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San Francisco Innovation Hub

Our San Francisco Innovation Hub offers researchers from academia and industry access to state-of-the-art microscopy systems and support to unlock new discoveries. Our systems support the imaging needs of advanced research and provide the technical precision required to visualize dynamic events. Leica experts are on-site to empower researchers to harness data from these advanced imaging systems in order to achieve groundbreaking insights.

Experience the right imaging solutions for your applications at the San Francisco Innovation Hub.

 

Our Systems

STELLARIS 8

STELLARIS 8 is a forward-looking system, offering all the benefits of the STELLARIS 5 core system plus added functionality thanks to an extended spectrum WLL and specialized detector options of the Power HyD family. This allows you to expand the range of confocal applications in your research. STELLARIS 8 can be combined with all Leica Microsystems modalities, including FAst Lifetime CONtrast (FALCON), Deep In Vivo Explorer (DIVE), STED, Digital Light Sheet (DLS) and CARS. STELLARIS 8 new features maximize the potential of these modalities and give you the power and potential to set new standards for research.

In our office the Stellaris 8 is equipped with the following:

  • White Light Laser with tunability from the 440-790nm range
  • Pulse Picker for observing longer lifetimes
  • TauSense Tools
  • FALCON (Fast Lifetime CONtrast)
  • Okolab Cage incubation for live cell imaging
  • Resonance scanner for fast XY scanning
  • SuperZ Galvo for fast Z scanning

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STELLARIS 5 White Light Laser

STELLARIS 5 with White Light Laser is a workhorse confocal with the power to see more in your samples. Our White Light Laser is tunable with single nanometer precision, allowing you to excite your fluorophores more efficiently. Paired with our state-of-the-art HyDS detectors, you can detect out to the Near Infrared range, giving you more flexibility with fluorophore choice. With our white light laser you also can take advantage of our tau tools which put the power of fluorescent lifetime at your fingertips with our easy-to-use interface.

In our office, the Stellaris 5 is equipped with the following:

  • White Light Laser with tunability from the 485-790nm range
  • TauSense tools
  • Resonance scanner for fast XY scanning
  • SuperZ Galvo for fast Z scanning
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MICA

More than a highly automated microscope, Mica unites widefield and confocal imaging in a sample protecting, incubating environment. With the simple push of a button, you have everything you need - all in one place - to supercharge fluorescence imaging workflows and get meaningful scientific results faster.

In our office, the MICA is equipped with the following:

  • Widefield with Thunder computational clearing
  • Point scanning confocal
  • Incubation

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THUNDER Imager Live Cell and 3D Assay

With THUNDER Imagers you begin every experiment with confidence. They are your solution for advanced 3D cell culture assays, whether you want to study stem cells, spheroids, or organoids.

THUNDER Imagers feature the innovative Leica technology Computational Clearing. It efficiently removes out-of-focus blur in real time, enabling the meaningful use of 3D specimens with camera-based fluorescence microscopes. The high sensitivity of the system ensures low phototoxicity and photobleaching, i.e., higher throughput with optimal conditions.

In our office, the Thunder Live Cell is equipped with the following:

  • K8 Camera
  • K3C color camera for RGB/histology imaging
  • Fast and precise quantum stage for high throughput experiments
  • Okolab Stagetop incubation for live cell imaging
  • Led8 – fast switching 8 line LED light source
  • Thunder computational clearing

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Leica M165 FC Fluorescent Stereo Microscope

The Leica M165 FC fully apochromatic corrected stereo microscope with 16.5:1 zoom optics resolves structures down to 1.1 micron for detailed fluorescent imaging.

Image coding allows easy, convenient reproduction of image settings and parameters for fast, consistent, high quality observation and documentation.

TripleBeam technology dedicates a separate beam channel for fluorescence illumination to enhance image contrast, details and intensity for better performance.

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AIVIA

Using state-of-the-art, AI-first software architecture, Aivia is a uniquely innovative and complete 2-to-5D image visualization, analysis and interpretation platform designed for the reliable processing and reconstruction of highly complex images in just minutes.

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Mateo TL

Mateo TL enables all lab members to check and document cell growth status conveniently and comfortably. It makes the process of cell culture checks effortless for every team member, with intuitive setup and use. It improves reproducibility for your experiments through objective confluency evaluation across individuals or experiments.

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TEAM

Leslie Koyama
Advanced Workflow Specialist, Confocal/Leica Imaging Center Lead

Seung-Yi Lee
Advanced Workflow Specialist – Widefield for Northern California and Hawaii

Jeremy Carver
Sr. Account Manager - Bay Area Peninsula, Stanford and UCSC

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