
See the Hidden
DMi8 S module Infinity TIRF
Observe samples with outstanding clarity, control, and confidence with DMi8 S and Infinity TIRF. For dynamic processes at the cell surface, TIRF (Total Internal Reflection Fluorescence) microscopy is the method of choice to visualize single molecules with super-resolution by maximizing the fluorescent signal-to-noise ratio.
The Infinity TIRF module delivers versatile application possibilities with simultaneous multi-color EPI, Hi-Lo and TIRF illumination capability, as well as a high power illumination option for super-resolution applications.
Reveal the missing links in your cells.
Focus on the cell
Take the mystery out of setting up a TIRF experiment with the fully automated Infinity TIRF.
Sample-specific alignment and calibration via integrated sensors ensure that your results are consistent and reproducible.
Integration with LAS X
Full integration with LAS X software helps you minimize setup and training time so that you can get to what really matters: your experiment.

2 TIRF Scanner: Fine-tuning of TIRF penetration depth and adjustment of illumination direction (azimuth)
3 Movable collimator: Allows TIRF over full z-travel range with all Leica TIRF objectives
4 Merge Optics: Combines a second illumination light path through Infinity TIRF module
5 Beam Expander: Infinity TIRF HP module increases the power density on the sample for super-resolution imaging

Plan APO TIRF objectives
High image quality starts with brilliant optics. With Plan APO corrected TIRF objectives and Field Number 19, you can see the smallest details of your sample, even at the edges of the field.
The PLAN APO TIRF objectives from Leica Microsystems offer you the largest field of view on the market.
See more with these dedicated TIRF objectives.
Life in colors
The Infinity TIRF can be used with the wide range of available widefield lasers, so you can see the entire spectrum of fluorescence.
Get the whole story of dynamic live processes in your cells with simultaneous multiple-color imaging.
Lasers available
- 1-5 laser lines
- 405-640nm
- 60-150mW
Find the best angle
Every samples is unique and our technology is designed to work with distinct samples.
Look at cells from every angle to find the best imaging conditions.
The Infinity TIRF module includes azimuth shifting capability so that you can find the perfect image of your sample every time.
Super-resolution
Supercharge your system with super-resolution and nanoscopy capabilities. Choose the Infinity TIRF High Power (HP) system to give you the ability to achieve multi-color single molecule resolution at the cell surface to resolve structures involved in receptor trafficking, synaptic organization, or cell adhesion.
With the high-powered lasers option, you can image and analyze down to 20nm resolution with techniques such as single molecule particle tracking, GSD, dSTORM and uPaint.
Multimodal widefield imaging system
Create a multimodal widefield imaging system by combining the Infinity Scanner and Infinity TIRF with the DMi8 inverted microscope system to expand your research capabilities.
Combine applications like TIRF, FRAP, photoswitching, ablation, optogenetics and many more to reveal more details in your dynamic molecular processes than ever before.
Expand your application flexibility even more by adding the Infinity TIRF module to the SP8 confocal system.
Interested to know more?
Talk to our experts. We are happy to answer all your questions and concerns.
Contact UsDo you prefer personal consulting?
