CFTR ΔF508
Lucken-Ardjomande Häsler S, Vallis Y, Pasche M, McMahon HT.
J Cell Biol, 2020
10.1083/jcb.201811014

Identification of novel synaptonemal complex components in C. elegans
Hurlock ME, Čavka I, Kursel LE, Haversat J, Wooten M, Nizami Z, Turniansky R, Hoess P, Ries J, Gall JG, Rog O, Köhler S, Kim Y.
J Cell Biol, 2020
10.1083/jcb.201910043

Mitochondrial DNA segregation and replication restrict the transmission of detrimental mutation
Chen Z, Wang ZH, Zhang G, Bleck CKE, Chung DJ, Madison GP, Lindberg E, Combs C, Balaban RS, Xu H.
J Cell Biol, 2020
10.1083/jcb.201905160

Nanoscopy reveals the layered organization of the sarcomeric H-zone and I-band complexes
Szikora S, Gajdos T, Novák T, Farkas D, Földi I, Lenart P, Erdélyi M, Mihály J.
J Cell Biol, 2020
10.1083/jcb.201907026

Deep-Red Fluorescent Organic Nanoparticles with High Brightness and Photostability for Super-Resolution in Vitro and in Vivo Imaging Using STED Nanoscopy
Xu Y, Zhang H, Zhang N, Wang X, Dang D, Jing X, Xi D, Hao Y, Tang BZ, Meng L.
ACS Appl Mater Interfaces, 2020
10.1021/acsami.9b18336

Synergistic Features of Superoxide Molecule Anchoring and Charge Transfer on Two-Dimensional Ti(3)C(2)T(x) MXene for Efficient Peroxymonosulfate Activation
Ding M, Chen W, Xu H, Lu C, Lin T, Shen Z, Tao H, Zhang K.
ACS Appl Mater Interfaces, 2020
10.1021/acsami.9b20530

Autophagic degradation of HAS2 in endothelial cells: A novel mechanism to regulate angiogenesis
Chen CG, Gubbiotti MA, Kapoor A, Han X, Yu Y, Linhardt RJ, Iozzo RV.
Matrix Biol, 2020
10.1016/j.matbio.2020.02.001

Axon Growth of CNS Neurons in Three Dimensions Is Amoeboid and Independent of Adhesions
Santos TE, Schaffran B, Broguière N, Meyn L, Zenobi-Wong M, Bradke F.
Cell Rep, 2020
10.1016/j.celrep.2020.107907

CtBP1-Mediated Membrane Fission Contributes to Effective Recycling of Synaptic Vesicles
Ivanova D, Imig C, Camacho M, Reinhold A, Guhathakurta D, Montenegro-Venegas C, Cousin MA, Gundelfinger ED, Rosenmund C, Cooper B, Fejtova A.
Cell Rep, 2020
10.1016/j.celrep.2020.01.079

Dynamin-2 Regulates Postsynaptic Cytoskeleton Organization and Neuromuscular Junction Development
Lin SS, Hsieh TL, Liou GG, Li TN, Lin HC, Chang CW, Wu HY, Yao CK, Liu YW.
Cell Rep, 2020
10.1016/j.celrep.2020.108310

ELKS1 Captures Rab6-Marked Vesicular Cargo in Presynaptic Nerve Terminals
Nyitrai H, Wang SSH, Kaeser PS.
Cell Rep, 2020
10.1016/j.celrep.2020.107712

Flotillin-Dependent Membrane Microdomains Are Required for Functional Phagolysosomes against Fungal Infections
Schmidt F, Thywißen A, Goldmann M, Cunha C, Cseresnyés Z, Schmidt H, Rafiq M, Galiani S, Gräler MH, Chamilos G, Lacerda JF, Campos A Jr, Eggeling C, Figge MT, Heinekamp T, Filler SG, Carvalho A, Brakhage AA.
Cell Rep, 2020
10.1016/j.celrep.2020.108017

Intersectin-Mediated Clearance of SNARE Complexes Is Required for Fast Neurotransmission
Jäpel M, Gerth F, Sakaba T, Bacetic J, Yao L, Koo SJ, Maritzen T, Freund C, Haucke V.
Cell Rep, 2020
10.1016/j.celrep.2019.12.035

Neuronal BIN1 Regulates Presynaptic Neurotransmitter Release and Memory Consolidation
De Rossi P, Nomura T, Andrew RJ, Masse NY, Sampathkumar V, Musial TF, Sudwarts A, Recupero AJ, Le Metayer T, Hansen MT, Shim HN, Krause SV, Freedman DJ, Bindokas VP, Kasthuri N, Nicholson DA, Contractor A, Thinakaran G.
Cell Rep, 2020
10.1016/j.celrep.2020.02.026

Stabilization of Endothelial Receptor Arrays by a Polarized Spectrin Cytoskeleton Facilitates Rolling and Adhesion of Leukocytes
Mylvaganam S, Riedl M, Vega A, Collins RF, Jaqaman K, Grinstein S, Freeman SA.
Cell Rep, 2020
10.1016/j.celrep.2020.107798

Vesicle Shrinking and Enlargement Play Opposing Roles in the Release of Exocytotic Contents
Shin W, Arpino G, Thiyagarajan S, Su R, Ge L, McDargh Z, Guo X, Wei L, Shupliakov O, Jin A, O'Shaughnessy B, Wu LG.
Cell Rep, 2020
10.1016/j.celrep.2019.12.044

Integrin α6 signaling induces STAT3-TET3-mediated hydroxymethylation of genes critical for maintenance of glioma stem cells
Herrmann A, Lahtz C, Song J, Aftabizadeh M, Cherryholmes GA, Xin H, Adamus T, Lee H, Grunert D, Armstrong B, Chu P, Brown C, Lim M, Forman S, Yu H.
Oncogene, 2020
10.1038/s41388-019-1134-6

Cristae undergo continuous cycles of membrane remodelling in a MICOS-dependent manner
Kondadi AK, Anand R, Hänsch S, Urbach J, Zobel T, Wolf DM, Segawa M, Liesa M, Shirihai OS, Weidtkamp-Peters S, Reichert AS.
EMBO Rep, 2020
10.15252/embr.201949776

βH-spectrin is required for ratcheting apical pulsatile constrictions during tissue invagination
Krueger D, Pallares Cartes C, Makaske T, De Renzis S.
EMBO Rep, 2020
10.15252/embr.201949858

Actin assembly ruptures the nuclear envelope by prying the lamina away from nuclear pores and nuclear membranes in starfish oocytes
Wesolowska N, Avilov I, Machado P, Geiss C, Kondo H, Mori M, Lenart P.
Elife, 2020
10.7554/eLife.49774

Alstrom syndrome gene is a stem-cell-specific regulator of centriole duplication in the Drosophila testis
Chen C, Yamashita YM.
Elife, 2020
10.7554/eLife.59368

Essential function of the alveolin network in the subpellicular microtubules and conoid assembly in Toxoplasma gondii
Tosetti N, Dos Santos Pacheco N, Bertiaux E, Maco B, Bournonville L, Hamel V, Guichard P, Soldati-Favre D.
Elife, 2020
10.7554/eLife.56635

Genome-wide alterations of uracil distribution patterns in human DNA upon chemotherapeutic treatments
Pálinkás HL, Békési A, Róna G, Pongor L, Papp G, Tihanyi G, Holub E, Póti Á, Gemma C, Ali S, Morten MJ, Rothenberg E, Pagano M, Szűts D, Győrffy B, Vértessy BG.
Elife, 2020
10.7554/eLife.60498

The membrane periodic skeleton is an actomyosin network that regulates axonal diameter and conduction
Costa AR, Sousa SC, Pinto-Costa R, Mateus JC, Lopes CD, Costa AC, Rosa D, Machado D, Pajuelo L, Wang X, Zhou FQ, Pereira AJ, Sampaio P, Rubinstein BY, Mendes Pinto I, Lampe M, Aguiar P, Sousa MM.
Elife, 2020
10.7554/eLife.55471

β spectrin-dependent and domain specific mechanisms for Na(+) channel clustering
Liu CH, Seo R, Ho TS, Stankewich M, Mohler PJ, Hund TJ, Noebels JL, Rasband MN.
Elife, 2020
10.7554/eLife.56629

Correlating STED and synchrotron XRF nano-imaging unveils cosegregation of metals and cytoskeleton proteins in dendrites
Domart F, Cloetens P, Roudeau S, Carmona A, Verdier E, Choquet D, Ortega R.
Elife, 2020
10.7554/eLife.62334

ORANGE: A CRISPR/Cas9-based genome editing toolbox for epitope tagging of endogenous proteins in neurons
Willems J, de Jong APH, Scheefhals N, Mertens E, Catsburg LAE, Poorthuis RB, de Winter F, Verhaagen J, Meye FJ, MacGillavry HD.
PLoS Biol, 2020
10.1371/journal.pbio.3000665

Improving Brightness and Stability of Si-Rhodamine for Super-Resolution Imaging of Mitochondria in Living Cells
Song Y, Zhang X, Shen Z, Yang W, Wei J, Li S, Wang X, Li X, He Q, Zhang S, Zhang Q, Gao B.
Anal Chem, 2020
10.1021/acs.analchem.9b04926

Tumor necrosis factor alpha mediates neuromuscular synapse elimination
Fu XQ, Peng J, Wang AH, Luo ZG.
Cell Discov, 2020
10.1038/s41421-020-0143-5

