Transformative Technologies in Pancreatic Cancer

Transformative Technologies in Pancreatic Cancer: Multi-omic Insights and Organoid Innovation

In recognition of Pancreatic Cancer Awareness Month, join us to explore how cutting-edge technologies are transforming our understanding of pancreatic ductal adenocarcinoma (PDAC), one of the most lethal and therapy-resistant cancers. Dr. Hartland Jackson utilizes integrated spatial proteomics and laser-capture mass spectrometry to map tumor, stroma, and immune interactions, uncovering novel molecular co-dependencies and enhancing patient stratification. Dr. Max Reichert applies organoid models and spatial transcriptomics to reveal hierarchical cell states that drive PDAC’s heterogeneity, metastatic potential, and therapy response. Together, these presentations showcase how advanced spatial imaging and multi-omics technologies are revolutionizing PDAC research, offering new hope for overcoming resistance and improving outcomes in one of the most challenging cancers.

Moderated by: Andrea Radtke, PhD

Featured Talks:

Integrated spatial proteomics of human PDAC uncovers an expanded tumor–immune–stroma spectrum with genomic associations 

Presented by Dr. Hartland Jackson

From Organoids to Insight: Decoding Plasticity and Heterogeneity in Pancreatic Cancer

Presented by Dr. Max Reichert

Learning Objectives:

• Understand how spatial single-cell and multi-omics data outperform genomic and clinical features in predicting patient outcomes in PDAC
• Recognize that distinct tumor cell states in PDAC exhibit variable metastatic potential and therapy sensitivity, and that these states can be dynamically reshaped by treatment 
• Learn how organoid-based models can recapitulate cellular heterogeneity and hierarchical organization in PDAC

A live discussion and Q&A session will follow, giving you the opportunity to engage directly with leading researchers and gain valuable insights to improve cancer diagnosis, guide therapy decisions, and inform prevention strategies. All sessions will be available on demand, allowing flexible access for continued learning and engagement.

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