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THUNDER Imager Model Organsim with 1x Plan APO objective, zoom factor 11:1, 18 z-slice stack, circa 300 um z-depth. Green (kdrl:GFP) shows angiogenisis and red (GATA1:dsRed) shows red blood cells and platelets.
Image courtesy: Dr. Almary Guerra & Dr. Didier Stainier, Max Planck Institute for Heart and Lung Research, Bad Nauheim (Germany)

Blur-free images with fine details

Get the most information from your precious model organisms and access stunning details. Take advantage of the leap forward in image quality with THUNDER Imager Model Organism compared to conventional stereo microscopes. Thanks to THUNDER, non-relevant background is removed and interesting details are preserved.

Obtain results faster and with higher significance for applications like:

  • Characterization of model organism transgenic lines
  • Detailed observation of model organisms in real time
  • Investigating development of neuronal networks

Image large model organisms under excellent physiological conditions

Have the best of both worlds: THUNDER Imager Model Organism combines a large field of view with high image quality for thick samples that was, so far, only possible with optical sectioning methods. This powerful combination allows you to observe large specimens live under excellent physiological conditions. No need to sedate your organisms.

Gain more insights for a better understanding of the phenomena under investigation. Z-scans through the entire volume of a fish are possible thanks to the excellent optics and removal of out-of-focus signals. Get fast results as just one image per z-plane is required.

With THUNDER Imager Model Organism, you can observe the relevant details in the proper context with a large field of view. With instant Computational Clearing, you can acquire fast z-stack images and use highly sensitive cameras for detection under physiological conditions.

Interactive Image: In this E12-14 mouse (wt sample), neurofilaments are stained in red to assess neuronal outgrowth. The mouse was cleared with the ScaleS reagent. Sample courtesy Yves Lutz, Centre d’imagerie, IGBMC (France).

Mouse
Mouse with THUNDER Imager Model Organism

Explore new terrain

The THUNDER Imager Model Organism helps to simplify the screening and documentation of live model organisms for specific details. Live, moving organisms can be imaged directly in petri dishes or multiwell plates. With the optional 2x corr objective, you can observe specimens in water with sharp focus. There is no need to extract or cut the specimen into sections. Just obtain the relevant data directly.

Time-lapse studies of model organisms are important for looking at development, movement, and reaction. With THUNDER, you obtain images with highly resolved details at the speed of your camera, in real time.

THUNDER Imager for deep insights

Take advantage of the large working distances typical for stereo microscopes. THUNDER Imager Model Organism can make z-stack images, which was not possible before. Look at large organoids and cleared or uncleared mouse organs directly in the petri dish. Your results will be highly valuable and simply impressive.

Interactive Image: An organoid approximately 150 µm in diameter mounted onto a depression slide. Imaged with a stereo microscope using a high resolution objective (FluoCombi III) [left] and a THUNDER Imager Model Organism (right). The THUNDER Imager system delivers a sharper image with higher resolution.

Z-stack of Organoid
Z-stack of Organoid with THUNDER Imager Model Organism

3 Dedicated Configurations

The THUNDER Imager Model Organism are available in 3 dedicated configurations:

  1. Optimized for large fields of view. It is equipped with a 20 megapixel digital camera and a THUNDER 3D station for maximal image processing capabilities.
  2. Optimized to capture even the faintest signals. It is equipped with a state-of-the-art sCMOS, B&W camera, and a THUNDER 3D station for maximal processing capabilities.
  3. Optimized for investigating fast intracellular processes and capable of Instant Computational Clearing (ICC). It is equipped with a state-of-the-art sCMOS camera.