A novel water-soluble quinoline-indole derivative as a three-photon fluorescent probe for identifying nucleolus RNA and mitochondrial DNA
Elhussin IEH, Zhang S, Liu J, Li D, Zhang Q, Li S, Tian X, Wu J, Tian Y.
Chem Commun, 2020
10.1039/c9cc09640j

Microscope laser assisted photooxidative activation of bioorthogonal ClickOx probes
Kormos A , Kern D , Egyed A , Söveges B , Németh K , Kele P .
Chem Commun, 2020
10.1039/d0cc01512a

Role of the Sec22b-E-Syt complex in neurite growth and ramification
Gallo A, Danglot L, Giordano F, Hewlett B, Binz T, Vannier C, Galli T.
J Cell Sci, 2020
10.1242/jcs.247148

The cortical actin network regulates avidity-dependent binding of hyaluronan by the lymphatic vessel endothelial receptor LYVE-1
Stanly TA, Fritzsche M, Banerji S, Shrestha D, Schneider F, Eggeling C, Jackson DG.
J Biol Chem, 2020
10.1074/jbc.RA119.011992

Rho-kinase inhibition by fasudil modulates pre-synaptic vesicle dynamics
Saal KA, Warth Pérez Arias C, Roser AE, Christoph Koch J, Bähr M, Rizzoli SO, Lingor P.
J Neurochem, 2020
10.1111/jnc.15274

Super resolution microscopy and deep learning identify Zika virus reorganization of the endoplasmic reticulum
Long RKM, Moriarty KP, Cardoen B, Gao G, Vogl AW, Jean F, Hamarneh G, Nabi IR.
Sci Rep, 2020
10.1038/s41598-020-77170-3

Coefficient of variation as an image-intensity metric for cytoskeleton bundling
Higaki T, Akita K, Katoh K.
Sci Rep, 2020
10.1038/s41598-020-79136-x

Vascular endothelial growth factor promotes atrial arrhythmias by inducing acute intercalated disk remodeling
Mezache L, Struckman HL, Greer-Short A, Baine S, Györke S, Radwański PB, Hund TJ, Veeraraghavan R.
Sci Rep, 2020
10.1038/s41598-020-77562-5

Impaired Mitochondrial Morphology and Functionality in Lonp1(wt/-) Mice
De Gaetano A, Gibellini L, Bianchini E, Borella R, De Biasi S, Nasi M, Boraldi F, Cossarizza A, Pinti M.
J Clin Med, 2020
10.3390/jcm9061783

High photon count rates improve the quality of super-resolution fluorescence fluctuation spectroscopy
Schneider F, Hernandez-Varas P, Christoffer Lagerholm B, Shrestha D, Sezgin E, Julia Roberti M, Ossato G, Hecht F, Eggeling C, Urbančič I.
J Phys Chem D, 2020
10.1088/1361-6463/ab6cca

STED nanoscopy of KK114-stained pathogenic bacteria
Lucidi M, Hristu R, Nichele L, Stanciu GA, Tranca DE, Holban AM, Visca P, Stanciu SG, Cincotti G.
J Biophotonics, 2020
10.1002/jbio.202000097

Chimeric peptidomimetic antibiotics against Gram-negative bacteria
Luther A, Urfer M, Zahn M, Müller M, Wang SY, Mondal M, Vitale A, Hartmann JB, Sharpe T, Monte FL, Kocherla H, Cline E, Pessi G, Rath P, Modaresi SM, Chiquet P, Stiegeler S, Verbree C, Remus T, Schmitt M, Kolopp C, Westwood MA, Desjonquères N, Brabet E, Hell S, LePoupon K, Vermeulen A, Jaisson R, Rithié V, Upert G, Lederer A, Zbinden P, Wach A, Moehle K, Zerbe K, Locher HH, Bernardini F, Dale GE, Eberl L, Wollscheid B, Hiller S, Robinson JA, Obrecht D.
Nature, 2019
10.1038/s41586-019-1665-6

Synaptic proximity enables NMDAR signalling to promote brain metastasis
Zeng Q, Michael IP, Zhang P, Saghafinia S, Knott G, Jiao W, McCabe BD, Galván JA, Robinson HPC, Zlobec I, Ciriello G, Hanahan D.
Nature, 2019
doi: 10.1038/s41586-019-1576-6

Local protein synthesis is a ubiquitous feature of neuronal pre- and postsynaptic compartments
Hafner AS, Donlin-Asp PG, Leitch B, Herzog E, Schuman EM.
Science, 2019
doi: 10.1126/science.aau3644

ApoE attenuates unresolvable inflammation by complex formation with activated C1q
Yin C, Ackermann S, Ma Z, Mohanta SK, Zhang C, Li Y, Nietzsche S, Westermann M, Peng L, Hu D, Bontha SV, Srikakulapu P, Beer M, Megens RTA, Steffens S, Hildner M, Halder LD, Eckstein HH, Pelisek J, Herms J, Roeber S, Arzberger T, Borodovsky A, Habenicht L, Binder CJ, Weber C, Zipfel PF, Skerka C, Habenicht AJR.
Nat Med, 2019
doi: 10.1038/s41591-018-0336-8

Deep learning enables cross-modality super-resolution in fluorescence microscopy
Wang H, Rivenson Y, Jin Y, Wei Z, Gao R, Günaydın H, Bentolila LA, Kural C, Ozcan A.
Nat Methods, 2019
doi: 10.1038/s41592-018-0239-0

Parameter-free image resolution estimation based on decorrelation analysis
Descloux A, Grußmayer KS, Radenovic A.
Nat Methods, 2019
10.1038/s41592-019-0515-7

An essential role for the Zn(2+) transporter ZIP7 in B cell development
Anzilotti C, Swan DJ, Boisson B, Deobagkar-Lele M, Oliveira C, Chabosseau P, Engelhardt KR, Xu X, Chen R, Alvarez L, Berlinguer-Palmini R, Bull KR, Cawthorne E, Cribbs AP, Crockford TL, Dang TS, Fearn A, Fenech EJ, de Jong SJ, Lagerholm BC, Ma CS, Sims D, van den Berg B, Xu Y, Cant AJ, Kleiner G, Leahy TR, de la Morena MT, Puck JM, Shapiro RS, van der Burg M, Chapman JR, Christianson JC, Davies B, McGrath JA, Przyborski S, Santibanez Koref M, Tangye SG, Werner A, Rutter GA, Padilla-Parra S, Casanova JL, Cornall RJ, Conley ME, Hambleton S.
Nat Immunol, 2019
doi: 10.1038/s41590-018-0295-8

The macrophage tetraspan MS4A4A enhances dectin-1-dependent NK cell-mediated resistance to metastasis
Mattiola I, Tomay F, De Pizzol M, Silva-Gomes R, Savino B, Gulic T, Doni A, Lonardi S, Astrid Boutet M, Nerviani A, Carriero R, Molgora M, Stravalaci M, Morone D, Shalova IN, Lee Y, Biswas SK, Mantovani G, Sironi M, Pitzalis C, Vermi W, Bottazzi B, Mantovani A, Locati M.
Nat Immunol, 2019
doi: 10.1038/s41590-019-0417-y

Lewy pathology in Parkinson's disease consists of crowded organelles and lipid membranes
Shahmoradian SH, Lewis AJ, Genoud C, Hench J, Moors TE, Navarro PP, Castaño-Díez D, Schweighauser G, Graff-Meyer A, Goldie KN, Sütterlin R, Huisman E, Ingrassia A, Gier Y, Rozemuller AJM, Wang J, Paepe A, Erny J, Staempfli A, Hoernschemeyer J, Großerüschkamp F, Niedieker D, El-Mashtoly SF, Quadri M, Van IJcken WFJ, Bonifati V, Gerwert K, Bohrmann B, Frank S, Britschgi M, Stahlberg H, Van de Berg WDJ, Lauer ME.
Nat Neurosci, 2019
doi: 10.1038/s41593-019-0423-2

Arginine Citrullination at the C-Terminal Domain Controls RNA Polymerase II Transcription
Sharma P, Lioutas A, Fernandez-Fuentes N, Quilez J, Carbonell-Caballero J, Wright RHG, Di Vona C, Le Dily F, Schüller R, Eick D, Oliva B, Beato M.
Mol Cell, 2019
doi: 10.1016/j.molcel.2018.10.016

Nascent Pre-rRNA Sorting via Phase Separation Drives the Assembly of Dense Fibrillar Components in the Human Nucleolus
Yao RW, Xu G, Wang Y, Shan L, Luan PF, Wang Y, Wu M, Yang LZ, Xing YH, Yang L, Chen LL.
Mol Cell, 2019
doi: 10.1016/j.molcel.2019.08.014

Using Nanoscopy To Probe the Biological Activity of Antimicrobial Leads That Display Potent Activity against Pathogenic, Multidrug Resistant, Gram-Negative Bacteria
Smitten KL, Southam HM, de la Serna JB, Gill MR, Jarman PJ, Smythe CGW, Poole RK, Thomas JA.
ACS Nano, 2019
doi: 10.1021/acsnano.8b08440

Feedback-Driven Assembly of the Axon Initial Segment
Fréal A, Rai D, Tas RP, Pan X, Katrukha EA, van de Willige D, Stucchi R, Aher A, Yang C, Altelaar AFM, Vocking K, Post JA, Harterink M, Kapitein LC, Akhmanova A, Hoogenraad CC.
Neuron, 2019
doi: 10.1016/j.neuron.2019.07.029

