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Differential Interference Contrast (DIC) Microscopy
This article demonstrates how differential interference contrast (DIC) can be actually better than brightfield illumination when using microscopy to image unstained biological specimens.
Phase Contrast and Microscopy
This article explains phase contrast, an optical microscopy technique, which reveals fine details of unstained, transparent specimens that are difficult to see with common brightfield illumination.
H&E Staining in Microscopy
If we consider the role of microscopy in pathologists’ daily routines, we often think of the diagnosis. While microscopes indeed play a crucial role at this stage of the pathology lab workflow, they…
How to Benefit from Digital Cytopathology
If you have thought of digital cytopathology as characterized by the digitization of glass slides, this webinar with Dr. Alessandro Caputo from the University Hospital of Salerno, Italy will broaden…
Factors for Selecting Clinical Microscopes
If you are considering the purchase of new clinical microscopes for yourself or your team, you will think about many options, vendors, and microscope models. Here are some tips to help you come to the…
The Time to Diagnosis is Crucial in Clinical Pathology
Abnormalities in tissues and fluids - that’s what pathologists are looking for when they examine specimens under the microscope. What they see and deduce from their findings is highly influential, as…
Perform Microscopy Analysis for Pathology Ergonomically and Efficiently
The main performance features of a microscope which are critical for rapid, ergonomic, and precise microscopic analysis of pathology specimens are described in this article. Microscopic analysis of…
Koehler Illumination: A Brief History and a Practical Set Up in Five Easy Steps
The technique of Koehler Illumination is one of the most important and fundamental techniques in achieving optimum imaging in any given light microscope set-up. Although it should be routinely used as…
Fields of Application
Fluorescence
Find out how fluorescence microscopes from Leica Microsystems support your research. Fluorescence is one of the most commonly used physical phenomena in biological and analytical microscopy for its…
Clinical Pathology
Learn how ergonomic microscopes from Leica Microsystems support accurate and timely diagnosis in clinical pathology.
Microscopy in Pathology
Analysis of specimens for pathology sometimes requires long hours working with a microscope. The result for the user may be physical discomfort and strain that can lead to reduced efficiency and the…
Anatomic Pathology
Learn how ergonomic microscopes from Leica Microsystems support efficient and accurate diagnosis in anatomic pathology.
DIC Microscopes
A DIC microscope is a widefield microscopy which has a polarization filter and Wollaston prism between the light source and condenser lens and also between the objective lens and camera sensor or…
Phase Contrast Light Microscopes
A phase contrast light microscope offers a way to view the structures of many types of biological specimens in greater contrast without the need of stains.
Darkfield Microscopes
The darkfield contrast method exploits diffraction or scattering of light from structures of a biological specimen or non-uniform features of a material sample.
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