Webinar

Understanding Motor Sequence Generation Across Spatiotemporal Scales

Motor sequences are important elements of everyday behavior, but how they are produced by central neural circuits is poorly understood. The fruit fly exhibits complex behaviors and lends itself to genetic manipulation and imaging techniques that can be used to study neural circuits underlying behavior. We have developed a microscopy-based pipeline to characterize a developmentally critical behavior at the pupal stage of development, called the ecdysis sequence. We study brain-wide neuronal activity with a custom light-sheet microscope, whole-organism behavior at single muscle-fiber resolution and bridge the gap with simultaneous dual-color imaging of muscle activity with sensory neuron or motor neuron activity. These tools allow us to determine the roles of specific populations of neurons in generating motor output.

Authors

Topics & Tags

Learning Objectives:

  • Relevant biological scales for studying motor generation
  • Advantages of Drosophila in neurobiology
  • Microscopy techniques for multi-scale imaging

Register to watch the Video

*
*
*
*
*
*
By clicking on the SUBMIT button, I confirm that I have reviewed and agree with Leica Microsystems GmbH Terms of Use and their Privacy Policy. I also understand my privacy choices as they pertain to my personal data, as detailed in the aforementioned Privacy Policy under ‘’Your Privacy Choices’’.

Interested to know more?

Talk to our experts. We are happy to answer all your questions and concerns.

Contact Us

Do you prefer personal consulting?

  • Leica Microsystems Inc.
    1700 Leider Lane
    Buffalo Grove, IL 60089 United States
    Office Phone : +1 800 248 0123
    Service Phone : 1 800 248 0223
    Fax : +1 847-236-3009

You will find a more detailed list of local contacts here.