Granulovacuolar degeneration bodies are neuron-selective lysosomal structures induced by intracellular tau pathology
Wiersma VI, van Ziel AM, Vazquez-Sanchez S, Nölle A, Berenjeno-Correa E, Bonaterra-Pastra A, Clavaguera F, Tolnay M, Musters RJP, van Weering JRT, Verhage M, Hoozemans JJM, Scheper W.
Acta Neuropathol, 2019
doi: 10.1007/s00401-019-02046-4

Critical role of spectrin in hearing development and deafness
Liu Y, Qi J, Chen X, Tang M, Chu C, Zhu W, Li H, Tian C, Yang G, Zhong C, Zhang Y, Ni G, He S, Chai R, Zhong G.
Sci Adv, 2019
doi: 10.1126/sciadv.aav7803

JLP-centrosome is essential for the microtubule-mediated nucleocytoplasmic transport induced by extracellular stimuli
Lee CM, Aizawa K, Jiang J, Kung SKP, Jain R.
Sci Adv, 2019
doi: 10.1126/sciadv.aav0318

Protein-Specific, Multicolor and 3D STED Imaging in Cells with DNA-Labeled Antibodies
Spahn C, Hurter F, Glaesmann M, Karathanasis C, Lampe M, Heilemann M.
Angew Chem Int Ed Engl, 2019
doi: 10.1002/anie.201910115

Altered dendritic spine function and integration in a mouse model of fragile X syndrome
Booker SA, Domanski APF, Dando OR, Jackson AD, Isaac JTR, Hardingham GE, Wyllie DJA, Kind PC.
Nat Commun, 2019
doi: 10.1038/s41467-019-11891-6

Autophagy within the mushroom body protects from synapse aging in a non-cell autonomous manner
Bhukel A, Beuschel CB, Maglione M, Lehmann M, Juhász G, Madeo F, Sigrist SJ.
Nat Commun, 2019
doi: 10.1038/s41467-019-09262-2

Cellular responses to beating hydrogels to investigate mechanotransduction
Chandorkar Y, Castro Nava A, Schweizerhof S, Van Dongen M, Haraszti T, Köhler J, Zhang H, Windoffer R, Mourran A, Möller M, De Laporte L.
Nat Commun, 2019
doi: 10.1038/s41467-019-11475-4

CENP-A nucleosome clusters form rosette-like structures around HJURP during G1
Andronov L, Ouararhni K, Stoll I, Klaholz BP, Hamiche A.
Nat Commun, 2019
doi: 10.1038/s41467-019-12383-3

Dynamic constriction and fission of endoplasmic reticulum membranes by reticulon
Espadas J, Pendin D, Bocanegra R, Escalada A, Misticoni G, Trevisan T, Velasco Del Olmo A, Montagna A, Bova S, Ibarra B, Kuzmin PI, Bashkirov PV, Shnyrova AV, Frolov VA, Daga A.
Nat Commun, 2019
doi: 10.1038/s41467-019-13327-7

Functional role of PGAM5 multimeric assemblies and their polymerization into filaments
Ruiz K, Thaker TM, Agnew C, Miller-Vedam L, Trenker R, Herrera C, Ingaramo M, Toso D, Frost A, Jura N.
Nat Commun, 2019
doi: 10.1038/s41467-019-08393-w

GORAB scaffolds COPI at the trans-Golgi for efficient enzyme recycling and correct protein glycosylation
Witkos TM, Chan WL, Joensuu M, Rhiel M, Pallister E, Thomas-Oates J, Mould AP, Mironov AA, Biot C, Guerardel Y, Morelle W, Ungar D, Wieland FT, Jokitalo E, Tassabehji M, Kornak U, Lowe M.
Nat Commun, 2019
doi: 10.1038/s41467-018-08044-6

Mul1 restrains Parkin-mediated mitophagy in mature neurons by maintaining ER-mitochondrial contacts
Puri R, Cheng XT, Lin MY, Huang N, Sheng ZH.
Nat Commun, 2019
doi: 10.1038/s41467-019-11636-5

PKHD1L1 is a coat protein of hair-cell stereocilia and is required for normal hearing
Wu X, Ivanchenko MV, Al Jandal H, Cicconet M, Indzhykulian AA, Corey DP.
Nat Commun, 2019
doi: 10.1038/s41467-019-11712-w

Rapid active zone remodeling consolidates presynaptic potentiation
Böhme MA, McCarthy AW, Grasskamp AT, Beuschel CB, Goel P, Jusyte M, Laber D, Huang S, Rey U, Petzoldt AG, Lehmann M, Göttfert F, Haghighi P, Hell SW, Owald D, Dickman D, Sigrist SJ, Walter AM.
Nat Commun, 2019
doi: 10.1038/s41467-019-08977-6

Second messenger Ap(4)A polymerizes target protein HINT1 to transduce signals in FcεRI-activated mast cells
Yu J, Liu Z, Liang Y, Luo F, Zhang J, Tian C, Motzik A, Zheng M, Kang J, Zhong G, Liu C, Fang P, Guo M, Razin E, Wang J.
Nat Commun, 2019
doi: 10.1038/s41467-019-12710-8

The Cep57-pericentrin module organizes PCM expansion and centriole engagement
Watanabe K, Takao D, Ito KK, Takahashi M, Kitagawa D.
Nat Commun, 2019
doi: 10.1038/s41467-019-08862-2

The K219T-Lamin mutation induces conduction defects through epigenetic inhibition of SCN5A in human cardiac laminopathy
Salvarani N, Crasto S, Miragoli M, Bertero A, Paulis M, Kunderfranco P, Serio S, Forni A, Lucarelli C, Dal Ferro M, Larcher V, Sinagra G, Vezzoni P, Murry CE, Faggian G, Condorelli G, Di Pasquale E.
Nat Commun, 2019
doi: 10.1038/s41467-019-09929-w

Vimentin filaments interact with the actin cortex in mitosis allowing normal cell division
Duarte S, Viedma-Poyatos Á, Navarro-Carrasco E, Martínez AE, Pajares MA, Pérez-Sala D.
Nat Commun, 2019
doi: 10.1038/s41467-019-12029-4

ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-κB via phosphoinosotide remodeling of endosomes
Fang C, Manes TD, Liu L, Liu K, Qin L, Li G, Tobiasova Z, Kirkiles-Smith NC, Patel M, Merola J, Fu W, Liu R, Xie C, Tietjen GT, Nigrovic PA, Tellides G, Pober JS, Jane-Wit D.
Nat Commun, 2019
doi: 10.1038/s41467-019-10041-2

Asymmetric histone inheritance via strand-specific incorporation and biased replication fork movement
Wooten M, Snedeker J, Nizami ZF, Yang X, Ranjan R, Urban E, Kim JM, Gall J, Xiao J, Chen X.
Nat Struct Mol Biol, 2019
doi: 10.1038/s41594-019-0269-z

Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis
Weckbach LT, Grabmaier U, Uhl A, Gess S, Boehm F, Zehrer A, Pick R, Salvermoser M, Czermak T, Pircher J, Sorrelle N, Migliorini M, Strickland DK, Klingel K, Brinkmann V, Abu Abed U, Eriksson U, Massberg S, Brunner S, Walzog B.
J Exp Med, 2019
doi: 10.1084/jem.20181102

Loss of the ribosomal RNA methyltransferase NSUN5 impairs global protein synthesis and normal growth
Heissenberger C, Liendl L, Nagelreiter F, Gonskikh Y, Yang G, Stelzer EM, Krammer TL, Micutkova L, Vogt S, Kreil DP, Sekot G, Siena E, Poser I, Harreither E, Linder A, Ehret V, Helbich TH, Grillari-Voglauer R, Jansen-Dürr P, Koš M, Polacek N, Grillari J, Schosserer M.
Nucleic Acids Res, 2019
doi: 10.1093/nar/gkz1043

Cancer-Cell-Membrane-Coated Nanoparticles with a Yolk-Shell Structure Augment Cancer Chemotherapy
Nie D, Dai Z, Li J, Yang Y, Xi Z, Wang J, Zhang W, Qian K, Guo S, Zhu C, Wang R, Li Y, Yu M, Zhang X, Shi X, Gan Y.
Nano Lett, 2019
doi: 10.1021/acs.nanolett.9b03817

Dynamic Podosome-Like Structures in Nascent Phagosomes Are Coordinated by Phosphoinositides
Ostrowski PP, Freeman SA, Fairn G, Grinstein S.
Dev Cell, 2019
doi: 10.1016/j.devcel.2019.05.028

Multimerization and Retention of the Scavenger Receptor SR-B1 in the Plasma Membrane
Marques PE, Nyegaard S, Collins RF, Troise F, Freeman SA, Trimble WS, Grinstein S.
Dev Cell, 2019
doi: 10.1016/j.devcel.2019.05.026

F-actin patches associated with glutamatergic synapses control positioning of dendritic lysosomes
van Bommel B, Konietzny A, Kobler O, Bär J, Mikhaylova M.
EMBO J, 2019
doi: 10.15252/embj.2018101183

Individual cristae within the same mitochondrion display different membrane potentials and are functionally independent
Wolf DM, Segawa M, Kondadi AK, Anand R, Bailey ST, Reichert AS, van der Bliek AM, Shackelford DB, Liesa M, Shirihai OS.
EMBO J, 2019
doi: 10.15252/embj.2018101056

