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LMD6 & LMD7 Lasermikrodissektions-Systeme

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Laser Microdissection Protocols for Tissue and Cell Isolation - Download free eBook

In this Bio-protocol Selections, we present a collection of open-access, detailed methods papers using LCM to purify and isolate tissues and cells from plants, mouse embryos, cancer cells, neurons,…

Erforschung der Virusreplikaton mit Fluoreszenzmikroskopie

Viren können mit Hilfe verschiedener Mikroskopietechniken untersucht werden. Je nach Vergrößerung und Auflösung des Mikroskops kann die Beobachtung auf Gewebe-, Zell- oder Virionenebene erfolgen.
Single cell datasets

Exploring Subcellular Spatial Phenotypes with SPARCS

Discover spatially resolved CRISPR screening (SPARCS), a platform for microscopy-based genetic screening for spatial subcellular phenotypes at the human genome scale.
[Translate to German:] Multi-tissue array with 4 markers shown including DAPI, NaKATPase, PanCk, and Vimentin.

Räumliche Biologie: Erwägung neuer Wege

Räumliche Biologie: Forschung zu Anordnung und Interaktion von Molekülen, Zellen und Geweben in ihrem nativen räumlichen Kontext
How is microscopy used in spatial biology - Teaserimage

How is Microscopy Used in Spatial Biology? A Microscopy Guide

Different spatial biology methods in microscopy, such as multiplex imaging, are helping to better understand tissue landscapes. Learn more in this microscopy guide.
Automated Laser Microdissection for Proteome Analysis

Precise Spatial Proteomic Information in Tissues

Despite the availability of imaging-based and mass-spectrometry-based methods for spatial proteomics, a key challenge remains connecting images with single-cell-resolution protein abundance…

20 Years of Leica Laser Microdissection

Phenotype-genotype correlations are key for insight. From Eye to Insight is therefore fitting perfectly to Leica Microsystems and in particular to laser microdissection. Laser Microdissection, also…

How to improve your Biomarker Discovery Workflow with Laser Microdissection

Biomarkers can be used as indicators of certain diseases, such as cancer. The tumor microenvironment moved into the spotlight in this concern. It is in close interaction with the tumor itself.…

Improving RNA Analysis with Laser Microdissection

Parkinson’s disease is a progressive neurodegenerative disorder connected with cell death of dopamine-releasing neurons in the brain. Differences in gene expression between individual…

How to improve your Alzheimer Protein Analysis with Laser Microdissection

Brain Research: Collect pure starting material for proteomics - Improve your workflow with Laser Microdissection - Many brain diseases result from protein malfunction, misfolding and agglutination.…

How to improve your DNA Mutation Analysis Workflow with Laser Microdissection

DNA mutations lead to abnormal proteins or missing functional proteins, which can cause cells to multiply uncontrollably and become cancerous. To find and understand the underlying mutation for a…

Workflows & Protocols: How to Isolate Individual Chromosomes with Laser Microdissection

During the first Leica Workshop in Brazil, at the Centro de Energia Nuclear na Agricultura/USP (CENA), the participants learned how to prepare samples for laser microdissection (LMD) using a cryotome.…

Workflows & Protocols: How to Use a Leica Laser Microdissection System and Qiagen Kits for Successful RNA Analysis

Laser Microdissection (LMD) allows isolating individual cells or chromosomes and is a well established technique for sample preparation prior downstream analysis of the nucleic acid content via PCR or…
SPERM HY-LITER™ staining of a sexual assault smear slide which was performed by a forensic DNA crime laboratory.

Forensic Detection of Sperm from Sexual Assault Evidence

The impact of modern scientific methods on the analysis of crime scene evidence has dramatically changed many forensic sub-specialties. Arguably one of the most dramatic examples is the impact of…

Anwendungsbereiche

Forensik

Leica Microsystems bietet ideale Lösungen für jeden dieser Schritte – von der ersten makroskopischen Betrachtung, über mikroskopische Analyse und forensischen Vergleich, bis zur zeitsparenden…

Virologie

Liegt Ihr Forschungsschwerpunkt auf Virusinfektionen und -krankheiten? Erfahren Sie, wie Sie mit Lösungen für Bildgebung und Probenvorbereitung von Leica Microsystems mehr Erkenntnisse in der…
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