STELLARIS 5 & STELLARIS 8 Confocal Microscopes Products Home Leica Leica Microsystems

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Confocal Microscope Platforms STELLARIS 5 & STELLARIS 8

  • Live Cell Imaging

    Shifting perspective from single microscope components to a full working live cell imaging solution, Leica Microsystems integrates microscope, LAS X imaging software, cameras, and dedicated…
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  • Super-Resolution

    Leica Microsystems is a pioneer in super-resolution microscopy working closely in collaboration with top scientists in this field. Leica Microsystems is the only supplier of both, widefield and…
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  • Cancer Research

    Cancer is a complex and heterogeneous disease caused by cells deficient in growth regulation. Genetic and epigenetic changes in one or a group of cells disrupt normal function and result in…
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  • Organoids and 3D Cell Culture

    One of the most exciting recent advancements in life science research is the development of 3D cell culture systems, such as organoids, spheroids, or organ-on-a-chip models. A 3D cell culture is an…
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  • Neuroscience

    Are you working towards a better understanding of neurodegenerative diseases or studying the function of the nervous system? See how you can make breakthroughs with imaging solutions from Leica…
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  • Fluorescence Microscopy

    Fluorescence is one of the most commonly used physical phenomena in biological and analytical microscopy for its high sensitivity and high specificity. Fluorescence is a form of luminescence that…
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  • Fluorescence Lifetime Imaging

    Fluorescence lifetime imaging microscopy (FLIM) is an imaging technique that makes use of the inherent properties of fluorescent dyes. Aside from having characteristic emission spectra, each…
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  • Leica Cell Biology

    Cell Biology

    When your research is centered on understanding the cellular basis of human health and disease, it is critical to investigate the cells of interest in spatiotemporal and molecular detail.…
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  • Virology

    Do your research interests focus on viral infection and disease? Find out how you can gain insights into virology with solutions for imaging and sample preparation from Leica Microsystems.
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  • Model Organisms in Research

    A model organism is a species used by researchers to study specific biological processes. They have similar genetic characteristics to humans and are commonly used in research areas such as genetics,…
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  • Confocal imaging of a SARS-CoV-2-infected epithelia at 4 dpi (orthogonal sections)
    Science Lab Topic: Confocal Microscopy

    STELLARIS Contributes to Understanding COVID-19 Infection

    What are the structural and functional consequences of a SARS-CoV-2 infection? To answer this important question, the authors used 3D cultures that mimic an airway epithelium and used different…
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  • AiviaMotion: Truly simultaneous multicolor imaging of live cells (U2OS) in 3D
    Science Lab Topic: Confocal Microscopy

    Artificial Intelligence and Confocal Microscopy – What You Need to Know

    This list of frequently asked questions provides “hands-on” answers and is a supplement to the introductory article about AiviaMotion "How Artificial Intelligence Enhances Confocal Imaging"
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  • Science Lab Topic: Confocal Microscopy

    How Artificial Intelligence Enhances Confocal Imaging

    In this article, we show how artificial intelligence (AI) can enhance your imaging experiments. Namely, how AiviaMotion improves image quality while capturing the temporal dynamics of your live-cell…
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  • Science Lab Topic: Confocal Microscopy

    Spectroscopic Evaluation of Red Blood Cells

    Hemoglobinopathies are a major healthcare problem. This study presents a possible diagnostic tool for thalassemia which is based on confocal spectroscopy. This approach exploits spectral detection and…
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  • Science Lab Topic: Confocal Microscopy

    Visualizing Protein Degradation and Aggregation in the Living Cell

    Our guest speaker, Prof Dr Eric Reits, presents his work on neurodegenerative disorders. Reits’ group are experts on the subject of Huntington’s disease and work towards identifying leads for…
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  • Science Lab Topic: Confocal Microscopy

    Life Beyond the Pixels: Deep Learning Methods for Single Cell Analysis

    Our guest speaker Prof Dr Peter Horvath presents his work on single cell-based large-scale microscopy experiments. This novel targeting approach includes the use of machine learning models and…
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  • Science Lab Topic: Quantitative Imaging

    Phasor FLIM Detects Metabolic Differences

    The maintenance of normal blood glucose levels is defective in diabetes caused by dysfunction of the alpha and beta cells in islets. To understand these regularities, we used multiphoton phasor-FLIM…
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  • Science Lab Topic: Quantitative Imaging

    Adding Dimensions to Multiplex Molecular Imaging

    Molecular imaging of living specimens offers a means to draw upon the growing body of high-throughput molecular data to better understand the underlying cellular and molecular mechanisms of complex…
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  • Science Lab Topic: Super-Resolution