Length-independent telomere damage drives post-mitotic cardiomyocyte senescence
Anderson R, Lagnado A, Maggiorani D, Walaszczyk A, Dookun E, Chapman J, Birch J, Salmonowicz H, Ogrodnik M, Jurk D, Proctor C, Correia-Melo C, Victorelli S, Fielder E, Berlinguer-Palmini R, Owens A, Greaves LC, Kolsky KL, Parini A, Douin-Echinard V, LeBrasseur NK, Arthur HM, Tual-Chalot S, Schafer MJ, Roos CM, Miller JD, Robertson N, Mann J, Adams PD, Tchkonia T, Kirkland JL, Mialet-Perez J, Richardson GD, Passos JF.
EMBO J, 2019
doi: 10.15252/embj.2018100492

Multi-omics identify xanthine as a pro-survival metabolite for nematodes with mitochondrial dysfunction
Gioran A, Piazzesi A, Bertan F, Schroer J, Wischhof L, Nicotera P, Bano D.
EMBO J, 2019
doi: 10.15252/embj.201899558

Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration
Rusmini P, Cortese K, Crippa V, Cristofani R, Cicardi ME, Ferrari V, Vezzoli G, Tedesco B, Meroni M, Messi E, Piccolella M, Galbiati M, Garrè M, Morelli E, Vaccari T, Poletti A.
Autophagy, 2019
doi: 10.1080/15548627.2018.1535292

Kinesin-3 Responds to Local Microtubule Dynamics to Target Synaptic Cargo Delivery to the Presynapse
Guedes-Dias P, Nirschl JJ, Abreu N, Tokito MK, Janke C, Magiera MM, Holzbaur ELF.
Curr Biol, 2019
doi: 10.1016/j.cub.2018.11.065

RhoA Controls Axon Extension Independent of Specification in the Developing Brain
Dupraz S, Hilton BJ, Husch A, Santos TE, Coles CH, Stern S, Brakebusch C, Bradke F.
Curr Biol, 2019
doi: 10.1016/j.cub.2019.09.040

Daedalus and Gasz recruit Armitage to mitochondria, bringing piRNA precursors to the biogenesis machinery
Munafò M, Manelli V, Falconio FA, Sawle A, Kneuss E, Eastwood EL, Seah JWE, Czech B, Hannon GJ.
Genes Dev, 2019
doi: 10.1101/gad.325662.119

A photostable fluorescent marker for the superresolution live imaging of the dynamic structure of the mitochondrial cristae
Wang C, Taki M, Sato Y, Tamura Y, Yaginuma H, Okada Y, Yamaguchi S.
PNAS, 2019
doi: 10.1073/pnas.1905924116

Chemoptogenetic damage to mitochondria causes rapid telomere dysfunction
Qian W, Kumar N, Roginskaya V, Fouquerel E, Opresko PL, Shiva S, Watkins SC, Kolodieznyi D, Bruchez MP, Van Houten B.
PNAS, 2019
doi: 10.1073/pnas.1910574116

Growth factor stimulation promotes multivesicular endosome biogenesis by prolonging recruitment of the late-acting ESCRT machinery
Quinney KB, Frankel EB, Shankar R, Kasberg W, Luong P, Audhya A.
PNAS, 2019
doi: 10.1073/pnas.1817898116

Photoreceptor disc membranes are formed through an Arp2/3-dependent lamellipodium-like mechanism
Spencer WJ, Lewis TR, Phan S, Cady MA, Serebrovskaya EO, Schneider NF, Kim KY, Cameron LA, Skiba NP, Ellisman MH, Arshavsky VY.
PNAS, 2019
doi: 10.1073/pnas.1913518117

Resolving titin's lifecycle and the spatial organization of protein turnover in mouse cardiomyocytes
Rudolph F, Hüttemeister J, da Silva Lopes K, Jüttner R, Yu L, Bergmann N, Friedrich D, Preibisch S, Wagner E, Lehnart SE, Gregorio CC, Gotthardt M.
PNAS, 2019
doi: 10.1073/pnas.1904385116

Temperature- and rigidity-mediated rapid transport of lipid nanovesicles in hydrogels
Yu M, Song W, Tian F, Dai Z, Zhu Q, Ahmad E, Guo S, Zhu C, Zhong H, Yuan Y, Zhang T, Yi X, Shi X, Gan Y, Gao H.
PNAS, 2019
doi: 10.1073/pnas.1818924116

A cellular complex of BACE1 and γ-secretase sequentially generates Aβ from its full-length precursor
Liu L, Ding L, Rovere M, Wolfe MS, Selkoe DJ.
J Cell Biol, 2019
doi: 10.1083/jcb.201806205

A theory of centriole duplication based on self-organized spatial pattern formation
Takao D, Yamamoto S, Kitagawa D.
J Cell Biol, 2019
doi: 10.1083/jcb.201904156

Cross-linker-mediated regulation of actin network organization controls tissue morphogenesis
Krueger D, Quinkler T, Mortensen SA, Sachse C, De Renzis S.
J Cell Biol, 2019
doi: 10.1083/jcb.201811127

Dynamic nanoscale morphology of the ER surveyed by STED microscopy
Schroeder LK, Barentine AES, Merta H, Schweighofer S, Zhang Y, Baddeley D, Bewersdorf J, Bahmanyar S.
J Cell Biol, 2019
doi: 10.1083/jcb.201809107

ER-to-Golgi trafficking of procollagen in the absence of large carriers
McCaughey J, Stevenson NL, Cross S, Stephens DJ.
J Cell Biol, 2019
doi: 10.1083/jcb.201806035

Homeostatic scaling of active zone scaffolds maintains global synaptic strength
Goel P, Dufour Bergeron D, Böhme MA, Nunnelly L, Lehmann M, Buser C, Walter AM, Sigrist SJ, Dickman D.
J Cell Biol, 2019
doi: 10.1083/jcb.201807165

Imaging within single NPCs reveals NXF1's role in mRNA export on the cytoplasmic side of the pore
Ben-Yishay R, Mor A, Shraga A, Ashkenazy-Titelman A, Kinor N, Schwed-Gross A, Jacob A, Kozer N, Kumar P, Garini Y, Shav-Tal Y.
J Cell Biol, 2019
doi: 10.1083/jcb.201901127

Superresolution microscopy reveals linkages between ribosomal DNA on heterologous chromosomes
Potapova TA, Unruh JR, Yu Z, Rancati G, Li H, Stampfer MR, Gerton JL.
J Cell Biol, 2019
doi: 10.1083/jcb.201810166

Tks5 and Dynamin-2 enhance actin bundle rigidity in invadosomes to promote myoblast fusion
Chuang MC, Lin SS, Ohniwa RL, Lee GH, Su YA, Chang YC, Tang MJ, Liu YW.
J Cell Biol, 2019
doi: 10.1083/jcb.201809161

Structural evidence for a new elaborate 3D-organization of the cardiomyocyte lateral membrane in adult mammalian cardiac tissues
Guilbeau-Frugier C, Cauquil M, Karsenty C, Lairez O, Dambrin C, Payré B, Cassard H, Josse C, Seguelas MH, Allart S, Branchereau M, Heymes C, Mandel F, Delisle MB, Pathak A, Dague E, Sénard JM, Galés C.
Cardiovasc Res, 2019
doi: 10.1093/cvr/cvy256

EGFR Signaling Termination via Numb Trafficking in Ependymal Progenitors Controls Postnatal Neurogenic Niche Differentiation
Abdi K, Neves G, Pyun J, Kiziltug E, Ahrens A, Kuo CT.
Cell Rep, 2019
doi: 10.1016/j.celrep.2019.07.056

Presynaptic Endosomal Cathepsin D Regulates the Biogenesis of GABAergic Synaptic Vesicles
Li X, Qin L, Li Y, Yu H, Zhang Z, Tao C, Liu Y, Xue Y, Zhang X, Xu Z, Wang Y, Lou H, Tan Z, Saftig P, Chen Z, Xu T, Bi G, Duan S, Gao Z.
Cell Rep, 2019
doi: 10.1016/j.celrep.2019.06.006

The E3 Ubiquitin Ligase Mind Bomb 1 Controls Adenovirus Genome Release at the Nuclear Pore Complex
Bauer M, Flatt JW, Seiler D, Cardel B, Emmenlauer M, Boucke K, Suomalainen M, Hemmi S, Greber UF.
Cell Rep, 2019
doi: 10.1016/j.celrep.2019.11.064

Three-Dimensional Genomic Structure and Cohesin Occupancy Correlate with Transcriptional Activity during Spermatogenesis
Vara C, Paytuví-Gallart A, Cuartero Y, Le Dily F, Garcia F, Salvà-Castro J, Gómez-H L, Julià E, Moutinho C, Aiese Cigliano R, Sanseverino W, Fornas O, Pendás AM, Heyn H, Waters PD, Marti-Renom MA, Ruiz-Herrera A.
Cell Rep, 2019
doi: 10.1016/j.celrep.2019.06.037

Radial somatic F-actin organization affects growth cone dynamics during early neuronal development
Meka DP, Scharrenberg R, Zhao B, Kobler O, König T, Schaefer I, Schwanke B, Klykov S, Richter M, Eggert D, Windhorst S, Dotti CG, Kreutz MR, Mikhaylova M, Calderon de Anda F.
EMBO Rep, 2019
doi: 10.15252/embr.201947743

