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Coherent Raman Scattering Microscope STELLARIS 8 CRS

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  • Multi-color SRS image of tri-cellular cancer spheroid showing total lipids (yellow, 2850 cm-1), unsaturated lipids (magenta, 3050 cm-1), collagen (SHG, cyan). Sample courtesy of R. Rudolf, J Klicks, Hochschule Mannheim

    The Potential of Coherent Raman Scattering Microscopy at a Glance

    Coherent Raman scattering microscopy (CRS) is a powerful approach for label-free, chemically specific imaging. It is based on the characteristic intrinsic vibrational contrast of molecules in the…
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  • Formulated Product Characterization with SRS Microscopy

    Creams, pastes, gels, emulsions, and tablets are ubiquitous across a wide range of manufacturing sectors from pharmaceuticals and consumer health products to agrochemicals and paint. To improve…
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  • Two-color SRS image of human pancreatic organoids showing proteins (red) and lipids (green).

    Vibrational Spectroscopic Imaging in Cells, Tissues and Model Organisms

    Here we present a webinar on the emerging applications of Stimulated Raman Scattering Microscopy, covering the following topics: Quantitative spectroscopic imaging of label-free or chemically tagged…
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  • Step by Step Guide to the Molecular Basics of CARS Microscopy

    CARS (Coherent Anti-Stokes Raman Scattering) microscopy is a dye-free method which images structures by displaying the characteristic intrinsic vibrational contrast of their molecules. The crucial…
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  • Stimulated Raman Scattering Microscopy Probes Neurodegenerative Disease

    Despite decades of research, the molecular mechanisms underlying some of the most severe neurodegenerative diseases, such as Alzheimer’s or Parkinson’s, remain poorly understood. The progression of…
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  • Coherent Raman Scattering (CRS) Microscopy: A vast and growing range of applications revealed

    Leica Microsystems‘ Workshop on Coherent Raman Scattering (CRS) Microscopy attracted 30 enthusiastic participants from all over the world to beautiful Konstanz, Germany! The group enjoyed a number of…
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  • Unmask the Hidden without Probes: CARS

    Fluorescence microscopy assumed a pivotal role in cell biology once it was possible to stain cell components selectively by fluorescing dyes. One of the first explorers of targeted stainings, Paul…
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  • CARS Microscopy: Imaging Characteristic Vibrational Contrast of Molecules

    Coherent anti-Stokes Raman scattering (CARS) microscopy is a technique that generates images based on the vibrational signatures of molecules. This imaging methods does not require labeling, yet…
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  • Fields of Application

  • This confocal image shows one scan layer of the acoel worm Isodiametra pulchra. The following parts are stained: cyan: nuclei, green: stem cells, magenta: expression of the genes T-Brain/Eomes (gonads und oocytes). Left: anterior. The worm is about 1 mm of size. Photo: Aina Børve, Sars

    Live Cell Imaging

    Shifting perspective from single microscope components to a full working live cell imaging solution, Leica Microsystems integrates microscope, LAS X imaging software, cameras, and dedicated…
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  • Cell Culture

    Growing cells under lab conditions is the base for scientists working in fields of cell or developmental biology, cancer research, or any kind of life science and pharma research. Find out how Leica…
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  • Cancer Research

    Cancer is a complex and heterogeneous disease caused by cells deficient in growth regulation. Genetic and epigenetic changes in one or a group of cells disrupt normal function and result in…
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  • Neuroscience

    Are you working towards a better understanding of neurodegenerative diseases or studying the function of the nervous system? See how you can make breakthroughs with imaging solutions from Leica…
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  • Model Organisms in Research

    A model organism is a species used by researchers to study specific biological processes. They have similar genetic characteristics to humans and are commonly used in research areas such as genetics,…
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