Spatial Biology Reagents AttoAuriga

Spatial Biology Reagents

Spatial biology researchers face increasing pressure to extract deeper biological insight from limited tissue. Traditional multiplex immunofluorescence workflows can be time-consuming and difficult to reproduce, often requiring trade-offs between plex level, signal quality, and experimental confidence.

ATTOAuriga, a modular spatial biology reagent ecosystem

Introducing ATTOAuriga, a modular spatial biology reagent ecosystem that enables researchers to build and adapt multiplex experiments using a defined set of interoperable reagents, from pre-validated antibody panels to conjugation kits for custom antibody barcoding, supporting confident cyclic imaging workflows.

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Contact a local imaging specialist for expert advice on the right solution for your needs and budget.

Colon Mic Adenocarc DAPI

Key Benefits

Bright, clean signals

  • Uses ATTOIrida fluorescent labels that hybridize specifically to Unique Antibody Identifiers (UAI) on antibodies
  • Enzyme (DNase I) based signal removal clears fluorescence between cycles, minimizing signal carryover
  • Designed from the ground-up for advanced high-plex immunofluorescence imaging

Built-in flexibility

  • Pre-validated ATTOApollo panels for ready-to-use workflows
  • ATTOConexa kits enable users to barcode their own antibodies
  • Antibody barcoding allows flexible mapping of fluorescent labels through ATTOAdapt adapters
  • Supports integration of user-generated antibodies alongside validated panels

Designed for reproducibility

  • Defined reagent ecosystem with standardized components
  • Validated for human FFPE tissue sections
  • Consistent blocking, hybridization, and cycling chemistry across experiment
  • Suitable for fluorescence microscopes with detection spectra compatible with ATTOIrida labels

A modular approach to multiplex imaging

Building multiplex antibody panels can be time-consuming and costly, which can slow progress and increase experimental risk for spatial biology researchers. 

ATTOAuriga, a modular reagent family

ATTOAuriga is a modular reagent family that supports repeated rounds of antibody labeling, imaging, and enzymatic signal removal. Each component plays a defined role in delivering reliable cyclic imaging performance while maintaining tissue integrity and signal quality.

  • ATTOIrida fluorescent labels that hybridize specifically to Unique Antibody Identifiers (UAI) on antibodies
  • Pre-validated ATTOApollo panels for ready-to-use workflows
  • Defined reagent ecosystem with standardized components

Curious how ATTOAuriga can fit into your workflow? 

Contact us to discuss panels, conjugation options, and cyclic imaging strategies.

Each component has a distinct role

ATTOApollo Panels

Pre-validated, ready-to-use antibody panels with Unique
Antibody Identifiers (UAI) barcodes.

ATTOConexa Kits

Conjugation kits for generating oligonucleotide barcoded
antibodies.

ATTOIrida Fluorescent Labels

Hybridization-based labels designed for cyclic imaging
workflows.

ATTOSilenta Blocking Buffer

Required buffer optimized for signal quality and reproducibility.

Note: This material was created and approved prior to the product launch, but only as a pre-announcement.

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