Viral M45 and necroptosis-associated proteins form heteromeric amyloid assemblies
Pham CL, Shanmugam N, Strange M, O'Carroll A, Brown JW, Sierecki E, Gambin Y, Steain M, Sunde M.
EMBO Rep, 2019
doi: 10.15252/embr.201846518

An integrin/MFG-E8 shuttle loads HIV-1 viral-like particles onto follicular dendritic cells in mouse lymph node
Park C, Kehrl JH.
Elife, 2019
doi: 10.7554/eLife.47776

Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and B cell activation
Bolger-Munro M, Choi K, Scurll JM, Abraham L, Chappell RS, Sheen D, Dang-Lawson M, Wu X, Priatel JJ, Coombs D, Hammer JA, Gold MR.
Elife, 2019
doi: 10.7554/eLife.44574

Reconstruction of Par-dependent polarity in apolar cells reveals a dynamic process of cortical polarization
Kono K, Yoshiura S, Fujita I, Okada Y, Shitamukai A, Shibata T, Matsuzaki F.
Elife, 2019
doi: 10.7554/eLife.45559

Release of cholesterol-rich particles from the macrophage plasma membrane during movement of filopodia and lamellipodia
Hu X, Weston TA, He C, Jung RS, Heizer PJ, Young BD, Tu Y, Tontonoz P, Wohlschlegel JA, Jiang H, Young SG, Fong LG.
Elife, 2019
doi: 10.7554/eLife.50231

Transient protein accumulation at the center of the T cell antigen-presenting cell interface drives efficient IL-2 secretion
Clark DJ, McMillan LE, Tan SL, Bellomo G, Massoue C, Thompson H, Mykhaylechko L, Alibhai D, Ruan X, Singleton KL, Du M, Hedges A, Schwartzberg PL, Verkade P, Murphy RF, Wülfing C.
Elife, 2019
doi: 10.7554/eLife.45789

Reticulon and CLIMP-63 regulate nanodomain organization of peripheral ER tubules
Gao G, Zhu C, Liu E, Nabi IR.
PLoS Biol, 2019
doi: 10.1371/journal.pbio.3000355

Dynamic organization of Herpesvirus glycoproteins on the viral envelope revealed by super-resolution microscopy
Beilstein F, Cohen GH, Eisenberg RJ, Nicolas V, Esclatine A, Pasdeloup D.
PLoS Pathog, 2019
doi: 10.1371/journal.ppat.1008209

The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2
Skjesol A, Yurchenko M, Bösl K, Gravastrand C, Nilsen KE, Grøvdal LM, Agliano F, Patane F, Lentini G, Kim H, Teti G, Kumar Sharma A, Kandasamy RK, Sporsheim B, Starheim KK, Golenbock DT, Stenmark H, McCaffrey M, Espevik T, Husebye H.
PLoS Pathog, 2019
doi: 10.1371/journal.ppat.1007684

ESCRT-III is necessary for the integrity of the nuclear envelope in micronuclei but is aberrant at ruptured micronuclear envelopes generating damage
Willan J, Cleasby AJ, Flores-Rodriguez N, Stefani F, Rinaldo C, Pisciottani A, Grant E, Woodman P, Bryant HE, Ciani B.
Oncogenesis, 2019
doi: 10.1038/s41389-019-0136-0

Ectopic Expression Induces Abnormal Somatodendritic Distribution of Tau in the Mouse Brain
Kubo A, Ueda S, Yamane A, Wada-Kakuda S, Narita M, Matsuyama M, Nomori A, Takashima A, Kato T, Onodera O, Goto M, Ito M, Tomiyama T, Mori H, Murayama S, Ihara Y, Misonou H, Miyasaka T.
J Neurosci, 2019
doi: 10.1523/JNEUROSCI.2845-18.2019

Presynaptic α(2)δ-2 Calcium Channel Subunits Regulate Postsynaptic GABA(A) Receptor Abundance and Axonal Wiring
Geisler S, Schöpf CL, Stanika R, Kalb M, Campiglio M, Repetto D, Traxler L, Missler M, Obermair GJ.
J Neurosci, 2019
doi: 10.1523/JNEUROSCI.2234-18.2019

Semaphorin4D Induces Inhibitory Synapse Formation by Rapid Stabilization of Presynaptic Boutons via MET Coactivation
Frias CP, Liang J, Bresser T, Scheefhals L, van Kesteren M, van Dorland R, Hu HY, Bodzeta A, van Bergen En Henegouwen PMP, Hoogenraad CC, Wierenga CJ.
J Neurosci, 2019
doi: 10.1523/JNEUROSCI.0215-19.2019

Aberrant accrual of BIN1 near Alzheimer's disease amyloid deposits in transgenic models
De Rossi P, Andrew RJ, Musial TF, Buggia-Prevot V, Xu G, Ponnusamy M, Ly H, Krause SV, Rice RC, de l'Estoile V, Valin T, Salem S, Despa F, Borchelt DR, Bindokas VP, Nicholson DA, Thinakaran G.
Brain Pathol, 2019
doi: 10.1111/bpa.12687

A mutant form of Dmc1 that bypasses the requirement for accessory protein Mei5-Sae3 reveals independent activities of Mei5-Sae3 and Rad51 in Dmc1 filament stability
Reitz D, Grubb J, Bishop DK.
PLoS Genet, 2019
doi: 10.1371/journal.pgen.1008217

Mitochondrial fusion is required for regulation of mitochondrial DNA replication
Silva Ramos E, Motori E, Brüser C, Kühl I, Yeroslaviz A, Ruzzenente B, Kauppila JHK, Busch JD, Hultenby K, Habermann BH, Jakobs S, Larsson NG, Mourier A.
PLoS Genet, 2019
doi: 10.1371/journal.pgen.1008085

A SEPT1-based scaffold is required for Golgi integrity and function
Song K, Gras C, Capin G, Gimber N, Lehmann M, Mohd S, Puchkov D, Rödiger M, Wilhelmi I, Daumke O, Schmoranzer J, Schürmann A, Krauss M.
J Cell Sci, 2019
doi: 10.1242/jcs.225557

Drosophila Ptp4E regulates vesicular packaging for monoamine-neuropeptide co-transmission
Tao J, Bulgari D, Berkhoudt DA, Calderon MJ, Watkins SC, Fonseca Velez HJ, Sabeva N, Deitcher DL, Levitan ES.
J Cell Sci, 2019
doi: 10.1242/jcs.224568

HsSAS-6-dependent cartwheel assembly ensures stabilization of centriole intermediates
Yoshiba S, Tsuchiya Y, Ohta M, Gupta A, Shiratsuchi G, Nozaki Y, Ashikawa T, Fujiwara T, Natsume T, Kanemaki MT, Kitagawa D.
J Cell Sci, 2019
doi: 10.1242/jcs.217521

Myosin V regulates synaptopodin clustering and localization in the dendrites of hippocampal neurons
Konietzny A, González-Gallego J, Bär J, Perez-Alvarez A, Drakew A, Demmers JAA, Dekkers DHW, Hammer JA 3rd, Frotscher M, Oertner TG, Wagner W, Kneussel M, Mikhaylova M.
J Cell Sci, 2019
doi: 10.1242/jcs.230177

Phosphorylation of the Bruchpilot N-terminus in Drosophila unlocks axonal transport of active zone building blocks
Driller JH, Lützkendorf J, Depner H, Siebert M, Kuropka B, Weise C, Piao C, Petzoldt AG, Lehmann M, Stelzl U, Zahedi R, Sickmann A, Freund C, Sigrist SJ, Wahl MC.
J Cell Sci, 2019
doi: 10.1242/jcs.225151

Epidermal growth factor (EGF) triggers nuclear calcium signaling through the intranuclear phospholipase Cδ-4 (PLCδ4)
de Miranda MC, Rodrigues MA, de Angelis Campos AC, Faria JAQA, Kunrath-Lima M, Mignery GA, Schechtman D, Goes AM, Nathanson MH, Gomes DA.
J Biol Chem, 2019
doi: 10.1074/jbc.RA118.006961

Mitochondrial fatty acid oxidation and the electron transport chain comprise a multifunctional mitochondrial protein complex
Wang Y, Palmfeldt J, Gregersen N, Makhov AM, Conway JF, Wang M, McCalley SP, Basu S, Alharbi H, St Croix C, Calderon MJ, Watkins S, Vockley J.
J Biol Chem, 2019
doi: 10.1074/jbc.RA119.008680

Neurolastin, a dynamin family GTPase, translocates to mitochondria upon neuronal stress and alters mitochondrial morphology in vivo
Lomash RM, Petralia RS, Holtzclaw LA, Tsuda MC, Wang YX, Badger JD 2nd, Cameron HA, Youle RJ, Roche KW.
J Biol Chem, 2019
doi: 10.1074/jbc.RA118.007245

The intramembrane protease SPP impacts morphology of the endoplasmic reticulum by triggering degradation of morphogenic proteins
Avci D, Malchus NS, Heidasch R, Lorenz H, Richter K, Neßling M, Lemberg MK.
J Biol Chem, 2019
doi: 10.1074/jbc.RA118.005642

