Contact & Support
Header Image

Learn & Share: EM Sample Preparation

To achieve the best results during examination in the Electron Microscope (EM), the perfect EM Sample Preparation (for TEM, SEM, AFM) is a prerequisite. The required techniques depend on the samples (biological samples, material samples) as well as on the application. EM Sample Preparation includes all methods of preparations from embedding, tissue processing, coating, immunogold labeling through ultrathin sectioning with ultramicrotomes, cryo-ultramicrotomy, cryosectioning, critical point drying, plunge freezing, freeze substitution, freeze fracturing, freeze drying, contrasting, cryofixation, high pressure freezing, cryo transfer, freeze etching, freeze fracture to ion beam milling, ion beam etching, and target preparation – mechanical grinding and polishing. Only if each step of sample preparation is of the highest quality, can optimum results be obtained from a high resolution electron microscope.

Related Topics

Useful Links

Communities and Web Sources network for scientists

bitesizebio.comOnline magazine and community for molecular and cell biology researchers

www.somersault1824.comResource for high-end scientific illustrations, images and animations

Search Engines and Data Bases

www.cellimagelibrary.orgPublic resource database of images, videos, and animations of cells meta search engine for genes and proteins

www.gopubmed.comSearch interface for pubmed of academic databases and search engines of Google's search engine for scientific article abstracts

Journals of open access journals

www.lifescied.orgCBE-Life Sciences Education – an ASCB online journal publication of exceptional research articles of Cell Science Journal of Experimental Biology Disease Models & Mechanisms Journal of Life Science Methods of Journals and Proceedings in Optics and Photonics - peer-reviewed journals on applied research in optics and photonics of Biophotonics, peer-reviewed, open-access, online publication B - the Royal Society's biological research journal Journal for microscopists and features on biomedical microscopy

Organizations / Institutes Society of America Microscopy Society Microscopical Society on microscopy for materials science; University of Cambridge, Department of Materials Science and Metallurgy American Society of Cell Biology company of biologists

Your bookmarks are missing?
Please send us your useful links!