Leica Microsystems

Leica Microsystems

Leica Microsystems ist ein weltweit führender Hersteller von Mikroskopen und wissenschaftlichen Instrumenten. Im 19. Jahrhundert als Familienunternehmen gegründet, war die Geschichte des Unternehmens auf dem Weg zum Weltkonzern von beispielloser Innovation geprägt.

Die traditionell enge Zusammenarbeit mit der Wissenschaft ist der Schlüssel zur Innovationstradition von Leica Microsystems, die auf die Ideen der Anwender zurückgreift und auf deren Bedürfnisse zugeschnittene Lösungen schafft. Auf globaler Ebene ist Leica Microsystems in drei Divisionen gegliedert, die alle zu den führenden Anbietern in ihrem jeweiligen Bereich gehören: Life Science, Industrie und Medizin.

Das Unternehmen ist in über 100 Ländern mit 6 Produktionsstandorten in 5 Ländern, Vertriebs- und Serviceorganisationen in 20 Ländern und einem internationalen Händlernetz vertreten. Der Hauptsitz des Unternehmens liegt in Wetzlar, Deutschland.

https://www.leica-microsystems.com/de

Applying AI and Machine Learning in Microscopy and Image Analysis

Prof. Emma Lundberg is a professor in cell biology proteomics at KTH Royal Institute of Technology, Sweden. She is also the director of the Cell Atlas, an integral part of the Swedish-based Human…

The AI-Powered Pixel Classifier

Achieving reproducible results manually requires expertise and is tedious work. But now there is a way to overcome these challenges by speeding up this analysis to extract the real value of the image…
Image: Adult rat brain. Neurons (Alexa Fluor488, green), Astrocytes (GFAP, red), Nuclei (DAPI, blue). Image courtesy of Prof. En Xu, Institute of Neurosciences and Department of Neurology of the Second Affiliated Hospital of Guangzhou Medical University, China.

Multicolor Microscopy: The Importance of Multiplexing

The term multiplexing refers to the use of multiple fluorescent dyes to examine various elements within a sample. Multiplexing allows related components and processes to be observed in parallel,…

Considerations for Multiplex Live Cell Imaging

Simultaneous multicolor imaging for successful experiments: Live-cell imaging experiments are key to understand dynamic processes. They allow us to visually record cells in their living state, without…

A New Method for Convenient and Efficient Multicolor Imaging

The technique combining hyperspectral unmixing and phasor analysis was developed to simplify the process of getting images from a sample labeled with multiple fluorophores. This aggregate method…
3D-volume-rendered light-sheet microscope image of a spheroid showing depth coding in different colors.

Imaging of Anti-Cancer Drug Uptake in Spheroids using DLS

Spheroid 3D cell culture models mimic the physiology and functions of living tissues making them a useful tool to study tumor morphology and screen anti-cancer drugs. The drug AZD2014 is a recognized…
Wafer

How to Boost your Microelectronic Component Inspection Performance

Do you need to see more when inspecting silicon wafers or MEMS? Would you like to get sharp and detailed sample images which are similar to those from electron microscopes? Watch this free webinar…
Sport Fabrics Taped I3 10x Color

How Industrial Applications Benefit from Fluorescence Microscopy

Watch this free webinar to know more about what you can do with fluorescence microscopy for industrial applications. We will cover a wide range of investigations where fluorescence contrast offers new…

So finden Sie das richtige Mikroskop für Katarakt OPs

Vor der Auswahl eines Augenmikroskops für Kataraktoperationen und andere Eingriffe am vorderen Augenabschnitt ist es sinnvoll, sich mit der Einrichtung der Praxis oder Klinik sowie den jeweiligen…
Spontaneous colon adenoma

Intravital Microscopy of Cancer

Join our guest speaker Prof Dr Jacco van Rheenen, as he presents his work on the identity, behavior and fate of cells that drive the initiation and progression of cancer.
Aivia_Neuroscience-VBE comparison mouse-1_traced_ROI

Accelerating Neuron Image Analysis with Automation

The ability to examine complex neural processes relies on the accurate reconstruction of neuronal networks at scale. Most data extraction methods in neuroscience research are time-consuming and…
Separation of cells based on their tracking status: A colourised binary mask of a time-lapse microscopy field of view of medium confluency with individual cells highlighted as survivors if they can be tracked since the initial movie frame (cyan), incomers if they migrated into the field of view throughout the movie (yellow) or mistracks if an error occurred in the automated trajectory reconstruction (red).

Tracking Single Cells Using Deep Learning

AI-based solutions continue to gain ground in the field of microscopy. From automated object classification to virtual staining, machine and deep learning technologies are powering scientific…
Mikroskop für Routineuntersuchungen Ivesta 3.