A Flat BAR Protein Promotes Actin Polymerization at the Base of Clathrin-Coated Pits
Almeida-Souza L, Frank RAW, García-Nafría J, Colussi A, Gunawardana N, Johnson CM, Yu M, Howard G, Andrews B, Vallis Y, McMahon HT.
Cell, 2018
10.1016/j.cell.2018.05.020

Dopamine Secretion Is Mediated by Sparse Active Zone-like Release Sites
Liu C, Kershberg L, Wang J, Schneeberger S, Kaeser PS.
Cell, 2018
10.1016/j.cell.2018.01.008

Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
Freeman SA, Vega A, Riedl M, Collins RF, Ostrowski PP, Woods EC, Bertozzi CR, Tammi MI, Lidke DS, Johnson P, Mayor S, Jaqaman K, Grinstein S.
Cell, 2018
10.1016/j.cell.2017.12.023

Visualization of Membrane Pore in Live Cells Reveals a Dynamic-Pore Theory Governing Fusion and Endocytosis
Shin W, Ge L, Arpino G, Villarreal SA, Hamid E, Liu H, Zhao WD, Wen PJ, Chiang HC, Wu LG.
Cell, 2018
10.1016/j.cell.2018.02.062

Assessing photodamage in live-cell STED microscopy
Kilian N, Goryaynov A, Lessard MD, Hooker G, Toomre D, Rothman JE, Bewersdorf J.
Nat Methods, 2018
10.1038/s41592-018-0145-5

Quantitative mapping and minimization of super-resolution optical imaging artifacts
Culley S, Albrecht D, Jacobs C, Pereira PM, Leterrier C, Mercer J, Henriques R.
Nat Methods, 2018
10.1038/nmeth.4605

I-motif DNA structures are formed in the nuclei of human cells
Zeraati M, Langley DB, Schofield P, Moye AL, Rouet R, Hughes WE, Bryan TM, Dinger ME, Christ D.
Nat Chem, 2018
10.1038/s41557-018-0046-3

Second signals rescue B cells from activation-induced mitochondrial dysfunction and death
Akkaya M, Traba J, Roesler AS, Miozzo P, Akkaya B, Theall BP, Sohn H, Pena M, Smelkinson M, Kabat J, Dahlstrom E, Dorward DW, Skinner J, Sack MN, Pierce SK.
Nat Immunol, 2018
10.1038/s41590-018-0156-5

Synaptic nanomodules underlie the organization and plasticity of spine synapses
Hruska M, Henderson N, Le Marchand SJ, Jafri H, Dalva MB.
Nat Neurosci, 2018
10.1038/s41593-018-0138-9

Neutralizing Antibodies Inhibit Chikungunya Virus Budding at the Plasma Membrane
Jin J, Galaz-Montoya JG, Sherman MB, Sun SY, Goldsmith CS, O'Toole ET, Ackerman L, Carlson LA, Weaver SC, Chiu W, Simmons G.
Cell Host Microbe, 2018
10.1016/j.chom.2018.07.018

Single HIV-1 Imaging Reveals Progression of Infection through CA-Dependent Steps of Docking at the Nuclear Pore, Uncoating, and Nuclear Transport
Francis AC, Melikyan GB.
Cell Host Microbe, 2018
10.1016/j.chom.2018.03.009

HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and Induces CTCF Clustering across Cell Types
Zirkel A, Nikolic M, Sofiadis K, Mallm JP, Brackley CA, Gothe H, Drechsel O, Becker C, Altmüller J, Josipovic N, Georgomanolis T, Brant L, Franzen J, Koker M, Gusmao EG, Costa IG, Ullrich RT, Wagner W, Roukos V, Nürnberg P, Marenduzzo D, Rippe K, Papantonis A.
Mol Cell, 2018
10.1016/j.molcel.2018.03.030

Separating Actin-Dependent Chemokine Receptor Nanoclustering from Dimerization Indicates a Role for Clustering in CXCR4 Signaling and Function
Martínez-Muñoz L, Rodríguez-Frade JM, Barroso R, Sorzano CÓS, Torreño-Pina JA, Santiago CA, Manzo C, Lucas P, García-Cuesta EM, Gutierrez E, Barrio L, Vargas J, Cascio G, Carrasco YR, Sánchez-Madrid F, García-Parajo MF, Mellado M.
Mol Cell, 2018
10.1016/j.molcel.2018.02.034

Telomere Loop Dynamics in Chromosome End Protection
Van Ly D, Low RRJ, Frölich S, Bartolec TK, Kafer GR, Pickett HA, Gaus K, Cesare AJ.
Mol Cell, 2018
10.1016/j.molcel.2018.06.025

Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA
Nicholls TJ, Nadalutti CA, Motori E, Sommerville EW, Gorman GS, Basu S, Hoberg E, Turnbull DM, Chinnery PF, Larsson NG, Larsson E, Falkenberg M, Taylor RW, Griffith JD, Gustafsson CM.
Mol Cell, 2018
10.1016/j.molcel.2017.11.033

Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies
Dejanovic B, Huntley MA, De Mazière A, Meilandt WJ, Wu T, Srinivasan K, Jiang Z, Gandham V, Friedman BA, Ngu H, Foreman O, Carano RAD, Chih B, Klumperman J, Bakalarski C, Hanson JE, Sheng M.
Neuron, 2018
10.1016/j.neuron.2018.10.014

Differential Nanoscale Topography and Functional Role of GluN2-NMDA Receptor Subtypes at Glutamatergic Synapses
Kellermayer B, Ferreira JS, Dupuis J, Levet F, Grillo-Bosch D, Bard L, Linarès-Loyez J, Bouchet D, Choquet D, Rusakov DA, Bon P, Sibarita JB, Cognet L, Sainlos M, Carvalho AL, Groc L.
Neuron, 2018
10.1016/j.neuron.2018.09.012

Filopodia Conduct Target Selection in Cortical Neurons Using Differences in Signal Kinetics of a Single Kinase
Mao YT, Zhu JX, Hanamura K, Iurilli G, Datta SR, Dalva MB.
Neuron, 2018
10.1016/j.neuron.2018.04.011

Presynaptic Biogenesis Requires Axonal Transport of Lysosome-Related Vesicles
Vukoja A, Rey U, Petzoldt AG, Ott C, Vollweiter D, Quentin C, Puchkov D, Reynolds E, Lehmann M, Hohensee S, Rosa S, Lipowsky R, Sigrist SJ, Haucke V.
Neuron, 2018
10.1016/j.neuron.2018.08.004

RIM C(2)B Domains Target Presynaptic Active Zone Functions to PIP(2)-Containing Membranes
de Jong APH, Roggero CM, Ho MR, Wong MY, Brautigam CA, Rizo J, Kaeser PS.
Neuron, 2018
10.1016/j.neuron.2018.03.011

α-Actinin Anchors PSD-95 at Postsynaptic Sites
Matt L, Kim K, Hergarden AC, Patriarchi T, Malik ZA, Park DK, Chowdhury D, Buonarati OR, Henderson PB, Gökçek Saraç Ç, Zhang Y, Mohapatra D, Horne MC, Ames JB, Hell JW.
Neuron, 2018
10.1016/j.neuron.2018.01.036

Thanatin targets the intermembrane protein complex required for lipopolysaccharide transport in Escherichia coli
Vetterli SU, Zerbe K, Müller M, Urfer M, Mondal M, Wang SY, Moehle K, Zerbe O, Vitale A, Pessi G, Eberl L, Wollscheid B, Robinson JA.
Sci Adv, 2018
10.1126/sciadv.aau2634

A novel atypical sperm centriole is functional during human fertilization
Fishman EL, Jo K, Nguyen QPH, Kong D, Royfman R, Cekic AR, Khanal S, Miller AL, Simerly C, Schatten G, Loncarek J, Mennella V, Avidor-Reiss T.
Nat Commun, 2018
10.1038/s41467-018-04678-8

A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions
Brown JM, Roberts NA, Graham B, Waithe D, Lagerholm C, Telenius JM, De Ornellas S, Oudelaar AM, Scott C, Szczerbal I, Babbs C, Kassouf MT, Hughes JR, Higgs DR, Buckle VJ.
Nat Commun, 2018
10.1038/s41467-018-06248-4

APC2 controls dendrite development by promoting microtubule dynamics
Kahn OI, Schätzle P, van de Willige D, Tas RP, Lindhout FW, Portegies S, Kapitein LC, Hoogenraad CC.
Nat Commun, 2018
10.1038/s41467-018-05124-5

Cell shape-independent FtsZ dynamics in synthetically remodeled bacterial cells
Söderström B, Badrutdinov A, Chan H, Skoglund U.
Nat Commun, 2018
10.1038/s41467-018-06887-7

Ependymal cilia beating induces an actin network to protect centrioles against shear stress
Mahuzier A, Shihavuddin A, Fournier C, Lansade P, Faucourt M, Menezes N, Meunier A, Garfa-Traoré M, Carlier MF, Voituriez R, Genovesio A, Spassky N, Delgehyr N.
Nat Commun, 2018
10.1038/s41467-018-04676-w

Exploiting the tunability of stimulated emission depletion microscopy for super-resolution imaging of nuclear structures
Sarmento MJ, Oneto M, Pelicci S, Pesce L, Scipioni L, Faretta M, Furia L, Dellino GI, Pelicci PG, Bianchini P, Diaspro A, Lanzanò L.
Nat Commun, 2018
10.1038/s41467-018-05963-2

