Spectroscopic Evaluation of Red Blood Cells

 Spectroscopic_Evaluation_of_Red_Blood_Cells_teaser.jpg

Hemoglobinopathies are a major healthcare problem. This study presents a possible diagnostic tool for thalassemia which is based on confocal spectroscopy. This approach exploits spectral detection and white light laser excitation to acquire autofluorescence signals from red blood cells (RBCs).

The discrimination between healthy and diseased RBCs was performed with autofluorescence signals using 405 nm excitation and acquiring the emission from 425 nm to 790 nm. Three characteristics were calculated from the mean emission intensities at 502 nm, 579 nm, 628 nm, and 649 nm.

From the results shown in this study, spectral confocal microscopy could be a useful tool for the discrimination of healthy and thalassemia patients.

Read the full article:

Rey-Barroso L., Roldán M., Burgos-Fernández F.J., Gassiot S., Ruiz Llobet A., Isola I. & Vilaseca M..:

Spectroscopic Evaluation of Red Blood Cells of Thalassemia Patients with Confocal Microscopy: A Pilot Study

Sensors 2020, 20(14), 4039; https://doi.org/10.3390/s20144039

Interested to know more?

Talk to our experts. We are happy to answer all your questions and concerns.

Contact Us

Do you prefer personal consulting?

  • Leica Microsystems Inc.
    1700 Leider Lane
    Buffalo Grove, IL 60089 United States
    Office Phone : +1 800 248 0123
    Service Phone : 1 800 248 0223
    Fax : +1 847-236-3009

You will find a more detailed list of local contacts here.