David R. Barbero , PhD
Dr. David R. Barbero is an engineer and physicist who has over 15 years of experience in nanoscale opto-electronic materials, devices and displays. His work has been published in several top journals in Materials Science and Physics and highlighted in over 300 scientific newspapers and internet websites. He has a long experience in nano-patterning and nano-structuring of polymers and composites (optical lithography, nano-imprinting, colloidal, nanotubes, and polymer self-assembly). David obtained his PhD in Physics at the Cavendish Laboratory, University of Cambridge, UK, where he was a Marie-Curie Fellow, a European Cambridge Trust Scholar, and he was awarded the Abdus Salam runner-up prize in Physics from Cambridge University in 2009.
Molecular Mechanisms of Vascular Disease
This article discusses how the lamina, vascular cells, and nuclei of mouse aorta are more clearly resolved with a THUNDER Imager Tissue using Computational Clearing (CC) compared to conventional…Read article
Autophagy and Age-Related Pathologies
High-contrast imaging of the model organism C. elegans, a nematode, with the THUNDER Imager Model Organism using Small Volume Computational Clearing (SVCC) helps to better understand how autophagy and…Read article
Top Challenges for Visual Inspection
This article discusses the challenges encountered when performing visual inspection and rework using a microscope. Using the right type of microscope and optical setup is paramount in order to…Read article
How to select the right solution for visual inspection
This article helps users with the decision-making process when selecting a microscope as a solution for routine visual inspection. Important factors that should be considered are described.Read article
Localizing Bone Stem Cells In Vivo
This article demonstrates how undecalcified mouse bone samples can be investigated in detail more easily and rapidly with a cryohistological method used in combination with a THUNDER Imager Tissue and…Read article
Role of Mucins and Glycosylation in Dry Eye Disease
This article shows how fast, high-contrast, and sharp imaging of stratified human corneal epithelial cells with THUNDER imaging technology for dry eye disease (DED) research allows membrane ridges to…Read article
Skeletal Muscle Adaptation and Fibrotic Diseases
The mechanisms of how skeletal muscle adapts to fibrotic pathologies can be investigated more efficiently with fast, high-contrast imaging of C2C12 mouse myoblast cells which is described in this…Read article
Introduction to 21 CFR Part 11 and Related Regulations
This article provides an overview of regulations and guidelines for electronic records (data entry, storage, signatures, and approvals) used in the USA (21 CFR Part 11), EU (GMP Annex 11), and China…Read article
Monitoring Immunosuppressive Mechanisms from Infection
This application note discusses the importance of fast, sensitive, and haze-free imaging for the monitoring of immunosuppression in mouse lung epithelial tissue infected with the Puerto Rico 8…Read article
“Brains-In-A-Dish” from Induced Pluripotent Stem Cells (iPSCs)
This article discusses the benefits of using the THUNDER technology for imaging inside 3D human cortical brain organoids. These organoids are derived from human induced pluripotent stem cells (iPSCs)…Read article
Why is Manual Visual Inspection of Medical Devices so Challenging?
This article discusses how manual visual inspection, which is prevalent in the medical device industry, can lead to inconsistent results. It also addresses the challenges quality managers and…Read article
Keeping Particulate Contamination Under Control in Pharmaceutical Products
This article describes how a 2-methods-in-1 solution combining optical microscopy and laser induced breakdown spectroscopy (LIBS) can be utilized for identification of particulate contaminants in the…Read article
How does an Automated Rating Solution for Steel Inclusions Work?
The rating of non-metallic inclusions (NMIs) to determine steel quality is critical for many industrial applications. For an efficient and cost-effective steel quality evaluation, an automated NMI…Read article
Challenges Faced When Manually Rating Non-Metallic Inclusions (NMIs) to Determine Steel Quality
Rapid, accurate, and reliable rating of non-metallic inclusions (NMIs) is instrumental for the determination of steel quality. This article describes the challenges that arise from manual NMI rating,…Read article
Reasons Why There is Growing Need for Fast and Reliable Steel Quality Rating Solutions
Steel quality is critical for the manufacturing of high-quality components and products. Fast, reliable, and accurate detection and classification of inclusions has become essential for both component…Read article
Top Issues Related to Standards for Rating Non-Metallic Inclusions in Steel
Supplying components and products made of steel to users worldwide can require that a single batch be compliant with multiple steel quality standards. This user demand creates significant challenges…Read article
Key Factors for Efficient Cleanliness Analysis
In the automobile industry, even the smallest particles on single components can cause malfunctioning. Fuel, lubricant and urea filter systems are particularly vulnerable. Component cleanliness has…Read article
Brief Introduction to Surface Metrology
This report briefly discusses several important metrology techniques and standard definitions commonly used to assess the topography of surfaces, also known as surface texture or surface finish. With…Read article