Frustrated endocytosis controls contractility-independent mechanotransduction at clathrin-coated structures
Baschieri F, Dayot S, Elkhatib N, Ly N, Capmany A, Schauer K, Betz T, Vignjevic DM, Poincloux R, Montagnac G.
Nat Commun, 2018
10.1038/s41467-018-06367-y

Local structure in deeply supercooled liquids exhibits growing lengthscales and dynamical correlations
Hallett JE, Turci F, Royall CP.
Nat Commun, 2018
10.1038/s41467-018-05371-6

Microglia innately develop within cerebral organoids
Ormel PR, Vieira de Sá R, van Bodegraven EJ, Karst H, Harschnitz O, Sneeboer MAM, Johansen LE, van Dijk RE, Scheefhals N, Berdenis van Berlekom A, Ribes Martínez E, Kling S, MacGillavry HD, van den Berg LH, Kahn RS, Hol EM, de Witte LD, Pasterkamp RJ.
Nat Commun, 2018
10.1038/s41467-018-06684-2

Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis
Tu HQ, Qin XH, Liu ZB, Song ZQ, Hu HB, Zhang YC, Chang Y, Wu M, Huang Y, Bai YF, Wang G, Han QY, Li AL, Zhou T, Liu F, Zhang XM, Li HY.
Nat Commun, 2018
10.1038/s41467-018-07664-2

Presenilin-mediated cleavage of APP regulates synaptotagmin-7 and presynaptic plasticity
Barthet G, Jordà-Siquier T, Rumi-Masante J, Bernadou F, Müller U, Mulle C.
Nat Commun, 2018
10.1038/s41467-018-06813-x

RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia
Cheng JX, Chen L, Li Y, Cloe A, Yue M, Wei J, Watanabe KA, Shammo JM, Anastasi J, Shen QJ, Larson RA, He C, Le Beau MM, Vardiman JW.
Nat Commun, 2018
10.1038/s41467-018-03513-4

The AFF-1 exoplasmic fusogen is required for endocytic scission and seamless tube elongation
Soulavie F, Hall DH, Sundaram MV.
Nat Commun, 2018
10.1038/s41467-018-04091-1

The mitotic spindle is chiral due to torques within microtubule bundles
Novak M, Polak B, Simunić J, Boban Z, Kuzmić B, Thomae AW, Tolić IM, Pavin N.
Nat Commun, 2018
10.1038/s41467-018-06005-7

Vertebrate myosin 1d regulates left-right organizer morphogenesis and laterality
Saydmohammed M, Yagi H, Calderon M, Clark MJ, Feinstein T, Sun M, Stolz DB, Watkins SC, Amack JD, Lo CW, Tsang M.
Nat Commun, 2018
10.1038/s41467-018-05866-2

A novel long non-coding RNA from NBL2 pericentromeric macrosatellite forms a perinucleolar aggregate structure in colon cancer
Dumbovic G, Biayna J, Banús J, Samuelsson J, Roth A, Diederichs S, Alonso S, Buschbeck M, Perucho M, Forcales SV.
Nucleic Acids Res, 2018
10.1093/nar/gky263

Emerin modulates spatial organization of chromosome territories in cells on softer matrices
Pradhan R, Ranade D, Sengupta K.
Nucleic Acids Res, 2018
10.1093/nar/gky288

Oligomerization of Drosophila Nucleoplasmin-Like Protein is required for its centromere localization
Anselm E, Thomae AW, Jeyaprakash AA, Heun P.
Nucleic Acids Res, 2018
10.1093/nar/gky988

STED-TEM Correlative Microscopy Leveraging Nanodiamonds as Intracellular Dual-Contrast Markers
Prabhakar N, Peurla M, Koho S, Deguchi T, Näreoja T, Chang HC, Rosenholm JM, Hänninen PE.
Small, 2018
10.1002/smll.201701807

Nanoparticles Can Wrap Epithelial Cell Membranes and Relocate Them Across the Epithelial Cell Layer
Urbančič I, Garvas M, Kokot B, Majaron H, Umek P, Cassidy H, Škarabot M, Schneider F, Galiani S, Arsov Z, Koklic T, Matallanas D, Čeh M, Muševič I, Eggeling C, Štrancar J.
Nano Lett, 2018
10.1021/acs.nanolett.8b02291

Whole-Cell, 3D, and Multicolor STED Imaging with Exchangeable Fluorophores
Spahn C, Grimm JB, Lavis LD, Lampe M, Heilemann M.
Nano Lett, 2019
10.1021/acs.nanolett.8b04385

An actin cytoskeletal barrier inhibits lytic granule release from natural killer cells in patients with Chediak-Higashi syndrome
Gil-Krzewska A, Saeed MB, Oszmiana A, Fischer ER, Lagrue K, Gahl WA, Introne WJ, Coligan JE, Davis DM, Krzewski K.
J Allergy Clin Immunol, 2018
10.1016/j.jaci.2017.10.040

Brd4 and P300 Confer Transcriptional Competency during Zygotic Genome Activation
Chan SH, Tang Y, Miao L, Darwich-Codore H, Vejnar CE, Beaudoin JD, Musaev D, Fernandez JP, Benitez MDJ, Bazzini AA, Moreno-Mateos MA, Giraldez AJ.
Dev Cell, 2019
10.1016/j.devcel.2019.05.037

S-Palmitoylation Sorts Membrane Cargo for Anterograde Transport in the Golgi
Ernst AM, Syed SA, Zaki O, Bottanelli F, Zheng H, Hacke M, Xi Z, Rivera-Molina F, Graham M, Rebane AA, Björkholm P, Baddeley D, Toomre D, Pincet F, Rothman JE.
Dev Cell, 2018
10.1016/j.devcel.2018.10.024

Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy
Richter KN, Revelo NH, Seitz KJ, Helm MS, Sarkar D, Saleeb RS, D'Este E, Eberle J, Wagner E, Vogl C, Lazaro DF, Richter F, Coy-Vergara J, Coceano G, Boyden ES, Duncan RR, Hell SW, Lauterbach MA, Lehnart SE, Moser T, Outeiro TF, Rehling P, Schwappach B, Testa I, Zapiec B, Rizzoli SO.
EMBO J, 2018
10.15252/embj.201695709

Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission
Truckenbrodt S, Viplav A, Jähne S, Vogts A, Denker A, Wildhagen H, Fornasiero EF, Rizzoli SO.
EMBO J, 2018
10.15252/embj.201798044

Pool size estimations for dense-core vesicles in mammalian CNS neurons
Persoon CM, Moro A, Nassal JP, Farina M, Broeke JH, Arora S, Dominguez N, van Weering JR, Toonen RF, Verhage M.
EMBO J, 2018
10.15252/embj.201899672

Developmental Upregulation of Ephrin-B1 Silences Sema3C/Neuropilin-1 Signaling during Post-crossing Navigation of Corpus Callosum Axons
Mire E, Hocine M, Bazellières E, Jungas T, Davy A, Chauvet S, Mann F.
Curr Biol, 2018
10.1016/j.cub.2018.04.026

Nanoscale Dynamism of Actin Enables Secretory Function in Cytolytic Cells
Carisey AF, Mace EM, Saeed MB, Davis DM, Orange JS.
Curr Biol, 2018
10.1016/j.cub.2017.12.044

TOM70 Sustains Cell Bioenergetics by Promoting IP3R3-Mediated ER to Mitochondria Ca(2+) Transfer
Filadi R, Leal NS, Schreiner B, Rossi A, Dentoni G, Pinho CM, Wiehager B, Cieri D, Calì T, Pizzo P, Ankarcrona M.
Curr Biol, 2018
10.1016/j.cub.2017.12.047

Catalytic enzymes are active matter
Jee AY, Cho YK, Granick S, Tlusty T.
Proc Natl Acad Sci U S A, 2018
10.1073/pnas.1814180115

Enzyme leaps fuel antichemotaxis
Jee AY, Dutta S, Cho YK, Tlusty T, Granick S.
Proc Natl Acad Sci U S A, 2018
10.1073/pnas.1717844115

Liprin-α3 controls vesicle docking and exocytosis at the active zone of hippocampal synapses
Wong MY, Liu C, Wang SSH, Roquas ACF, Fowler SC, Kaeser PS.
Proc Natl Acad Sci U S A, 2018
10.1073/pnas.1719012115

Molecular model of the mitochondrial genome segregation machinery in Trypanosoma brucei
Hoffmann A, Käser S, Jakob M, Amodeo S, Peitsch C, Týč J, Vaughan S, Zuber B, Schneider A, Ochsenreiter T.
Proc Natl Acad Sci U S A, 2018
10.1073/pnas.1716582115

Confocal super-resolution imaging of the glomerular filtration barrier enabled by tissue expansion
Unnersjö-Jess D, Scott L, Sevilla SZ, Patrakka J, Blom H, Brismar H.
Kidney Int, 2018
10.1016/j.kint.2017.09.019

CXCL12 blockade preferentially regenerates lost podocytes in cortical nephrons by targeting an intrinsic podocyte-progenitor feedback mechanism
Romoli S, Angelotti ML, Antonelli G, Kumar Vr S, Mulay SR, Desai J, Anguiano Gomez L, Thomasova D, Eulberg D, Klussmann S, Melica ME, Conte C, Lombardi D, Lasagni L, Anders HJ, Romagnani P.
Kidney Int, 2018
10.1016/j.kint.2018.08.013

