Oliver Schlicker , Dr.

Oliver Schlicker

Oliver is a Senior Application Manager at Leica Microsystems. He received his PhD in Neuro-Cell-Biology from the University of Heidelberg, Germany. After heading the Imaging Facility at the IZI in Stuttgart, Germany he joined Leica Microsystems Wetzlar in 2008 as Application Manager, responsible for Advanced Fluorescence Widefield Microscopy.

Living HeLa cells stained with WGA-488 (yellow), SPY-Actin (cyan), and SiR-Tubulin (magenta). Instant Computational Clearing (ICC) was applied.

How to Perform Dynamic Multicolor Time-Lapse Imaging

Live-cell imaging sheds light on diverse cellular events. As many of these events have fast dynamics, the microscope imaging system must be fast enough to record every detail. One major advantage of…
3D Reconstruction of brain slide image_Mica

3D Tissue Imaging: From Fast Overview To High Resolution With One Click

3D Tissue imaging is a widespread discipline in the life sciences. Researchers use it to reveal detailed information of tissue composition and integrity, to make conclusions from experimental…
MDCK cysts on day 9

How To Perform Fast & Stable Multicolor Live-Cell Imaging

With the help of live-cell imaging researchers gain insights into dynamic processes of living cells up to whole organisms. This includes intracellular as well as intercellular activities. Protein or…
Developing zebrafish (Danio rerio) embryo, from sphere stage to somite stages.

Studying Early Phase Development of Zebrafish Embryos

VIDEO ON DEMAND - This second edition of MicaCam focuses on combining widefield and confocal imaging to study the early-stage development of zebrafish embryos (Danio rerio), from oocyte to…
U2OS cells stained with Hoechst for nuclei (blue), MitoTracker green (Mitochondria structure, green) and TMRE (active mitochondria, magenta) and SiR for tubulin (red). Simultaneous acquisition of four channel large area overview using Spiral scan feature using the 10x/1.20 CS2 Water MotCORR objective.

How To Get Multi Label Experiment Data With Full Spatiotemporal Correlation

VIDEO ON DEMAND - The first edition of MicaCam focuses on the special challenges of live cell experiments. Our hosts Lynne Turnbull and Oliver Schlicker use the example of studying the mitochondrial…

The Power of Pairing Adaptive Deconvolution with Computational Clearing

Deconvolution is a computational method used to restore the image of the object that is corrupted by the point spread function (PSF) along with sources of noise. In this technical brief, learn how the…

An Introduction to Computational Clearing

Many software packages include background subtraction algorithms to enhance the contrast of features in the image by reducing background noise. The most common methods used to remove background noise…

What is Photomanipulation?

The term photomanipulation describes a wide range of techniques that enable the microscopist the transition from passive observer to instigator of events by offering a way of interacting with their…
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