Kontaktieren Sie uns

Cell DIVE Multiplex-Bildgebungslösung

Grundlegender Fortschritt der Gewebeforschung durch offenes Multiplexing

Lesen Sie unsere neuesten Artikel

Pancreatic Ductal Adenocarcinoma with 11 Aerobic Glycolysis/Warburg Effect biomarkers shown – BCAT, Glut1, HK2, HTR2B, LDHA, NaKATPase, PCAD, PCK26, PKM2, SMA1, and Vimentin.

IBEX, Cell DIVE, and RNA-Seq: A Multi-omics Approach to Follicular Lymphoma

In a recent study by Radtke et al., a multi-omics spatial biology approach helps shed light on early relapsing lymphoma patients

Accelerating Discovery for Multiplexed Imaging of Diverse Tissues

Explore IBEX: Open-source multiplexed imaging. Join the collaborative IBEX Imaging Community for optimized tissue processing, antibody selection, and human atlas construction.
2D slice of colon cancer tissue stained with 30 markers and imaged using the Cell DIVE system. Analysis performed using Aivia 13’s new multiplex cell detection recipe and automatic clustering tool. Each phenotype denoted in a different color.

Transforming Multiplexed 2D Data into Spatial Insights Guided by AI

Aivia 13 handles large 2D images and enables researchers to obtain deep insights into microenvironment surrounding their phenotypes with millions of detected objects and automatic clustering up to 30…
Hepatocellular Carcinoma with 13 biomarkers shown – Beta-Catenin, CD3D, CD4, CD8a, CD31, CD44, CD163, DAPI, PanCK, PCK26, PD1, SMA, and Vimentin.

Understanding Tumor Heterogeneity with Protein Marker Imaging

Explore tumor heterogeneity and immune cell dynamics. See how quantitative imaging analysis reveals spatial relationships and molecular insights crucial for advancing cancer research and therapeutics.
Adult human Alzheimer’s brain demonstrating a panel of 15 markers.

The Shape of the Brain: Spatial Biology of Alzheimer’s Disease

Uncover cell identity and brain structure in Alzheimer's disease with Cell DIVE multiplexed imaging, demonstrating how spatial biology can lead to advances in therapy development for…
[Translate to German:] Co-detection of 10 extracellular matrix proteins and 3 topographical tissue landmarks by multiplex immunostaining within a single high-grade fibrous hotspot from a human hepatocellular carcinoma

In-situ-Identifizierung von Krebsstammzellnischen im Leberzellkarzinom

Die Multiplex-Bildgebung spielt eine entscheidende Rolle bei der Krebsforschung, da sie es Wissenschaftlern ermöglicht, tief in die komplexe Mikroumgebung von Tumoren einzudringen und einzigartige…
Esophageal tissue with a squamous cell carcinoma labelled with the 4 biomarkers PanCk, DAPI, NaKATPase, and Vimentin.

Discover how Multiplexed Bioimaging can Advance Cancer Research

Explore multiplexing with up to 60 biomarkers, enabling advanced tumor imaging approaches to gather precise, spatially-resolved single-cell data that helps enhance cancer research and clinical…
Pancreatic Ductal Adenocarcinoma with 11 Apoptosis biomarkers shown – BAK, BAX, BCL2, BCLXL, Caspase9, CIAP1, NaKATPase, PCK26, SMAC, Vimentin, and XIAP.

Multiplexing with Luke Gammon: Advance your Spatial Biology Research

Learn how multiplexing imaging and spatial biology can help researchers better understand complex biological systems. In this interview, Dr. Gammon and Dr. Pointu of Leica Microsystems discuss pain…
[Translate to German:] Multi-tissue array with 4 markers shown including DAPI, NaKATPase, PanCk, and Vimentin.

Räumliche Biologie: Erwägung neuer Wege

Räumliche Biologie: Forschung zu Anordnung und Interaktion von Molekülen, Zellen und Geweben in ihrem nativen räumlichen Kontext
[Translate to German:] Cell counts for each biomarker were divided by total number of cells to give a percentage of biomarker positive cells out of total cells for each biomarker.