Active and inactive β1 integrins segregate into distinct nanoclusters in focal adhesions
Spiess M, Hernandez-Varas P, Oddone A, Olofsson H, Blom H, Waithe D, Lock JG, Lakadamyali M, Strömblad S.
J Cell Biol, 2018
10.1083/jcb.201707075

Retrograde regulation of mossy fiber axon targeting and terminal maturation via postsynaptic Lnx1
Liu XD, Zhu XN, Halford MM, Xu TL, Henkemeyer M, Xu NJ.
J Cell Biol, 2018
10.1083/jcb.201803105

The inositol 5-phosphatase INPP5K participates in the fine control of ER organization
Dong R, Zhu T, Benedetti L, Gowrishankar S, Deng H, Cai Y, Wang X, Shen K, De Camilli P.
J Cell Biol, 2018
10.1083/jcb.201802125

NeuN-Specific Fluorescent Probe Revealing Neuronal Nuclei Protein and Nuclear Acids Association in Living Neurons under STED Nanoscopy
Tian X, Liu T, Fang B, Wang A, Zhang M, Hussain S, Luo L, Zhang R, Zhang Q, Wu J, Battaglia G, Li L, Zhang Z, Tian Y.
ACS Appl Mater Interfaces, 2018
10.1021/acsami.8b11102

Active Zone Scaffold Protein Ratios Tune Functional Diversity across Brain Synapses
Fulterer A, Andlauer TFM, Ender A, Maglione M, Eyring K, Woitkuhn J, Lehmann M, Matkovic-Rachid T, Geiger JRP, Walter AM, Nagel KI, Sigrist SJ.
Cell Rep, 2018
10.1016/j.celrep.2018.03.126

Plk1/Polo Phosphorylates Sas-4 at the Onset of Mitosis for an Efficient Recruitment of Pericentriolar Material to Centrosomes
Ramani A, Mariappan A, Gottardo M, Mandad S, Urlaub H, Avidor-Reiss T, Riparbelli M, Callaini G, Debec A, Feederle R, Gopalakrishnan J.
Cell Rep, 2018
10.1016/j.celrep.2018.11.102

X10 expansion microscopy enables 25-nm resolution on conventional microscopes
Truckenbrodt S, Maidorn M, Crzan D, Wildhagen H, Kabatas S, Rizzoli SO.
EMBO Rep, 2018
10.15252/embr.201845836

Chronic 2P-STED imaging reveals high turnover of dendritic spines in the hippocampus in vivo
Pfeiffer T, Poll S, Bancelin S, Angibaud J, Inavalli VK, Keppler K, Mittag M, Fuhrmann M, Nägerl UV.
Elife, 2018
10.7554/eLife.34700

Control of endothelial cell polarity and sprouting angiogenesis by non-centrosomal microtubules
Martin M, Veloso A, Wu J, Katrukha EA, Akhmanova A.
Elife, 2018
10.7554/eLife.33864

Inhibition of oxidative stress in cholinergic projection neurons fully rescues aging-associated olfactory circuit degeneration in Drosophila
Hussain A, Pooryasin A, Zhang M, Loschek LF, La Fortezza M, Friedrich AB, Blais CM, Üçpunar HK, Yépez VA, Lehmann M, Gompel N, Gagneur J, Sigrist SJ, Grunwald Kadow IC.
Elife, 2018
10.7554/eLife.32018

Septal secretion of protein A in Staphylococcus aureus requires SecA and lipoteichoic acid synthesis
Yu W, Missiakas D, Schneewind O.
Elife, 2018
10.7554/eLife.34092

TANGO1 builds a machine for collagen export by recruiting and spatially organizing COPII, tethers and membranes
Raote I, Ortega-Bellido M, Santos AJ, Foresti O, Zhang C, Garcia-Parajo MF, Campelo F, Malhotra V.
Elife, 2018
10.7554/eLife.32723

Evidence for Compartmentalized Axonal Mitochondrial Biogenesis: Mitochondrial DNA Replication Increases in Distal Axons As an Early Response to Parkinson's Disease-Relevant Stress
Van Laar VS, Arnold B, Howlett EH, Calderon MJ, St Croix CM, Greenamyre JT, Sanders LH, Berman SB.
J Neurosci, 2018
10.1523/JNEUROSCI.0541-18.2018

The Microtubule-Associated Protein Tau Mediates the Organization of Microtubules and Their Dynamic Exploration of Actin-Rich Lamellipodia and Filopodia of Cortical Growth Cones
Biswas S, Kalil K.
J Neurosci, 2018
10.1523/JNEUROSCI.2281-17.2017

Tropomodulin Isoform-Specific Regulation of Dendrite Development and Synapse Formation
Omotade OF, Rui Y, Lei W, Yu K, Hartzell HC, Fowler VM, Zheng JQ.
J Neurosci, 2018
10.1523/JNEUROSCI.3325-17.2018

Microtubule organization in presynaptic boutons relies on the formin DAAM
Migh E, Götz T, Földi I, Szikora S, Gombos R, Darula Z, Medzihradszky KF, Maléth J, Hegyi P, Sigrist S, Mihály J.
Development, 2018
10.1242/dev.158519

Condensin I protects meiotic cohesin from WAPL-1 mediated removal
Hernandez MR, Davis MB, Jiang J, Brouhard EA, Severson AF, Csankovszki G.
PLoS Genet, 2018
10.1371/journal.pgen.1007382

Dynamics and control of sister kinetochore behavior during the meiotic divisions in Drosophila spermatocytes
Chaurasia S, Lehner CF.
PLoS Genet, 2018
10.1371/journal.pgen.1007372

A Fundamental Role of Myh9 for Neutrophil Migration in Innate Immunity
Zehrer A, Pick R, Salvermoser M, Boda A, Miller M, Stark K, Weckbach LT, Walzog B, Begandt D.
J Immunol, 2018
10.4049/jimmunol.1701400

A Novel Neutralizing Antibody Specific to the DE Loop of VP1 Can Inhibit EV-D68 Infection in Mice
Zheng H, Wang J, Li B, Guo L, Li H, Song J, Yang Z, Li H, Fan H, Huang X, Long H, Cheng C, Chu M, He Z, Yu W, Li J, Gao Y, Ning R, Li N, Yang J, Wu Q, Shi H, Sun M, Liu L.
J Immunol, 2018
10.4049/jimmunol.1800655

Increased Mitochondrial Biogenesis and Reactive Oxygen Species Production Accompany Prolonged CD4(+) T Cell Activation
Akkaya B, Roesler AS, Miozzo P, Theall BP, Al Souz J, Smelkinson MG, Kabat J, Traba J, Sack MN, Brzostowski JA, Pena M, Dorward DW, Pierce SK, Akkaya M.
J Immunol, 2018
10.4049/jimmunol.1800753

Surface Immobilization of Viruses and Nanoparticles Elucidates Early Events in Clathrin-Mediated Endocytosis
Fratini M, Wiegand T, Funaya C, Jiang Z, Shah PNM, Spatz JP, Cavalcanti-Adam EA, Boulant S.
ACS Infect Dis, 2018
10.1021/acsinfecdis.8b00134

CCDC102B functions in centrosome linker assembly and centrosome cohesion
Xia Y, Huang N, Chen Z, Li F, Fan G, Ma D, Chen J, Teng J.
J Cell Sci, 2018
10.1242/jcs.222901

Characterization of the novel mitochondrial genome replication factor MiRF172 in Trypanosoma brucei
Amodeo S, Jakob M, Ochsenreiter T.
J Cell Sci, 2018
10.1242/jcs.211730

Epstein-Barr Virus-Induced Nodules on Viral Replication Compartments Contain RNA Processing Proteins and a Viral Long Noncoding RNA
Park R, Miller G.
J Virol, 2018
10.1128/JVI.01254-18

Human Parvovirus B19 Utilizes Cellular DNA Replication Machinery for Viral DNA Replication
Zou W, Wang Z, Xiong M, Chen AY, Xu P, Ganaie SS, Badawi Y, Kleiboeker S, Nishimune H, Ye SQ, Qiu J.
J Virol, 2018
10.1128/JVI.01881-17

Synthesis and Evaluation of a Mitochondria-Targeting Poly(ADP-ribose) Polymerase-1 Inhibitor
Krainz T, Lamade AM, Du L, Maskrey TS, Calderon MJ, Watkins SC, Epperly MW, Greenberger JS, Bayır H, Wipf P, Clark RSB.
ACS Chem Biol, 2018
10.1021/acschembio.8b00423

Simultaneously Measuring Image Features and Resolution in Live-Cell STED Images
Barentine AES, Schroeder LK, Graff M, Baddeley D, Bewersdorf J.
Biophys J, 2018
10.1016/j.bpj.2018.07.028

Lipid Composition but Not Curvature Is the Determinant Factor for the Low Molecular Mobility Observed on the Membrane of Virus-Like Vesicles
Urbančič I, Brun J, Shrestha D, Waithe D, Eggeling C, Chojnacki J.
Viruses, 2018
10.3390/v10080415

Genetically Targeted Ratiometric and Activated pH Indicator Complexes (TRApHIC) for Receptor Trafficking
Perkins LA, Yan Q, Schmidt BF, Kolodieznyi D, Saurabh S, Larsen MB, Watkins SC, Kremer L, Bruchez MP.
Biochemistry, 2018
10.1021/acs.biochem.7b01135