ATTO 465 DOPE Labeled Phospholipid 1 mg
ATTO-Dye Labeled Phospholipids
In recent years the investigation of biological membranes, e.g. intracellular membranes of live cells, plasma membranes etc., has become a major subject of interest. As a result there is a growing demand for fluorescent dye-labeled lipids, in particular glycero-phospholipids, to be incorporated in biological membranes. ATTO-TEC offers a variety of glycero-phospholipids, carrying one or two fatty acid chains (lipophilic groups) and a phosphate ester residue (hydrophilic group).
ATTO-dye fluorescent phospholipids are labeled at the hydrophilic head group. After incorporation in, e.g., a plasma membrane (phospholipid bilayer) the fluorophore is located at the water/lipid interface of the membrane.
"ATTO-TEC is a wholly owned subsidiary of Leica Microsystems"
Currently we provide the phospholipids
- 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE),
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE),
- 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (PPE)
- 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine (DMPE), and
- 1,2-dilauroyl-sn-glycero-3-phosphoethanolamine (DLPE)
labeled with ATTO-dyes.
ATTO-TEC is a wholly owned subsidiary of Leica Microsystems
ATTO 465
ATTO 465 is a novel fluorescent label derived from the well-known dye Acriflavin. Characteristic features of the label are strong absorption, high fluorescence quantum yield, and high thermal and photo-stability. In aqueous solution the dye shows a surprisingly large Stokes-shift of 55 nm. The dye shows intense and long-lived phosphorescence in solid matrix, in particular at low temperatures. ATTO 465 is moderately hydrophilic. The fluorescence can be excited efficiently in the range 420 - 465 nm.
