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Vasundhara Agrawal , PhD

Vasundhara Agrawal

Vasundhara Agrawal is an Applications Manager for Spatial Biology Image Analysis at Leica Microsystems. She received her Ph.D. in Biomedical Engineering with specialization in Imaging and Biophotonics from Northwestern University. Her research expertise encompasses high-resolution molecular imaging, functional genomics, and physics-based statistical analysis to elucidate the intricacies of 3D genome architecture for applications in regenerative engineering. At Leica Microsystems, she works at the intersection of multiplexed whole-tissue imaging, AI-driven image analysis and spatial statistics to uncover molecular signatures and mechanisms underlying diverse biological models, including the tumor microenvironment in cancers originating from various sources, and neurodegenerative diseases such as Alzheimer's.

AI-Powered Multiplexed Image Analysis to Explore Colon Adenocarcinoma

In this application note, we demonstrate a spatial biology workflow via an AI-powered multiplexed image analysis-based exploration of the tumor immune microenvironment in colon adenocarcinoma.

A Meta-cancer Analysis of the Tumor Spatial Microenvironment

Learn how clustering analysis of Cell DIVE datasets in Aivia can be used to understand tissue-specific and pan-cancer mechanisms of cancer progression
Multiplexed Cell DIVE imaging of Colon Adenocarcinoma (CAC) tissue. A panel of approximately 30 biomarkers targeted towards various leukocyte lineages, epithelial, stromal, and endothelial cell types was utilized to characterize the tumor immune microenvironment in human colon adenocarcinoma (CAC) tissue.

Mapping the Landscape of Colorectal Adenocarcinoma with Imaging and AI

Discover deep insights in colon adenocarcinoma and other immuno-oncology realms through the potent combination of multiplexed imaging of Cell DIVE and Aivia AI-based image analysis
Clustering based analysis reveals various immune cell populations enriched in tumor cells within CT26.WT syngeneic mouse tumor models.

Spatial Architecture of Tumor and Immune Cells in Tumor Tissues

Dig deep into the spatial biology of cancer progression and mouse immune-oncology in this poster, and learn how tumor metabolism can effect immune cell function.
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