Claudia Mayrhofer , Ing.

Claudia Mayrhofer

Ing. Claudia Mayrhofer (born March 21, 1969) has been working since 2003 at the Center for Electron Microscopy in Graz. Renowned for her outstanding expertise in ultramicrotomy, she has extensive experience in both chemical and physical sample preparation. Her structured and goal-oriented approach to problem analysis, combined with intelligent optimization of measurements, instruments, and workflows in microtomy and cryo-ultramicrotomy, has made her a highly respected professional in her field. Her areas of activity include TEM and cryo-TEM, light microscopy, physical and chemical sample preparation, GC–MSD and GC–FID analyses, aroma compound analysis, and sensory evaluation. Her most recent publication is: Coffee – a ubiquitous substitute for uranyl acetate in staining of biological ultrathin sections for electron microscopy studies, Methods (2025), DOI: 10.1016/j.ymeth.2025.08.009.

SEM image of the sample consisting of reed and brewers’ spent grain after surface polishing using the UC Enuity cryochamber at -120°C. The sample was transferred to the cryo-SEM (Zeiss Sigma 300) using the EM VCT500 transfer system. Courtesy of Claudia Mayrhofer, ZFE, Graz, Austria.

Ultramicrotome UC Enuity in Practice: Stable 15 nm Sections at ZFE

After using the UCT and UC6 ultramicrotomes, Claudia Mayrhofer calls UC Enuity a leap in stability—so robust that vibrations and temperature shifts don’t spoil sections, even with multiple users. Auto…
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