Methoden zur Verbesserung der Reproduzierbarkeit in der räumlichen Biologieforschung

Durch den Einsatz von Automatisierung, hochwertigen Antikörpern und einem bewährten Multiplex-Imaging-Workflow ist Cell DIVE in der Lage, reproduzierbare Ergebnisse zu liefern. In diesem Poster…
PDAC Multiplexed imaging of CST panels enables an examination of immune cell components in pancreatic ductal adenocarcinoma (IPDAC) tissue on a single slide.

Characterizing tumor environment to reveal insights and spatial resolution

Antibodies from Cell Signaling Technology are validated for use with the Cell DIVE multiplexing workflow and used to probe cell lineages in the tumor microenvironment
Pancreatic Ductal Adenocarcinoma with 5 biomarkers shown – SMA, PanCK PCK26, PanCK AE1, Vimentin, and Glut1.

Dig Deeper Into the Complexities of Pancreatic Cancer with Multiplex Imaging

Cell DIVE is an iterative staining workflow for multiplexed imaging that unveils biological pathways to dig deeper into the complexities of pancreatic cancer.
How is microscopy used in spatial biology - Teaserimage

How is Microscopy Used in Spatial Biology? A Microscopy Guide

Different spatial biology methods in microscopy, such as multiplex imaging, are helping to better understand tissue landscapes. Learn more in this microscopy guide.
Cell DIVE Multiplex Imaging Solution

Complex Made Simple: Antibodies in Multiplexed Imaging

Build panels, plan studies, and get the most from precious reagents using this antibody multiplexing guide from Leica Microsystems
Pancreatic ductal adenocarcinoma tissue section imaged with Cell DIVE

Multiplexed Imaging Types, Benefits and Applications

Multiplexed imaging is an emerging and exciting way to extract information from human tissue samples by visualizing many more biomarkers than traditional microscopy. By observing many biomarkers…
Pancreatic ductal adenocarcinoma tissue section imaged with Cell DIVE showing 30 biomarkers

Multiplexed Imaging Glossary

Human tissues contain a many different biomarkers which can be explored to reveal the workings of biological pathways and interrogate disease states. Recent technological advances have made it…
Normal skin imaged with Cell DIVE, 11 biomarkers shown.

Tumor MHC Expression and Intralesional IL2 Response in Melanoma

Genomics profiling and Cell DIVE multiplex imaging allows researchers to understand the immune cell phenotypes that most strongly predict response to IL2 immunotherapy in melanoma patients suffering…
Colon Adenocarcinoma. Four biomarkers shown: NaK, CD8, CD4 and Sma1. T-Cells shown in red and yellow.

Multiplex Imaging Reveals Survival Markers after Cancer Care

Colorectal cancer is a high incidence and high mortality cancer. Currently, postoperative chemotherapy benefits only a minority of patients, and thus, new tools are necessary to screen patients and…
Colon adenocarcinoma with 13 biomarkers shown

Hyperplex Cancer Tissue Analysis at Single Cell Level with Cell DIVE

The ability to study how lymphoma cell heterogeneity is influenced by the cells’ response to their microenvironment, especially at the mutational, transcriptomic, and protein levels. Protein…

Designing your Research Study with Multiplexed IF Imaging

Multiplexed tissue analysis is a powerful technique that allows comparisons of cell-type locations and cell-type interactions within a single fixed tissue sample. It is common for researchers to ask…

Be Confident in your Results with Cell DIVE Validated Antibodies

The Cell DIVE System includes a carefully curated list of hundreds of commercially available antibodies validated to offer optimal specificity and sensitivity in multiplexed imaging. That validation…

Overcoming Multiplexed Imaging Roadblocks

Whether a single slide or a batch of slides processed on multiple Cell DIVE imagers, every step carried out by the Cell DIVE Acquisition Software eliminates distortions and artifacts and seamlessly…

Anwendungsbereiche

Krebsforschung

Krebs ist eine komplexe und heterogene Krankheit, die durch Zellen verursacht wird, denen die Wachstumsregulation fehlt. Genetische und epigenetische Veränderungen in einer Zelle oder einer Gruppe von…
Background image
Scroll to top