Spatial Biology Reagents
Spatial biology researchers face increasing pressure to extract deeper biological insight from limited tissue. Traditional multiplex immunofluorescence workflows can be time-consuming and difficult to reproduce, often requiring trade-offs between plex level, signal quality, and experimental confidence.
ATTOAuriga, a modular spatial biology reagent ecosystem
Introducing ATTOAuriga, a modular spatial biology reagent ecosystem that enables researchers to build and adapt multiplex experiments using a defined set of interoperable reagents, from pre-validated antibody panels to conjugation kits for custom antibody barcoding, supporting confident cyclic imaging workflows.
Curious how ATTOAuriga can fit into your workflow? Contact us to discuss panels, conjugation options, and cyclic imaging strategies.
Key Benefits
Bright, clean signals
- Uses ATTOIrida fluorescent labels that hybridize specifically to Unique Antibody Identifiers (UAI) on antibodies
- Enzyme (DNase I) based signal removal clears fluorescence between cycles, minimizing signal carryover
- Designed from the ground-up for advanced high-plex immunofluorescence imaging
Built-in flexibility
- Pre-validated ATTOApollo panels for ready-to-use workflows
- ATTOConexa kits enable users to barcode their own antibodies
- Antibody barcoding allows flexible mapping of fluorescent labels through ATTOAdapt adapters
- Supports integration of user-generated antibodies alongside validated panels
Designed for reproducibility
- Defined reagent ecosystem with standardized components
- Validated for human FFPE tissue sections
- Consistent blocking, hybridization, and cycling chemistry across experiment
- May be suitable for fluorescence microscopes capable of detecting standard ATTOIrida channels
A modular approach to multiplex imaging
Building multiplex antibody panels can be time-consuming and costly, which can slow progress and increase experimental risk for spatial biology researchers.
ATTOAuriga, a modular reagent family
ATTOAuriga is a modular reagent family that supports repeated rounds of antibody labeling, imaging, and enzymatic signal removal. Each component plays a defined role in delivering reliable cyclic imaging performance while maintaining tissue integrity and signal quality.
- ATTOIrida fluorescent labels that hybridize specifically to Unique Antibody Identifiers (UAI) on antibodies
- Pre-validated ATTOApollo panels for ready-to-use workflows
- Defined reagent ecosystem with standardized components
Each component has a distinct role
ATTOApollo Panels
Pre-validated, ready-to-use antibody panels with Unique
Antibody Identifiers (UAI) barcodes.
ATTOConexa Kits
Conjugation kits for generating oligonucleotide barcoded
antibodies.
ATTOIrida Fluorescent Labels
Hybridization-based labels designed for cyclic imaging
workflows.
ATTOSilenta Blocking Buffer
Required buffer optimized for signal quality and reproducibility.
Note: This material was created and approved prior to the product launch, but only as a pre-announcement.
