Organoids and other complex in vitro models (CIVMs) are becoming increasingly important in early drug discovery and translational research, driven by the need for more predictive, human-relevant data…
Waffle freezing provides an HPF-based route to cryo-ET sample preparation. This workflow guide follows the process from grid and carrier assembly to vitrification, cryo-FIB milling, lamella…
Live‑cell imaging of large, complex biological samples often requires large fields of view, sub-cellular resolution, high-sensitivity, and fast acquisition – all while maintaining low illumination…
Dental professionals often ask: “Should I use dental loupes or invest in a microscope?” This article explores the key differences between dental microscopes and dental loupes, focusing on…
Megakaryocytes play a central role in the biology of myeloproliferative neoplasms (MPNs), yet their in vivo proteomic characterization remains a major challenge due to low abundance and disrupted…
The dental surgical microscope has become increasingly important for high-quality and successful dental medicine, particularly in the field of endodontics. A dentist can conduct micro-invasive…
Learn multiscale organoid imaging: fixed high content phenotyping, gentle dual view light sheet, and reproducible pipelines that turn 3D data into insights.
Förster resonance energy transfer (FRET) is a well-established fluorescence-based technique which is used to study molecular interactions. It is useful for the analysis of protein-DNA and…
Many cellular functions depend on the dynamic balance of ions, electric potentials, and pH between the cytosol and surrounding extracellular space. Changes in these values affect cellular function.…
3D digital visualization is rapidly transforming ophthalmic surgery. Modern 3D surgical microscopes enable surgeons to perform procedures using high-resolution digital displays rather than traditional…