-
Leica Microsystems Inc.1700 Leider LaneBuffalo Grove, IL 60089 United StatesOffice Phone : +1 800 248 0123Service Phone : 1 800 248 0223Fax : +1 847-236-3009
-
JH Technologies, Inc.213 Hammond AvenueFremont, 94539 United StatesOffice Phone : 408-436-6336Fax : 408-436-6343
-
Precision Lens5715 West Old Shakopee Road Unit 150Bloomington, 55437 United StatesOffice Phone : 952-881-0414
-
D.M.I. Medical Inc.Life Science Research: Confocal Microscopy, Widefield, Nanotechnology, Industry Microscopy, Clinical Microscopy, Surgical Microscopy, Digital Pathology, Cytovision, Aperio, Ariol, Histology Instruments, Histology Consumables, Advanced Staining Instruments, Advanced Staining Consumables, Kreatech Reagents, Thermobrite / Thermobrite Elite4611 S. University Dr. Suite 435Davie, 33328 United StatesOffice Phone : +1-954-538-3808Service Phone : +1-954-328-0693Fax : +1-866-492-6373
-
D.M.I. Medical IncHistology Systems, Novocastra Reagents and associated instruments, EM Sample Preparation4611 S. University Dr. Suite 435Davie, 33328 United StatesOffice Phone : +1-954-538-3808Service Phone : +1-954-328-0693Fax : +1-866-492-6373
-
ECLIPSE SURGICAL SUPPLY LLC616 FAIRWAY MIST CTMINT HILL, 28227 United StatesOffice Phone : 410-299-2711
-
Great Plains Surgical, Inc.3605 Hidden CircleWest Fargo, 58078 United StatesOffice Phone : 701-391-3333Service Phone : 701-391-3333Fax : 701-364-0307
-
ICMAS Inc.120 McCammon AveMaryville, 37804 United StatesOffice Phone : 865-984-8058
-
Integrity Surgical2303 Ranch Road 620 S Suite 160-310Lakeway, 78734 United StatesOffice Phone : 713-201-8787
-
Next Case Surgical943 Maple Avenue - Upper LevelDowners Grove, 60515 United StatesOffice Phone : 312-520-7600Fax : 219-662-7353
-
Proficient Surgical Equipment, Inc99 Seaview Blvd. Suite CPort Washington, 11050 United StatesOffice Phone : 516-487-1175Fax : 516-487-1191
-
JH Technologies, Inc. - Neast213 Hammond AveFremont, 94539 United StatesOffice Phone : 408-436-6336Fax : 408-436-6343
-
JH Technologies So. Cal213 Hammond AveFremont, 94539 United StatesOffice Phone : 408-436-6336Fax : 408-439-6343
-
Q Surgical28 Liberty Ship Way Suite 2830Sausalito, 94965 United StatesOffice Phone : 415-331-1020Fax : 415-462-5186
-
Rohlf Medical, Inc.2600 S. Minnesota Ave Suite 101Sioux Falls, 57105 United StatesOffice Phone : 605-334-8655Fax : 605-334-9102
-
Shawnee Medical Products, Inc.8401 Juniper LanePrairie Village, 66207 United StatesOffice Phone : 913-341-7520Fax : 913-341-2318
-
Spective, LLC3103 Glenwood DriveDurham, 27705 United StatesOffice Phone : 9194526288
-
Spective LLC - Canada3103 Glenwood DriveDurham, 27705 United StatesOffice Phone : 9194526288
-
SurgicalOne, Inc.23030 E Industrial DriveSAINT CLAIR SHORES, 48080 United StatesOffice Phone : 586-775-3300Fax : 586-775-3301
-
TAP Medical Products, Inc.4580 Klahanie Drive S.E. #452Issaquah, 98029 United StatesOffice Phone : 425-785-9993Fax : 800-832-1859
-
Western Microsurgical6721 Esperanza DriveCastle Rock, 80108 United StatesOffice Phone : 720-244-4679Fax : 303-331-8128
-
NCI, Inc.7125 Northland Terrace N. Suite 100Brooklyn Park, 55428 United StatesOffice Phone : 763-559-3008Fax : 763-559-7372
-
NCI, Inc.7125 Northland Terrace N. Suite 100Brooklyn Park, 55428 United StatesOffice Phone : 763-559-3008Fax : 763-559-7372
-
W. Nuhsbaum Inc.760 Ridgeview DriveMcHenry, 60050 United StatesOffice Phone : 815-385-5200Fax : 815-385-5236
-
Angstrom Scientific Inc.120 N CENTRAL AVE STE 3Ramsey, 07446 United StatesOffice Phone : 2019627222Fax : 2019628290
-
Associated Microscope Inc.412 Holly Hill LnBurlington, 27215 United StatesOffice Phone : 336-538-1842Fax : 336-538-1847
-
I. Miller Precision Optical Instruments Inc.325 Bustleton PikeFeasterville Trevose, 19053 United StatesOffice Phone : 215-925-2285Fax : 215-925-8374
-
Marathon Medical, Inc.1408 Christian Avenue Suite 35Durham, 27705 United StatesOffice Phone : 919-309-4463Service Phone : 919-812-9500Fax : 919-309-4742
-
DB Surgical12480 West Atlantic Blvd Suite 1Coral Springs, 33071 United StatesOffice Phone : 954-340-2727Fax : 954-340-1221