THUNDER モデル生物
THUNDER Imaging Systems
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THUNDER モデル生物
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Imaging Organoid Models to Investigate Brain Health
Imaging human brain organoid models to study the phenotypes of specialized brain cells called microglia, and the potential applications of these organoid models in health and disease.
How Microscopy Helps the Study of Mechanoceptive and Synaptic Pathways
In this podcast, Dr Langenhan explains how microscopy helps his team to study mechanoceptive and synaptic pathways, their challenges, and how they overcome them.
Central Nervous System (CNS) Development and Activity in Organisms
This article shows how studying central nervous system (CNS) development in Drosophila-melanogaster embryos expressing a GCaMP calcium indicator in the neurons can be improved with a THUNDER Imager.
Going Beyond Deconvolution
Widefield fluorescence microscopy is often used to visualize structures in life science specimens and obtain useful information. With the use of fluorescent proteins or dyes, discrete specimen…
Find Relevant Specimen Details from Overviews
Switch from searching image by image to seeing the full overview of samples quickly and identifying the important specimen details instantly with confocal microscopy. Use that knowledge to set up…
Accurately Analyze Fluorescent Widefield Images
The specificity of fluorescence microscopy allows researchers to accurately observe and analyze biological processes and structures quickly and easily, even when using thick or large samples. However,…
Optimizing THUNDER Platform for High-Content Slide Scanning
With rising demand for full-tissue imaging and the need for FL signal quantitation in diverse biological specimens, the limits on HC imaging technology are tested, while user trainability and…
Physiology Image Gallery
Physiology is about the processes and functions within a living organism. Research in physiology focuses on the activities and functions of an organism’s organs, tissues, or cells, including the…
Neuroscience Images
Neuroscience commonly uses microscopy to study the nervous system’s function and understand neurodegenerative diseases.
Developmental Biology Image Gallery
Developmental biology explores the development of complex organisms from the embryo to adulthood to understand in detail the origins of disease. This category of the gallery shows images about…
Download The Guide to Live Cell Imaging
In life science research, live cell imaging is an indispensable tool to visualize cells in a state as in vivo as possible. This E-book reviews a wide range of important considerations to take to…
Studying Cell Division
Cell division is a biological process during which all cellular components must be distributed among the daughter cells. The division process requires firm coordination for success. Microscopy is…
The Power of Pairing Adaptive Deconvolution with Computational Clearing
Learn how deconvolution allows you to overcome losses in image resolution and contrast in widefield fluorescence microscopy due to the wave nature of light and the diffraction of light by optical…
Improvement of Imaging Techniques to Understand Organelle Membrane Cell Dynamics
Understanding cell functions in normal and tumorous tissue is a key factor in advancing research of potential treatment strategies and understanding why some treatments might fail. Single-cell…
Image Gallery: THUNDER Imager
To help you answer important scientific questions, THUNDER Imagers eliminate the out-of-focus blur that clouds the view of thick samples when using camera-based fluorescence microscopes. They achieve…
From Organs to Tissues to Cells: Analyzing 3D Specimens with Widefield Microscopy
Obtaining high-quality data and images from thick 3D samples is challenging using traditional widefield microscopy because of the contribution of out-of-focus light. In this webinar, Falco Krüger…
An Introduction to Computational Clearing
Many software packages include background subtraction algorithms to enhance the contrast of features in the image by reducing background noise. The most common methods used to remove background noise…
Computational Clearing - Enhance 3D Specimen Imaging
This webinar is designed to clarify crucial specifications that contribute to THUNDER Imagers' transformative visualization of 3D samples and improvements within a researcher's imaging-related…
THUNDER Imagers: High Performance, Versatility and Ease-of-Use for your Everyday Imaging Workflows
This webinar will showcase the versatility and performance of THUNDER Imagers in many different life science applications: from counting nuclei in retina sections and RNA molecules in cancer tissue…
Alzheimer Plaques: fast Visualization in Thick Sections
More than 60% of all diagnosed cases of dementia are attributed to Alzheimer’s disease. Typical of this disease are histological alterations in the brain tissue. So far, there is no cure for this…
Real Time Images of 3D Specimens with Sharp Contrast Free of Haze
THUNDER Imagers deliver in real time images of 3D specimens with sharp contrast, free of the haze or out-of-focus blur typical of widefield systems. They can even image clearly places deep inside a…
応用分野
生細胞イメージング
視点を単体の顕微鏡コンポーネントから必要なすべての機能を備えた生細胞イメージングソリューションへと移し、ライカ マイクロシステムズは顕微鏡、LAS X イメージングソフトウェア、カメラおよび専用サードパーティコンポーネントを 1 つの完全な生細胞イメージングシステムに統合します。
ゼブラフィッシュを用いた研究
スクリーニング、ソーティング、マニピュレーションおよびイメージングを通じて最良の結果を得るためには、細部や構造を観察して、研究の次の段階に向けて正しい判断を下す必要があります。
優れた光学系と高解像度で定評のあるライカの実体顕微鏡と透過照明スタンドは、世界中の研究者から支持されています。
神経科学研究
神経変性疾患の理解向上に取り組んでいる、もしくは神経系の機能を研究をしていますか？ ライカマイクロシステムズのイメージングソリューションによってブレイクスルーを起こす方法をご覧ください。
研究におけるモデル生物
モデル生物とは、特定の生物学的プロセスを研究するために研究者が使用する生物種です。 モデル生物は、人間と似た遺伝的特徴を持ち、遺伝子学、発生生物学、神経科学などの研究分野で一般的に使用されています。 通常、モデル生物は実験環境での維持や繁殖が容易であること、生殖サイクルが短いこと、または、特定の形質や病気を研究するために突然変異体を生成する能力を持つことで選ばれます。
ウイルス学
ウイルス研究のためのイメージングと試料作製ソリューション
暗視野顕微鏡
暗視野コントラスト法は、生体試料の構造や物質試料の不均一な特徴から生じる光の回折や散乱を利用する方法です。