    Benefits of TauContrast to Image Complex Samples

    In this interview, Dr. Timo Zimmermann talks about his experience with the application of TauSense tools and their potential for the investigation of demanding samples such as thick samples or…
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  • Science Lab Topic: Confocal Microscopy

    A New World of Confocal Applications with the Next Generation White Light Lasers

    As biological questions get more complex, there is an increasing need to study multiple events simultaneously in the same specimen. When preparing the specimen for imaging experiments, this need is…
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  • Science Lab Topic: Confocal Microscopy

    Advanced Quantitative Fluorescence Microscopy to Probe the Molecular Dynamics of Viral Entry

    Viral entry into the host cell requires the coordination of many cellular and viral proteins in a precise order. Modern microscopy techniques are now allowing researchers to investigate these…
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  • Image courtesy of Dr. Stefan Finke, Friedrich-Loeffler- Institute, Riems, Germany.
    Science Lab Topic: THUNDER Imaging

    How Can Immunofluorescence Aid Virology Research?

    Modern virology research has become as crucial now as ever before due to the global COVID-19 pandemic. There are many powerful technologies and assays that virologists can apply to their research into…
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  • Science Lab Topic: Super-Resolution

    Time-resolved STED microscopy

    Introduced more than 30 years ago, stimulated emission depletion (STED) microscopy has raised to a standard and widely used method for imaging in the life sciences. Thanks to continuous technological…
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  • Science Lab Topic: Confocal Microscopy

    Obtain maximum information from your specimen with LIGHTNING

    LIGHTNING is an adaptive process for extraction of information that reveals fine structures and details, otherwise simply not visible, fully automatically. Unlike traditional technologies, that use a…
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  • Science Lab Topic: Confocal Microscopy

    Infection of the novel coronavirus SARS-CoV-2 can be blocked by a human monoclonal antibody

    Vaccines and targeted therapeutics for treatment of the respiratory disease COVID-19, caused by the coronavirus SARS-CoV-2, are currently lacking. Based on the results of this study, it was reported…
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  • Science Lab Topic: Confocal Microscopy

    Expanding the frontiers of confocal live cell imaging

    To address the specific challenges of live cell confocal imaging and help researchers get closer to the truth, Leica Microsystems has re-imagined confocal microscopy, designing its entirely new…
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  • Science Lab Topic: Confocal Microscopy

    Nanoscopy meets Lifetime: Introducing TauSTED

    τ-STED combines the optical signals from STED and the photophysical information from the fluorescence lifetime at unprecedented speeds. This approach to STED uses phasor analysis in a novel way.…
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  • Science Lab Topic: Confocal Microscopy

    Explore Innovative Techniques to Separate Fluorophores with Overlapping Spectra

    In this article we explore several strategies you can take to improve the separation of fluorophores and increase the number of fluorescent probes you can distinguish in your sample.
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  • Science Lab Topic: Confocal Microscopy

    STELLARIS White light lasers

    When it comes to choosing fluorescent probes for your multi-color experiments, you shouldn’t have to compromise. Now you can advance beyond conventional excitation sources that limit your fluorophore…
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  • Science Lab Topic: Confocal Microscopy

    TauSense Technolgy Imaging Tools

    Leica Microsystems’ TauSense technology is a set of imaging modes based on fluorescence lifetime. Found at the core of the STELLARIS confocal platform, it will revolutionize your imaging experiments.…
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  • Science Lab Topic: Confocal Microscopy

    The Power HyD detector family

    In STELLARIS, we have pushed the limits of our detector technology, so you can push the boundaries of your research. Our newly designed Power HyD family consists of three different type of detectors…
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  • Science Lab Topic: Confocal Microscopy

    How to Uncover Hidden Dimensions in Research with Lifetime Imaging

    Learn how fluorescence lifetime imaging adds information depth to your confocal experiments and reveals novel insights that are difficult or impossible to discover using conventional intensity-based…
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  • Science Lab Topic: Confocal Microscopy

    Learn how to Remove Autofluorescence from your Confocal Images

    Autofluorescence can significantly reduce what you can see in a confocal experiment. This article explores causes of autofluorescence as well as different ways to remove it, from simple media fixes to…
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  • Science Lab Topic: Quantitative Imaging

    What is FLIM - Fluorescence Lifetime Imaging?

    The fluorescence lifetime is a measure of how long a fluorophore remains on average in its excited state before returning to the ground state by emitting a fluorescence photon.
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  • Science Lab Topic: Neuroscience

    Neurobiology and Microscopy

    Neurobiology, the science of nerves and the brain, has mainly been driven forward in the last 200 years by microscopic investigations. The structures of cellular and subcellular structures,…
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