Wie man das geeignete Mikroskop für die Sichtprüfung auswählt

Dieser Artikel hilft Anwendern bei der Auswahl eines Mikroskops als Hilfsmittel für die routinemäßige Sichtprüfung. Es werden wichtige Faktoren beschrieben, die berücksichtigt werden sollten.

How to Use a Digital Microscope to Streamline Inspection Processes

Watch this webinar for inspiration and expert advice on how to make quality control simpler, quicker, and easier. Learn how to perform comprehensive visual inspection, including comparison,…
Dynamic Signal Enhancement powered by Aivia:  Truly simultaneous multicolor imaging of live cells (U2OS) in 3D

Artificial Intelligence and Confocal Microscopy – What You Need to Know

This list of frequently asked questions provides “hands-on” answers and is a supplement to the introductory article about Dynamic Signal Enhancement powered by Aivia "How Artificial Intelligence…
Dynamic Signal Enhancement powered by Aivia: Truly simultaneous multicolor imaging of live cells (U2OS) in 3D

How Artificial Intelligence Enhances Confocal Imaging

In this article, we show how artificial intelligence (AI) can enhance your imaging experiments. Namely, how Dynamic Signal Enhancement powered by Aivia improves image quality while capturing the…

Designing your Research Study with Multiplexed IF Imaging

Multiplexed tissue analysis is a powerful technique that allows comparisons of cell-type locations and cell-type interactions within a single fixed tissue sample. It is common for researchers to ask…
REM-Aufnahme der vollständigen Li-NMC-Elektrodenprobe, die die beiden porösen Schichten und den Metallfilm in der Mitte der Struktur zeigt.

Querschnitt-Ionenstrahlfräsen von Batteriekomponenten

Für ein umfassendes Verständnis von Lithiumbatteriesystemen ist eine qualitativ hochwertige Oberflächenpräparation erforderlich, um die innere Struktur und Morphologie zu untersuchen. Aufgrund der…

How to Successfully Perform Live-Cell CLEM

The Leica Nano workflow provides a streamlined live-cell CLEM solution for getting insight bout structural changes of cellular components over time. Besides the technical handling described in the…

Proveo 8 with intraoperative OCT – a User Evaluation in an University Setting

Optical coherence tomography (OCT) makes structures in the eye visible that lie beneath the surface. When OCT is used intraoperatively, surgeons gain insight into possible pathological changes in the…
Sep 29, 2021
Fallstudie
Chirurgische Mikroskopie
Proveo 8 with intraoperative OCT – a User Evaluation in an University Setting

Be Confident in your Results with Cell DIVE Validated Antibodies

The Cell DIVE System includes a carefully curated list of hundreds of commercially available antibodies validated to offer optimal specificity and sensitivity in multiplexed imaging. That validation…

Optimal Visualization in Brain Surgery

This case study “Treatment of the Galassi type III arachnoid cyst with the M530 OHX surgical microscope from Leica Microsystems” documents the procedure step by step and shows the visualization…

Benefits of Combining STED and Lifetime

In this interview, Professor Alberto Diaspro talks about the advantages of the White Light Laser and the TauSTED capabilities of STELLARIS 8 STED. He speaks about his experience with the confocal…

Spectroscopic Evaluation of Red Blood Cells

Hemoglobinopathies are a major healthcare problem. This study presents a possible diagnostic tool for thalassemia which is based on confocal spectroscopy. This approach exploits spectral detection and…

How to use a Surgical Microscope as an Operating Room Nurse

Surgical microscopes play an essential role in the modern microsurgery procedures. It provides the surgeon, assistant and operating room staff with a magnified and illuminated high-quality image of…
HeLa Kyoto cells (HKF1, H2B-mCherry, alpha Tubulin, mEGFP). Left image: Maximum projection of a z-stack prior to ICC and LVCC. Right image: Maximum projection of a mosaic z-stack after ICC and LVCC.

How to Improve Live Cell Imaging with Coral Life

For live-cell CLEM applications, light microscopy imaging is a critical step for identifying the right cell in the right state at the right time. In this article, Leica experts share their insights on…

The Cryo-CLEM Journey

This article describes the Cryo-CLEM technology and the benefits it can provide for scientists. Additionally, some scientific publications are highlighted. Recent developments in cryo electron…

Clinical Symposium on OCT-guided Cornea Surgery

In this recording Prof. Mehta from Singapore National Eye Centre and Prof. Fontana from Santa Maria Nuova Hospital in Regio Emilia, Italy, share their expertise on corneal surgery. They present PK,…
The EM ICE Nano loading area

How to Keep Your Samples Under Physiological Conditions

The Coral Life workflow combines dynamic data with the best possible sample fixation by high pressure freezing. However, good sample preservation won’t help if your cells are stressed by temperature…

Fluorescence Lifetime-based Imaging Gallery

Confocal microscopy relies on the effective excitation of fluorescence probes and the efficient collection of photons emitted from the fluorescence process. One aspect of fluorescence is the emission…
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