ATTO 678H Carboxy Hydrophilic Fluorescent Label 5 mg

Like ATTO 643 and ATTO 647N, ATTO 678H belongs to a new generation of long-wavelength fluorescent markers. The dye's characteristic properties include strong absorption, good fluorescence quantum yield, and high thermal and photochemical stability.

Optical properties

• λ _abs = 678 nm
• ε _max = 1.5×10⁵ M ^-1 cm ^-1
• λ _fl = 708 nm
• n _fl = 20 %
• τ _fl = 1.5 ns
• CF ₂₆₀ = ε ₂₆₀ /ε _max = 0.12
• CF ₂₈₀ = ε ₂₈₀ / ε _max = 0.08

Like ATTO 643 and ATTO 647N, ATTO 678H belongs to a new generation of long-wavelength fluorescent markers. The dye's characteristic properties include strong absorption, good fluorescence quantum yield, and high thermal and photochemical stability. ATTO 678H is highly hydrophilic and highly water-soluble, and compared to ATTO 680, it exhibits significantly reduced aggregation behavior and a low tendency toward nonspecific binding. After coupling to a substrate, the dye is singly negatively charged. Unlike ATTO 680, it is not an electron acceptor; its fluorescence is not quenched by guanine, tryptophan, etc. Efficient fluorescence excitation occurs in the 665–695 nm range.

ATTO-TEC is a wholly owned subsidiary of Leica Microsystems